(Q46865809)

25 December 2017

title

JNK1 but not JNK2 promotes the development of steatohepatitis in mice (English)

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25 December 2017

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Jörn M Schattenberg

1

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author name string

Rajat Singh

2

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25 December 2017

Yongjun Wang

3

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25 December 2017

Jay H Lefkowitch

4

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25 December 2017

Raina M Rigoli

5

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25 December 2017

Philipp E Scherer

6

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25 December 2017

Mark J Czaja

7

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25 December 2017

language of work or name

English

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publication date

1 January 2006

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25 December 2017

published in

Hepatology

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25 December 2017

volume

43

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25 December 2017

issue

1

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25 December 2017

page(s)

163-172

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25 December 2017

Nonalcoholic fatty liver disease

cites work

1 reference

7 January 2021

Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference

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7 January 2021

Steatohepatitis: a tale of two "hits"?

1 reference

7 January 2021

Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome

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7 January 2021

Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis

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7 January 2021

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

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7 January 2021

Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities

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7 January 2021

Pivotal role of superoxide anion and beneficial effect of antioxidant molecules in murine steatohepatitis.

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7 January 2021

Liver injury in the setting of steatosis: crosstalk between adipokine and cytokine

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7 January 2021

Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-alpha

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7 January 2021

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

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7 January 2021

Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice

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7 January 2021

Adiponectin acts in the brain to decrease body weight.

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7 January 2021

Beyond insulin resistance in NASH: TNF-alpha or adiponectin?

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7 January 2021

A central role for JNK in obesity and insulin resistance

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7 January 2021

The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death

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7 January 2021

Signal transduction by the JNK group of MAP kinases

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7 January 2021

NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun

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7 January 2021

Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes

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7 January 2021

c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation

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7 January 2021

Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expression

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7 January 2021

Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

1 reference

7 January 2021

Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.

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7 January 2021

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

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7 January 2021

Defective T Cell Differentiation in the Absence of Jnk1

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7 January 2021

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

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7 January 2021

The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance

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7 January 2021

Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation

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7 January 2021

Curcumin inhibits NF-kappaB activation and reduces the severity of experimental steatohepatitis in mice

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7 January 2021

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

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7 January 2021

Metformin reverses fatty liver disease in obese, leptin-deficient mice

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7 January 2021

Mitogen-activated protein kinase cascades as regulators of stress responses

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7 January 2021

JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways

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7 January 2021

JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine

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7 January 2021

c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis

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7 January 2021

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

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7 January 2021

The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase.

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7 January 2021

Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling

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7 January 2021

Orchestrating the unfolded protein response in health and disease

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7 January 2021

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

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7 January 2021

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

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7 January 2021

Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide

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7 January 2021

Identifiers

DOI

10.1002/HEP.20999

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25 December 2017

PubMed ID

16374858

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25 December 2017