(Q37803419)

23 August 2017

Roles for lysophospholipid S1P receptors in multiple sclerosis (English)

1 reference

23 August 2017

0 references

Kyoko Noguchi

1

1 reference

PubMed ID

20979571

23 August 2017

Jerold Chun

series ordinal

2

1 reference

23 August 2017

28 October 2010

1 reference

Critical Reviews in Biochemistry and Molecular Biology

23 August 2017

1 reference

23 August 2017

46

1 reference

23 August 2017

1

1 reference

23 August 2017

2-10

1 reference

Astrocyte-endothelial interactions at the blood-brain barrier

23 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

S1P1 receptor directs the release of immature B cells from bone marrow into blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Autocrine and paracrine roles of sphingosine-1-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Extracellular release of newly synthesized sphingosine-1-phosphate by cerebellar granule cells and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720 alters lymphocyte homing and protects allografts without inducing general immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720 (fingolimod) in renal transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Follicular shuttling of marginal zone B cells facilitates antigen transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

The blood-brain-barrier in multiple sclerosis: functional roles and therapeutic targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine-1-phosphate mediates migration of mature dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Pulmonary endothelial cell barrier enhancement by FTY720 does not require the S1P1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720 rescue therapy in the dark agouti rat model of experimental autoimmune encephalomyelitis: expression of central nervous system genes and reversal of blood-brain-barrier damage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Multiple sclerosis--the plaque and its pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Amelioration of experimental autoimmune encephalomyelitis in Lewis rats by FTY720 treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

B-cell depletion with rituximab in relapsing-remitting multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Lysophospholipid receptors: signaling and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Microglia and multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine 1-phosphate regulates peritoneal B-cell trafficking for subsequent intestinal IgA production.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

The sphingosine-1-phosphate receptor agonist FTY720 modulates dendritic cell trafficking in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720 reduces inflammation and promotes functional recovery after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Multiple sclerosis: closing in on an oral treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

B cells and autoantibodies in the pathogenesis of multiple sclerosis and related inflammatory demyelinating diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Physiologically based pharmacokinetic modeling of FTY720 (2-amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in rats after oral and intravenous doses.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

21 January 2018

Dissecting demyelination

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Cyclical and dose-dependent responses of adult human mature oligodendrocytes to fingolimod.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Essential role for sphingosine kinases in neural and vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Role of natural killer cells in the pathogenesis and progression of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Astrocytes in multiple sclerosis: a product of their environment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Phosphorylated FTY720 stimulates ERK phosphorylation in astrocytes via S1P receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720 ameliorates MOG-induced experimental autoimmune encephalomyelitis by suppressing both cellular and humoral immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Antiproliferative properties of sphingosine-1-phosphate in human hepatic myofibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Growth factor pre-treatment differentially regulates phosphoinositide turnover downstream of lysophospholipid receptor and metabotropic glutamate receptors in cultured rat cerebrocortical astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Finding a way out: lymphocyte egress from lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Accumulation of fingolimod (FTY720) in lymphoid tissues contributes to prolonged efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

A role for S1P signalling in axon guidance in the Xenopus visual system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720, a novel immunomodulator: efficacy and safety results from the first phase 2A study in de novo renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Edg-8 receptors are preferentially expressed in oligodendrocyte lineage cells of the rat CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Microglial activation state and lysophospholipid acid receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Astrocytes--friends or foes in multiple sclerosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine-1-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine 1-phosphate induces the production of glial cell line-derived neurotrophic factor and cellular proliferation in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Characterization of lysophosphatidic acid and sphingosine-1-phosphate-mediated signal transduction in rat cortical oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

FTY720 attenuates accumulation of EMAP-II+ and MHC-II+ monocytes in early lesions of rat traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2010.522975

10.3109/10409238.2010.522975

21 January 2018

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

20979571