(Q37825896)

23 August 2017

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title

c-FMS inhibitors: a patent review (English)

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23 August 2017

Christopher J Burns

1

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author name string

Andrew F Wilks

series ordinal

2

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23 August 2017

language of work or name

English

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publication date

5 January 2011

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Expert Opinion on Therapeutic Patents

23 August 2017

published in

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23 August 2017

volume

21

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23 August 2017

issue

2

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23 August 2017

page(s)

147-165

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The PDGF family: four gene products form five dimeric isoforms

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Identification of a ligand for the c-kit proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Pyrido[2,3-d]pyrimidin-5-ones: a novel class of antiinflammatory macrophage colony-stimulating factor-1 receptor inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Colony-stimulating factor-1 in immunity and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Macrophage colony stimulating factor: not just for macrophages anymore! A gateway into complex biologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

M-CSF: a novel plasmacytoid and conventional dendritic cell poietin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCE

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Langerhans cells arise from monocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Microglia: activation and their significance in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Intracellular signaling in M-CSF-induced microglia activation: role of Iba1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Osteopetrotic (op/op) mice have reduced microglia, no Abeta deposition, and no changes in dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Osteoclasts: what do they do and how do they do it?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Raised concentrations of macrophage colony stimulating factor in severe unstable angina beyond the acute phase are strongly predictive of long term outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Amplification of inflammation in emphysema and its association with latent adenoviral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Macrophage colony-stimulating factor expression and macrophage accumulation in renal allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

The relationship between disease activity, joint destruction, and functional capacity over the course of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: implications for the role of cytokines in cartilage destruction and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Production of macrophage colony-stimulating factor (M-CSF) by human articular cartilage and chondrocytes. Modulation by interleukin-1 and tumor necrosis factor alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Rheumatoid synovial endothelial cells produce macrophage colony-stimulating factor leading to osteoclastogenesis in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

M-CSF mediates TNF-induced inflammatory osteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

1,25-Dihydroxyvitamin D3 hypersensitivity of osteoclast precursors from patients with Paget's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Osteoclast differentiation from circulating mononuclear precursors in Paget's disease is hypersensitive to 1,25-dihydroxyvitamin D(3) and RANKL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Genetic linkage of Paget disease of the bone to chromosome 18q

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Paget disease of bone: mapping of two loci at 5q35-qter and 5q31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Paget's disease of bone: evidence for a susceptibility locus on chromosome 18q and for genetic heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Macrophages regulate the angiogenic switch in a mouse model of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

CSF-1 and its receptor in ovarian, endometrial and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

CSF-1 and its receptor in breast carcinomas and neoplasms of the female reproductive tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Increased serum levels of macrophage colony-stimulating factor in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Standardizing cancer biomarkers criteria: data elements as a foundation for a database. Inflammatory mediator/M-CSF as model marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Tumour-educated macrophages promote tumour progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Distinct role of macrophages in different tumor microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Colony-stimulating factor-1 receptor inhibitors for the treatment of cancer and inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Discovery of 2-(alpha-methylbenzylamino) pyrazines as potent Type II inhibitors of FMS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

The orally-active and selective c-Fms tyrosine kinase inhibitor Ki20227 inhibits disease progression in a collagen-induced arthritis mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

The selective M-CSF receptor tyrosine kinase inhibitor Ki20227 suppresses experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Synthesis of novel anilinoquinolines as c-fms inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Identification of 3-amido-4-anilinoquinolines as potent and selective inhibitors of CSF-1R kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

3-amido-4-anilinoquinolines as CSF-1R kinase inhibitors 2: Optimization of the PK profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Inhibition of phosphorylation of the colony-stimulating factor-1 receptor (c-Fms) tyrosine kinase in transfected cells by ABT-869 and other tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Discovery of a new potent bisamide FMS kinase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Synthesis and evaluation of novel 3,4,6-substituted 2-quinolones as FMS kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

The (un)targeted cancer kinome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Rational design of inhibitors that bind to inactive kinase conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

Biochemical mechanisms of drug action: what does it take for success?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

p50 Nuclear Factor- B Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.545348

10.1517/13543776.2011.545348

21 January 2018

Identifiers

DOI

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23 August 2017

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