(Q37821550)

23 August 2017

1 reference

title

Assays for α-synuclein aggregation (English)

1 reference

23 August 2017

1 reference

3

1 reference

23 August 2017

Lise Giehm

1

1 reference

23 August 2017

Nikolai Lorenzen

series ordinal

2

1 reference

23 August 2017

publication date

14 December 2010

1 reference

23 August 2017

1 reference

23 August 2017

volume

53

1 reference

23 August 2017

issue

3

1 reference

23 August 2017

page(s)

295-305

1 reference

Protein misfolding, functional amyloid, and human disease

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Role of Escherichia coli curli operons in directing amyloid fiber formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloidogenic nature of spider silk

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Functional amyloids signal their arrival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloids: not only pathological agents but also ordered nanomaterials

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Identification of two distinct synucleins from human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

A new method for purification of recombinant human alpha-synuclein in Escherichia coli.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

A kinetic study of beta-lactoglobulin amyloid fibril formation promoted by urea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Formation and seeding of amyloid fibrils from wild-type hen lysozyme and a peptide fragment from the β-domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid-like fibril formation in an all beta-barrel protein. Partially structured intermediate state(s) is a precursor for fibril formation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

An NMR investigation of solution aggregation reactions preceding the misassembly of acid-denatured cold shock protein A into fibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Engineering of betabellin-15D: a 64 residue beta sheet protein that forms long narrow multimeric fibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid fibrils from muscle myoglobin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid fibril formation by a helical cytochrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Solution conditions can promote formation of either amyloid protofilaments or mature fibrils from the HypF N-terminal domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Conversion of yeast phosphoglycerate kinase into amyloid-like structure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid fibrillogenesis: themes and variations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Interconverting conformations of variants of the human amyloidogenic protein beta2-microglobulin quantitatively characterized by dynamic capillary electrophoresis and computer simulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Modulation of S6 fibrillation by unfolding rates and gatekeeper residues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Toward understanding insulin fibrillation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid formation of a protein in the absence of initial unfolding and destabilization of the native state.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Polyglutamine expansion in ataxin-3 does not affect protein stability: implications for misfolding and disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Formation of insulin amyloid fibrils followed by FTIR simultaneously with CD and electron microscopy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Sulfates dramatically stabilize a salt-dependent type of glucagon fibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

What does it mean to be natively unfolded?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Conformational constraints for amyloid fibrillation: the importance of being unfolded

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Preparation of synthetic human islet amyloid polypeptide (IAPP) in a stable conformation to enable study of conversion to amyloid-like fibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Kinetic partitioning between aggregation and vesicle permeabilization by modified ADan

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

In vitro polymerization of a functional Escherichia coli amyloid protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Natively unfolded proteins: a point where biology waits for physics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Residual structure, backbone dynamics, and interactions within the synuclein family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Evidence for a partially folded intermediate in alpha-synuclein fibril formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Structural characterization of alpha-synuclein in an aggregation prone state.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

SDS-induced fibrillation of alpha-synuclein: an alternative fibrillation pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Mechanism of amyloidogenesis: nucleation-dependent fibrillation versus double-concerted fibrillation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Dependence of alpha-synuclein aggregate morphology on solution conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

The kinetics of nucleated polymerizations at high concentrations: amyloid fibril formation near and above the "supercritical concentration".

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Accelerated fibrillation of alpha-synuclein induced by the combined action of macromolecular crowding and factors inducing partial folding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Polycation-induced oligomerization and accelerated fibrillation of human alpha-synuclein in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Nuclear localization of alpha-synuclein and its interaction with histones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Accelerated alpha-synuclein fibrillation in crowded milieu

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Concerted action of metals and macromolecular crowding on the fibrillation of alpha-synuclein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Molecular crowding accelerates fibrillization of alpha-synuclein: could an increase in the cytoplasmic protein concentration induce Parkinson's disease?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Lipid binding inhibits alpha-synuclein fibril formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Nucleated conformational conversion and the replication of conformational information by a prion determinant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Structural basis for cyclodextrins' suppression of human growth hormone aggregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Physical, morphological and functional differences between ph 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide Abeta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

The changing face of glucagon fibrillation: structural polymorphism and conformational imprinting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Fluorescent N-arylaminonaphthalene sulfonate probes for amyloid aggregation of alpha-synuclein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Sensitive fluorescence polarization technique for rapid screening of alpha-synuclein oligomerization/fibrillization inhibitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Cellular polyamines promote the aggregation of alpha-synuclein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Strategies to increase the reproducibility of protein fibrillization in plate reader assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Screening for ligands using a generic and high-throughput light-scattering-based assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

A SAXS study of glucagon fibrillation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

An analytical solution to the kinetics of breakable filament assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid formation in surfactants and alcohols: membrane mimetics or structural switchers?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Conformational behavior and aggregation of alpha-synuclein in organic solvents: modeling the effects of membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid fibril formation by a partially structured intermediate state of alpha-chymotrypsin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid fibril formation by human stefin B: influence of pH and TFE on fibril growth and morphology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Amyloid fibril formation can proceed from different conformations of a partially unfolded protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Mechanism by which the amyloid-like fibrils of a beta 2-microglobulin fragment are induced by fluorine-substituted alcohols

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Forcing nonamyloidogenic beta-synuclein to fibrillate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Characterization of seed nuclei in glucagon aggregation using light scattering methods and field-flow fractionation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Modeling proteasome dynamics in Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Proteasomal function is impaired in substantia nigra in Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

alpha-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

A fluorescent pentameric thiophene derivative detects in vitro-formed prefibrillar protein aggregates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

Studies on the in vitro assembly of a beta 1-40: implications for the search for a beta fibril formation inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.008

10.1016/J.YMETH.2010.12.008

7 January 2021

Identifiers

DOI

1 reference

23 August 2017

1 reference