(Q37809730)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

2 references

23 November 2020

1 May 2021

Radiolabeled small molecule protein kinase inhibitors for imaging with PET or SPECT (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

positron emission tomography

16 January 2020

main subject

1 reference

single-photon emission computed tomography

23 November 2020

1 reference

1 May 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Sylvain Houle

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Henry F VanBrocklin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Alan A Wilson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Neil Vasdev

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

15 November 2010

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

23 November 2020

1 May 2021

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

23 November 2020

1 May 2021

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

8260-8278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

16 January 2020

copyright license

2 references

23 November 2020

The multifunctional calcium/calmodulin-dependent protein kinase: from form to function

1 May 2021

0 references

1 reference

12 December 2020

Protein kinases--the major drug targets of the twenty-first century?

1 reference

12 December 2020

Synthesis and positron emission tomography studies of carbon-11-labeled imatinib (Gleevec).

1 reference

12 December 2020

Rhenium and technetium complexes bearing quinazoline derivatives: progress towards a 99mTc biomarker for EGFR-TK imaging

1 reference

12 December 2020

Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development

1 reference

12 December 2020

N-(4-Meth-oxy-phen-yl)-N'-(5-nitro-1,3-thia-zol-2-yl)urea

1 reference

12 December 2020

MicroPET detection of enhanced 18F-FDG utilization by PKA inhibitor in awake rat brain

1 reference

12 December 2020

Imaging of EGFR and EGFR tyrosine kinase overexpression in tumors by nuclear medicine modalities.

1 reference

12 December 2020

Synthesis, 11C labeling and biological properties of derivatives of the tyrphostin AG957.

1 reference

12 December 2020

Molecular imaging as a tool for personalized and targeted anticancer therapy

1 reference

12 December 2020

Development of a new epidermal growth factor receptor positron emission tomography imaging agent based on the 3-cyanoquinoline core: synthesis and biological evaluation

1 reference

12 December 2020

Carbon-11-forskolin: a ligand for visualization of the adenylate cyclase-related second messenger system

1 reference

12 December 2020

The tyrosine kinase inhibitor PD153035: implication of labeling position on radiometabolites formed in vitro

1 reference

12 December 2020

Oncogenic kinase signalling

1 reference

12 December 2020

A fully automated two-step synthesis of an (18)F-labelled tyrosine kinase inhibitor for EGFR kinase activity imaging in tumors

1 reference

12 December 2020

Synthesis of carbon-11 labeled fluorinated 2-arylbenzothiazoles as novel potential PET cancer imaging agents.

1 reference

12 December 2020

Dynamics of signaling by PKA.

1 reference

12 December 2020

Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas.

1 reference

12 December 2020

Molecular imaging to select cancer therapy and evaluate treatment response

1 reference

12 December 2020

Synthesis and preclinical evaluation of [(11)C]PAQ as a PET imaging tracer for VEGFR-2.

1 reference

12 December 2020

Molecular imaging of epidermal growth factor receptor expression-activity at the kinase level in tumors with positron emission tomography

1 reference

12 December 2020

Direct fixation of [(11)C]-CO(2) by amines: formation of [(11)C-carbonyl]-methylcarbamates.

1 reference

12 December 2020

Synthesis and biological evaluation of a fluorine-18 derivative of dasatinib.

1 reference

12 December 2020

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

12 December 2020

Potential (18)F-labeled biomarkers for epidermal growth factor receptor tyrosine kinase.

1 reference

12 December 2020

Synthesis and ex vivo evaluation of carbon-11 labelled N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea ([11C]AR-A014418): a radiolabelled glycogen synthase kinase-3beta specific inhibitor for PET studies.

1 reference

12 December 2020

Cancer molecular imaging: radionuclide-based biomarkers of the epidermal growth factor receptor (EGFR).

1 reference

12 December 2020

Novel carbon-11 labeled 4-dimethylamino-but-2-enoic acid [4-(phenylamino)-quinazoline-6-yl]-amides: potential PET bioprobes for molecular imaging of EGFR-positive tumors

1 reference

12 December 2020

Multimodality imaging of the HER-kinase axis in cancer

1 reference

12 December 2020

The first design and synthesis of [11C]MKC-1 ([11C]Ro 31-7453), a new potential PET cancer imaging agent

1 reference

12 December 2020

Radioiodination of new EGFR inhibitors as potential SPECT agents for molecular imaging of breast cancer

1 reference

12 December 2020

Novel iodine-124 labeled EGFR inhibitors as potential PET agents for molecular imaging in cancer

1 reference

12 December 2020

Radiotracer synthesis from [(11)C]-iodomethane: a remarkably simple captive solvent method.

1 reference

12 December 2020

Synthesis and application of isocyanates radiolabeled with carbon-11.

1 reference

12 December 2020

Synthesis and radiopharmacological investigation of 3-[4'-[(18)F]fluorobenzylidene]indolin-2-one as possible tyrosine kinase inhibitor

1 reference

12 December 2020

Radiosynthesis and radiopharmacological evaluation of cyclin-dependent kinase 4 (Cdk4) inhibitors

1 reference

12 December 2020

Strategies for molecular imaging of epidermal growth factor receptor tyrosine kinase in cancer

1 reference

12 December 2020

Rationally designed PKA inhibitors for positron emission tomography: Synthesis and cerebral biodistribution of N-(2-(4-bromocinnamylamino)ethyl)-N-[11C]methyl-isoquinoline-5-sulfonamide.

1 reference

12 December 2020

Experimental results and related clinical implications of PET detection of epidermal growth factor receptor (EGFr) in cancer

1 reference

12 December 2020

One-pot, direct incorporation of [11C]CO2 into carbamates

1 reference

12 December 2020

[18F]Fluorothymidine positron emission tomography before and 7 days after gefitinib treatment predicts response in patients with advanced adenocarcinoma of the lung

1 reference

12 December 2020

Mixed-lineage kinases: a target for the prevention of neurodegeneration

1 reference

12 December 2020

Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development.

1 reference

12 December 2020

The lessons of GIST--PET and PET/CT: a new paradigm for imaging

1 reference

12 December 2020

Evaluation of radiolabeled ML04, a putative irreversible inhibitor of epidermal growth factor receptor, as a bioprobe for PET imaging of EGFR-overexpressing tumors

1 reference

12 December 2020

Molecular imaging of EGFR kinase activity in tumors with 124I-labeled small molecular tracer and positron emission tomography.

1 reference

12 December 2020

Positron emission tomography (PET) imaging with [11C]-labeled erlotinib: a micro-PET study on mice with lung tumor xenografts.

1 reference

12 December 2020

AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test

1 reference

12 December 2020

Labeled 3-aryl-4-indolylmaleimide derivatives and their potential as angiogenic PET biomarkers

1 reference

12 December 2020

Radiosynthesis of ML03, a novel positron emission tomography biomarker for targeting epidermal growth factor receptor via the labeling synthon: [11C]acryloyl chloride

1 reference

12 December 2020

Synthesis and activity of C11-modified wortmannin probes for PI3 kinase

1 reference

12 December 2020

Radiosynthesis and initial in vitro evaluation of [18F]F-PEG6-IPQA--a novel PET radiotracer for imaging EGFR expression-activity in lung carcinomas.

1 reference

12 December 2020

PET-based biodistribution and radiation dosimetry of epidermal growth factor receptor-selective tracer 11C-PD153035 in humans

1 reference

12 December 2020

Iodination and radiolabeling of alpha-allocryptopine with iodine-125.

1 reference

12 December 2020

Evaluation of modified PEG-anilinoquinazoline derivatives as potential agents for EGFR imaging in cancer by small animal PET.

1 reference

12 December 2020

The effect of the [18F]-PEG group on tracer qualification of [4-(phenylamino)-quinazoline-6-YL]-amide moiety--an EGFR putative irreversible inhibitor

1 reference

12 December 2020

Molecular imaging in drug development

1 reference

12 December 2020

Synthesis of [18F]SU11248, a new potential PET tracer for imaging cancer tyrosine kinase

1 reference

12 December 2020

PET imaging with 18F-FLT and thymidine analogs: promise and pitfalls

1 reference

12 December 2020

Synthesis of [11C]Iressa as a new potential PET cancer imaging agent for epidermal growth factor receptor tyrosine kinase

1 reference

12 December 2020

In vivo positron emission tomography (PET) imaging of mesenchymal-epithelial transition (MET) receptor

1 reference

12 December 2020

(124)I-iodopyridopyrimidinone for PET of Abl kinase-expressing tumors in vivo.

1 reference

12 December 2020

Radiosynthesis of N-[(11)C]-methyl-hydroxyfasudil as a new potential PET radiotracer for rho-kinases (ROCKs).

1 reference

12 December 2020

The role of glycogen synthase kinase 3 in the early stages of Alzheimers' disease.

1 reference

12 December 2020

A molecular and cellular theory of depression

1 reference

12 December 2020

Vascular endothelial growth factor receptor as target for advanced non-small cell lung cancer therapy

1 reference

12 December 2020

In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants.

1 reference

12 December 2020

Radiolabelled receptor-tyrosine-kinase targeting drugs for patient stratification and monitoring of therapy response: prospects and pitfalls.

1 reference

12 December 2020

Growth factors and cancer

1 reference

12 December 2020

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

1 reference

12 December 2020

Molecular recognition of protein kinase binding pockets for design of potent and selective kinase inhibitors

1 reference

12 December 2020

Formation of fluorine-18 labeled diaryl ureas--labeled VEGFR-2/PDGFR dual inhibitors as molecular imaging agents for angiogenesis

1 reference

12 December 2020

Synthesis and in vitro examination of [124I]-, [125I]- and [131I]-2-(4-iodophenylamino) pyrido[2,3-d]pyrimidin-7-one radiolabeled Abl kinase inhibitors

1 reference

12 December 2020

10.3390/MOLECULES15118260

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079565%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference