(Q37839120)

24 August 2017

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title

Biological signalling activity measurements using mass spectrometry (English)

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24 August 2017

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Pedro R Cutillas

1

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24 August 2017

Claus Jørgensen

series ordinal

2

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24 August 2017

language of work or name

English

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publication date

1 March 2011

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24 August 2017

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24 August 2017

434

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24 August 2017

2

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24 August 2017

189-199

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describes a project that uses

24 August 2017

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Evolution of protein kinase signaling from yeast to man

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

PI3K: downstream AKTion blocks apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

MAP kinases: charting the regulatory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

AMP-activated protein kinase signaling in metabolic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Targeting innate immunity protein kinase signalling in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Exploiting the PI3K/AKT pathway for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Regulation of Raf-Akt Cross-talk

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101974

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Molecular crosstalk between p70S6k and MAPK cell signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Cell signaling pathways as control modules: complexity for simplicity?

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101974

Cell-signalling dynamics in time and space

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101974

Ultrasensitivity in the mitogen-activated protein kinase cascade

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101974

Robustness of cellular functions

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101974

Emergent properties of networks of biological signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101974

Simplistic pathways or complex networks?

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101974

A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Positive selection of tyrosine loss in metazoan evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Dynamic modularity in protein interaction networks predicts breast cancer outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

KESTREL: a powerful method for identifying the physiological substrates of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

A global protein kinase and phosphatase interaction network in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Cell fate decisions are specified by the dynamic ERK interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Challenges and opportunities in defining the essential cancer kinome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Targeted therapies in breast cancer: where are we now?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Flying under the radar: the new wave of BCR-ABL inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Kinase requirements in human cells: I. Comparing kinase requirements across various cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Kinase requirements in human cells: IV. Differential kinase requirements in cervical and renal human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Cancer proliferation gene discovery through functional genomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Patterns of somatic mutation in human cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Genomic screening with RNAi: results and challenges

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101974

Quantification of protein kinase activities by LC-MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Synthesis and function of 3-phosphorylated inositol lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

The synthetic peptide RPRAATF allows specific assay of Akt activity in cell lysates

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Sensitive multiplexed analysis of kinase activities and activity-based kinase identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Linear Motif Atlas for Phosphorylation-Dependent Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Approaches and applications of quantitative LC-MS for proteomics and activitomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Tracing pathway activities with kinase inhibitors and reverse phase protein arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

AKT/PKB signaling: navigating downstream

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Weak functional constraints on phosphoproteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Increased confidence in large-scale phosphoproteomics data by complementary mass spectrometric techniques and matching of phosphopeptide data sets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

NetworKIN: a resource for exploring cellular phosphorylation networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Targets of the cyclin-dependent kinase Cdk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

QIKS--Quantitative identification of kinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Global and site-specific quantitative phosphoproteomics: principles and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Overview of quantitative LC-MS techniques for proteomics and activitomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Analytical strategies for phosphoproteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Quantitative proteomics to study mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Profiling of UV-induced ATM/ATR signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Quantification of gel-separated proteins and their phosphorylation sites by LC-MS using unlabeled internal standards: analysis of phosphoprotein dynamics in a B cell lymphoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Dissection of the insulin signaling pathway via quantitative phosphoproteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Phospho.ELM: a database of phosphorylation sites--update 2008.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Tranche distributed repository and ProteomeCommons.org

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Proteomics data repositories: providing a safe haven for your data and acting as a springboard for further research

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Application of label-free quantitative peptidomics for the identification of urinary biomarkers of kidney chronic allograft dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Increased selectivity, analytical precision, and throughput in targeted proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Quantitative profile of five murine core proteomes using label-free functional proteomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

Applying a targeted label-free approach using LC-MS AMT tags to evaluate changes in protein phosphorylation following phosphatase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

A self-validating quantitative mass spectrometry method for assessing the accuracy of high-content phosphoproteomic experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

21 January 2018

Drivers and passengers

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101974

21 January 2018

Identifiers

DOI

10.1042/BJ20101974

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24 August 2017

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