(Q37814048)

23 August 2017

1 reference

title

Animal models of nonalcoholic fatty liver disease (English)

1 reference

metabolic dysfunction–associated steatotic liver disease

23 August 2017

0 references

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21119613

18 November 2024

1

Lionel Hebbard

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21119613

18 November 2024

2

Jacob George

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21119613

18 November 2024

language of work or name

English

0 references

publication date

30 November 2010

1 reference

full work available at URL

23 August 2017

http://www.nature.com/articles/nrgastro.2010.191

1 reference

https://api.crossref.org/works/10.1038/NRGASTRO.2010.191

http://www.nature.com/articles/nrgastro.2010.191.pdf

18 November 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/NRGASTRO.2010.191

Nature Reviews Gastroenterology & Hepatology

18 November 2024

published in

1 reference

23 August 2017

volume

8

1 reference

23 August 2017

issue

1

1 reference

23 August 2017

page(s)

35-44

1 reference

Recent advances in nonalcoholic fatty liver disease

23 August 2017

cites work

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Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production

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Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

31 March 2020

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Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

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Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.

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The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance

31 March 2020

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Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

31 March 2020

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Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation

31 March 2020

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CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

31 March 2020

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Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice

31 March 2020

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Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis

31 March 2020

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Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice

31 March 2020

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Curcumin inhibits NF-kappaB activation and reduces the severity of experimental steatohepatitis in mice

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

COX-2 induction in mice with experimental nutritional steatohepatitis: Role as pro-inflammatory mediator

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Intrahepatic insulin resistance in a murine model of steatohepatitis: effect of PPARgamma agonist pioglitazone

31 March 2020

1 reference

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Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet

31 March 2020

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Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

JNK1 but not JNK2 promotes the development of steatohepatitis in mice

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Endogenous liver carcinogenesis in the rat.

31 March 2020

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Comparative changes in the liver of female Fischer-344 rats after short-term feeding of a semipurified or a semisynthetic L-amino acid-defined choline-deficient diet

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Model of nonalcoholic steatohepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Steatohepatitis induced by intragastric overfeeding in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

High-fat emulsion-induced rat model of nonalcoholic steatohepatitis

31 March 2020

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A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet.

31 March 2020

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Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies

31 March 2020

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Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

31 March 2020

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The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome.

31 March 2020

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Mild hepatic fibrosis in cholesterol and sodium cholate diet-fed rats

31 March 2020

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Variation in susceptibility to atherosclerosis among inbred strains of mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Fructose consumption as a risk factor for non-alcoholic fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Possible involvement and the mechanisms of excess trans-fatty acid consumption in severe NAFLD in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Pathogenesis of NASH: animal models

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Obesity and the role of adipose tissue in inflammation and metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Adiponectin knockout mice on high fat diet develop fibrosing steatohepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Adiponectin deficiency promotes the production of inflammatory mediators while severely exacerbating hepatic injury in mice with polymicrobial sepsis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

A central role for JNK in obesity and insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Improved insulin sensitivity in high fat- and high cholesterol-fed Ldlr-/- mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: role of macrophage inflammation and infiltration into adipose tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Toll-like receptors and adaptor molecules in liver disease: update

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Patatin-like phospholipase domain-containing 3 and the pathogenesis and progression of pediatric nonalcoholic fatty liver disease

31 March 2020

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Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Overexpression of apolipoprotein CIII increases and CETP reverses diet-induced obesity in transgenic mice.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2010.191

Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions

31 March 2020

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12 December 2020

Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis.

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12 December 2020

Non-alcoholic steatohepatitis: definitions and pathogenesis

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12 December 2020

Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease

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Alcoholic liver disease: morphological manifestations. Review by an international group

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2

55

434

J Ludwig

1980

1 reference

https://api.crossref.org/works/10.1038/NRGASTRO.2010.191

18 November 2024

Identifiers

1 reference

Dimensions Publication ID

23 August 2017

1027849952

0 references

1 reference