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The search for new therapies for human cytomegalovirus infections.
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1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
title
The search for new therapies for human cytomegalovirus infections
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
main subject
Cytomegalovirus
0 references
author
Mark Prichard
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
author name string
Earl R Kern
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
publication date
21 November 2010
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
published in
Virus Research
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
volume
157
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
page(s)
212-221
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
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6 September 2017
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6 September 2017
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Inhibition of ganciclovir-susceptible and -resistant human cytomegalovirus clinical isolates by the benzimidazole L-riboside 1263W94
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6 September 2017
Susceptibilities of human cytomegalovirus clinical isolates to BAY38-4766, BAY43-9695, and ganciclovir
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6 September 2017
A novel nonnucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products
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6 September 2017
Rising pp65 antigenemia during preemptive anticytomegalovirus therapy after allogeneic hematopoietic stem cell transplantation: risk factors, correlation with DNA load, and outcomes
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6 September 2017
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6 September 2017
Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells
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6 September 2017
Prediction of cytomegalovirus load and resistance patterns after antiviral chemotherapy
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6 September 2017
In vitro activities of methylenecyclopropane analogues of nucleosides and their phosphoralaninate prodrugs against cytomegalovirus and other herpesvirus infections
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6 September 2017
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6 September 2017
Effective treatment of murine cytomegalovirus infections with methylenecyclopropane analogues of nucleosides
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6 September 2017
Synthesis and antiviral activity of phosphoralaninate derivatives of methylenecyclopropane analogues of nucleosides
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6 September 2017
Single-dose pharmacokinetics of valganciclovir in HIV- and CMV-seropositive subjects
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6 September 2017
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6 September 2017
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6 September 2017
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6 September 2017
Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56
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6 September 2017
Inhibition of human cytomegalovirus DNA maturation by a benzimidazole ribonucleoside is mediated through the UL89 gene product
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6 September 2017
Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus
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6 September 2017
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication
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6 September 2017
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6 September 2017
Value of animal models to evaluate agents with potential activity against human cytomegalovirus
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6 September 2017
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6 September 2017
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6 September 2017
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14 September 2017
Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action
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14 September 2017
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14 September 2017
Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments
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14 September 2017
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14 September 2017
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14 September 2017
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14 September 2017
Synthesis and antiviral evaluation of alkoxyalkyl esters of acyclic purine and pyrimidine nucleoside phosphonates against HIV-1 in vitro
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14 September 2017
Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses
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14 September 2017
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity
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14 September 2017
Mechanism of action of the ribopyranoside benzimidazole GW275175X against human cytomegalovirus
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14 September 2017
Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro
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14 September 2017
Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus
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14 September 2017
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14 September 2017
Foscarnet. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections
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14 September 2017
Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo
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14 September 2017
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28 September 2017
2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections
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28 September 2017
Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766): in vitro and in vivo antiviral activity and mechanism of action
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28 September 2017
In vitro and in vivo activity of 1-O-hexadecylpropanediol-3-phospho-ganciclovir and 1-O-hexadecylpropanediol-3-phospho-penciclovir in cytomegalovirus and herpes simplex virus infections.
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28 September 2017
Inhibitors of human cytomegalovirus replication drastically reduce the activity of the viral protein kinase pUL97.
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28 September 2017
Indolocarbazoles exhibit strong antiviral activity against human cytomegalovirus and are potent inhibitors of the pUL97 protein kinase
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28 September 2017
(Z)- and (E)-2-(hydroxymethylcyclopropylidene)-methylpurines and pyrimidines as antiviral agents
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28 September 2017
(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity
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28 September 2017
Identification of enzymes catalyzing two-step phosphorylation of cidofovir and the effect of cytomegalovirus infection on their activities in host cells
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28 September 2017
A novel selective broad-spectrum anti-DNA virus agent
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28 September 2017
Human cytomegalovirus glycoproteins
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28 September 2017
Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir.
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23 June 2018
Effect of oral treatment with (S)-HPMPA, HDP-(S)-HPMPA or ODE-(S)-HPMPA on replication of murine cytomegalovirus (MCMV) or human cytomegalovirus (HCMV) in animal models.
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23 June 2018
Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease
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23 June 2018
Human cytomegalovirus UL27 is not required for viral replication in human tissue implanted in SCID mice
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23 June 2018
Rational development of beta-peptide inhibitors of human cytomegalovirus entry
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23 June 2018
Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome
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23 June 2018
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23 June 2018
Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) against guinea pig cytomegalovirus infection in cultured cells and in guinea pigs
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23 June 2018
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23 June 2018
Incidence and clinical features of ganciclovir-resistant cytomegalovirus disease in heart transplant recipients
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1 September 2018
Fluoroanalogues of anti-cytomegalovirus agent cyclopropavir: synthesis and antiviral activity of (E)- and (Z)-9-{[2,2-bis(hydroxymethyl)-3-fluorocyclopropylidene]methyl}-adenines and guanines.
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1 September 2018
Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine.
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1 September 2018
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1 September 2018
Ether lipid ester derivatives of cidofovir inhibit polyomavirus BK replication in vitro.
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1 September 2018
Effect of maternal treatment with cyclic HPMPC in the guinea pig model of congenital cytomegalovirus infection
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1 September 2018
Ether lipid-ester prodrugs of acyclic nucleoside phosphonates: activity against adenovirus replication in vitro
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1 September 2018
(Z)- and (E)-[2-Fluoro-2-(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines, a new class of methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity
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1 September 2018
Outcome of low-dose ganciclovir for cytomegalovirus disease prophylaxis in renal-transplant recipients
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1 September 2018
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1 September 2018
Efficacy of ganciclovir and cidofovir against human cytomegalovirus replication in SCID mice implanted with human retinal tissue
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1 September 2018
Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides
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1 September 2018
Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial
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1 September 2018
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1 September 2018
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1 September 2018
Direct targeting of human cytomegalovirus protein kinase pUL97 by kinase inhibitors is a novel principle for antiviral therapy
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1 September 2018
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1 September 2018
High incidence of ganciclovir-resistant cytomegalovirus infection among lung transplant recipients receiving preemptive therapy
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1 September 2018
Rate of emergence of cytomegalovirus (CMV) mutations in leukocytes of patients with acquired immunodeficiency syndrome who are receiving valganciclovir as induction and maintenance therapy for CMV retinitis
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1 September 2018
Predictive efficacy of SCID-hu mouse models for treatment of human cytomegalovirus infections.
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1 September 2018
Emergence of ganciclovir-resistant cytomegalovirus disease among recipients of solid-organ transplants.
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1 September 2018
Enhanced oral absorption and antiviral activity of 1-O-octadecyl-sn-glycero-3-phospho-acyclovir and related compounds in hepatitis B virus infection, in vitro
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PubMed Central
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1 September 2018
Intravenous cidofovir for peripheral cytomegalovirus retinitis in patients with AIDS. A randomized, controlled trial
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PubMed Central
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1 September 2018
Pharmacokinetics, bioavailability, metabolism, and tissue distribution of cidofovir (HPMPC) and cyclic HPMPC in rats
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PubMed Central
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1 September 2018
Initiation of human cytomegalovirus infection requires initial interaction with cell surface heparan sulfate
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PubMed Central
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1 September 2018
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease
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1 October 2018
A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance
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7 January 2021
Cytomegalovirus UL97 kinase mutations that confer maribavir resistance
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7 January 2021
Effect of acyclovir treatment on acute and chronic murine cytomegalovirus infection
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Development of new cytomegalovirus UL97 and DNA polymerase mutations conferring drug resistance after valganciclovir therapy in allogeneic stem cell recipients
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7 January 2021
Erratum: A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells
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7 January 2021
Treatment of cytomegalovirus retinitis with trisodium phosphonoformate hexahydrate (Foscarnet)
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Synthesis of 2,2,3-tris(hydroxymethyl)methylenecyclopropane analogues of nucleosides
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7 January 2021
Cytomegalovirus retinitis in the era of highly active antiretroviral therapy
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based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.VIRUSRES.2010.11.004
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PMCID
3068221
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PubMed ID
21095209
1 reference
stated in
Europe PubMed Central
PMCID
3068221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21095209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
ResearchGate publication ID
49626411
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