(Q37805595)

English

Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

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scholarly article

1 reference

Europe PubMed Central

23 August 2017

Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies (English)

1 reference

Europe PubMed Central

23 August 2017

Anette Müllertz

3

0 references

author name string

Karen Kleberg

1

1 reference

Europe PubMed Central

23 August 2017

Jette Jacobsen

2

1 reference

Europe PubMed Central

23 August 2017

publication date

1 November 2010

1 reference

Europe PubMed Central

23 August 2017

Journal of Pharmacy and Pharmacology

1 reference

Europe PubMed Central

23 August 2017

62

1 reference

Europe PubMed Central

23 August 2017

1656-1668

1 reference

Europe PubMed Central

23 August 2017

11

1 reference

Europe PubMed Central

23 August 2017

The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension

1 reference

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Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

1 reference

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21 January 2018

Intestinal absorption of penclomedine from lipid vehicles in the conscious rat: contribution of emulsification versus digestibility

1 reference

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21 January 2018

Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: a case study with amprenavir

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21 January 2018

Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings

1 reference

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21 January 2018

Canine intestinal contents vs. simulated media for the assessment of solubility of two weak bases in the human small intestinal contents.

1 reference

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21 January 2018

Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum.

1 reference

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A clinical single-pass perfusion investigation of the dynamic in vivo secretory response to a dietary meal in human proximal small intestine.

1 reference

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21 January 2018

Isolation and properties of the mixed lipid micelles present in intestinal content during fat digestion in man

1 reference

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21 January 2018

Analysis of conjugated and unconjugated bile acids in serum and jejunal fluid of normal subjects.

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The characteristics of mixed micellar solutions with particular reference to bile

1 reference

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Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products

1 reference

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Charged lipid vesicles: effects of salts on bending rigidity, stability, and size.

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On the propensity of phosphatidylglycerols to form interdigitated phases

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Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging

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Tablet disintegration and drug dissolution in viscous media: paracetamol IR tablets

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21 January 2018

Effect of elevated viscosity in the upper gastrointestinal tract on drug absorption in dogs.

1 reference

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Biliary secretion of phosphatidylcholine and its molecular species in cholecystectomized T-tube patients: effects of bile acid hydrophilicity.

1 reference

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Solubilisation of poorly water-soluble drugs during in vitro lipolysis of medium- and long-chain triacylglycerols

1 reference

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21 January 2018

Dissolution media simulating the intralumenal composition of the small intestine: physiological issues and practical aspects.

1 reference

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21 January 2018

Oxidative stability of egg and soy lecithin as affected by transition metal ions and pH in emulsion

1 reference

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21 January 2018

Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update.

1 reference

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21 January 2018

Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds.

1 reference

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21 January 2018

In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media

1 reference

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21 January 2018

Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity

1 reference

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Postprandial changes in solubilizing capacity of human intestinal fluids for BCS class II drugs.

1 reference

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Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol

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Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling

1 reference

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21 January 2018

Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides

1 reference

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21 January 2018

Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound

1 reference

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Application of biorelevant dissolution tests to the prediction of in vivo performance of diclofenac sodium from an oral modified-release pellet dosage form

1 reference

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Dynamic dissolution testing to establish in vitro/in vivo correlations for montelukast sodium, a poorly soluble drug

1 reference

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Biorelevant dissolution media as a predictive tool for glyburide a class II drug.

1 reference

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21 January 2018

In vitro systems for studying intestinal drug absorption

1 reference

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21 January 2018

Simulated intestinal fluid as transport medium in the Caco-2 cell culture model.

1 reference

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21 January 2018

Effect of food intake on the oral absorption of poorly water-soluble drugs: in vitro assessment of drug dissolution and permeation assay system

1 reference

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Optimisation of the caco-2 permeability assay using experimental design methodology

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Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanism

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A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt:fatty acid micellar systems using the CaCo-2 cell culture model.

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Use of simulated intestinal fluids with Caco-2 cells and rat ileum

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Enhanced transport of a novel anti-HIV agent--cosalane and its congeners across human intestinal epithelial (Caco-2) cell monolayers

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Effect of simulated intestinal fluid on drug permeability estimation across Caco-2 monolayers.

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Biorelevant refinement of the Caco-2 cell culture model to assess efficacy of paracellular permeability enhancers

1 reference

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IVIVC in oral absorption for fenofibrate immediate release tablets using a dissolution/permeation system

1 reference

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Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds

1 reference

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21 January 2018

In vitro versus canine data for predicting input profiles of isosorbide-5-mononitrate from oral extended release products on a confidence interval basis.

1 reference

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21 January 2018

A comparison of the solubility of danazol in human and simulated gastrointestinal fluids

1 reference

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A dynamic in vitro lipolysis model

1 reference

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21 January 2018

Identifiers

10.1111/J.2042-7158.2010.01023.X

1 reference

Europe PubMed Central

23 August 2017

1 reference

Europe PubMed Central

23 August 2017

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