(Q37844011)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

review article

1 reference

title

Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

5

Elmar Heinzle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Carl-Fredrik Mandenius

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Daniella Steel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Thomas Meyer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Julia Asp

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Sarina Arain

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Udo Kraushaar

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Susanne Bremer

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Reiner Class

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Peter Sartipy

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

16 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

Journal of Applied Toxicology

22 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

191-205

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

22 January 2020

cites work

1 reference

Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture

21 January 2018

1 reference

Transgenic enrichment of cardiomyocytes from human embryonic stem cells

21 January 2018

1 reference

Assaying cardiac biomarkers for toxicity testing using biosensing and cardiomyocytes derived from human embryonic stem cells

21 January 2018

1 reference

Monitoring of troponin release from cardiomyocytes during exposure to toxic substances using surface plasmon resonance biosensing

21 January 2018

1 reference

High throughput, non-invasive and dynamic toxicity screening on adherent cells using respiratory measurements.

21 January 2018

1 reference

Functional and developmental properties of human embryonic stem cells-derived cardiomyocytes

21 January 2018

1 reference

Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes

21 January 2018

1 reference

beta(1)- and beta(2)-adrenoceptor responses in cardiomyocytes derived from human embryonic stem cells: comparison with failing and non-failing adult human heart

21 January 2018

1 reference

Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability

21 January 2018

1 reference

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

21 January 2018

1 reference

In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes

21 January 2018

1 reference

Evidences of the gender-related differences in cardiac repolarization and the underlying mechanisms in different animal species and human

21 January 2018

1 reference

Controlled-size embryoid body formation in concave microwell arrays

21 January 2018

1 reference

Microplates with integrated oxygen sensors for kinetic cell respiration measurement and cytotoxicity testing in primary and secondary cell lines

21 January 2018

1 reference

Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction

21 January 2018

1 reference

Derivation of a xeno-free human embryonic stem cell line

21 January 2018

1 reference

Fluorescent cell-based sensing approaches for toxicity testing

21 January 2018

1 reference

A cell-based sensor system for toxicity testing using multiwavelength fluorescence spectroscopy

21 January 2018

1 reference

Human embryonic stem cells carrying mutations for severe genetic disorders

21 January 2018

1 reference

Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts

21 January 2018

1 reference

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK.

21 January 2018

1 reference

Nongenetic method for purifying stem cell-derived cardiomyocytes

21 January 2018

1 reference

Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization

21 January 2018

1 reference

Identification and selection of cardiomyocytes during human embryonic stem cell differentiation

21 January 2018

1 reference

Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors

21 January 2018

1 reference

Improvement of cardiac efficacy and safety models in drug discovery by the use of stem cell-derived cardiomyocytes

21 January 2018

1 reference

Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes.

21 January 2018

1 reference

Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

21 January 2018

1 reference

Profiling substrate fluxes in the isolated working mouse heart using 13C-labeled substrates: focusing on the origin and fate of pyruvate and citrate carbons

21 January 2018

1 reference

Non-cardiomyocytes influence the electrophysiological maturation of human embryonic stem cell-derived cardiomyocytes during differentiation

21 January 2018

1 reference

Role of the transverse-axial tubule system in generating calcium sparks and calcium transients in rat atrial myocytes

21 January 2018

1 reference

Can the pharmaceutical industry reduce attrition rates?

21 January 2018

1 reference

Methods for inducing embryoid body formation: in vitro differentiation system of embryonic stem cells

21 January 2018

1 reference

Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts

21 January 2018

1 reference

Timing of new black box warnings and withdrawals for prescription medications

21 January 2018

1 reference

Drug withdrawals from the Canadian market for safety reasons, 1963-2004.

21 January 2018

1 reference

Species plays an important role in drug-induced prolongation of action potential duration and early afterdepolarizations in isolated Purkinje fibers

21 January 2018

1 reference

The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells

21 January 2018

1 reference

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

21 January 2018

1 reference

Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2.

21 January 2018

1 reference

Metabolic flux analysis in eukaryotes

21 January 2018

1 reference

An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using Hep G2 cells

21 January 2018

1 reference

Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs

21 January 2018

1 reference

Respirometric Screening Technology for ADME-Tox studies.

21 January 2018

1 reference

Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures

21 January 2018

1 reference

Substantial variation in the cardiac differentiation of human embryonic stem cell lines derived and propagated under the same conditions--a comparison of multiple cell lines.

21 January 2018

1 reference

The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes

21 January 2018

1 reference

Cardiac effects of MDMA on the metabolic profile determined with 1H-magnetic resonance spectroscopy in the rat.

21 January 2018

1 reference

Mechanisms of drug induced QT interval prolongation.

21 January 2018

1 reference

A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells

21 January 2018

1 reference

Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

21 January 2018

1 reference

Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511.

21 January 2018

1 reference

Human embryonic stem cells as a model for studying epigenetic regulation during early development.

21 January 2018

1 reference

Cardiomyocyte enrichment from human embryonic stem cell cultures by selection of ALCAM surface expression.

21 January 2018

1 reference

Designing synthetic materials to control stem cell phenotype

21 January 2018

1 reference

Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach.

21 January 2018

1 reference

Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes

21 January 2018

1 reference

1,4,5-Inositol trisphosphate-operated intracellular Ca(2+) stores and angiotensin-II/endothelin-1 signaling pathway are functional in human embryonic stem cell-derived cardiomyocytes

21 January 2018

1 reference

The effect of mechanical loads in the differentiation of precursor cells into mature cells

21 January 2018

1 reference

Assessment of the ultrastructural and proliferative properties of human embryonic stem cell-derived cardiomyocytes

21 January 2018

1 reference

Molecular signature of cardiomyocyte clusters derived from human embryonic stem cells.

21 January 2018

1 reference

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

Embryonic stem cell lines derived from human blastocysts

21 January 2018

1 reference

Reducing QT liability and proarrhythmic risk in drug discovery and development

21 January 2018

1 reference

Identification of cell surface proteins for antibody-based selection of human embryonic stem cell-derived cardiomyocytes.

21 January 2018

1 reference

Foetal and adult cardiomyocyte progenitor cells have different developmental potential

21 January 2018

1 reference

Metabolic flux screening of Saccharomyces cerevisiae single knockout strains on glucose and galactose supports elucidation of gene function

21 January 2018

1 reference

Differentiation of human embryonic stem cells to cardiomyocytes for in vitro and in vivo applications

21 January 2018

1 reference

Synthetic polymer coatings for long-term growth of human embryonic stem cells.

21 January 2018

1 reference

Isotopomer analysis of myocardial substrate metabolism: a systems biology approach

21 January 2018

1 reference

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

21 January 2018

1 reference

Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and function

21 January 2018

1 reference

Bidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments.

21 January 2018

1 reference

Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis.

21 January 2018

1 reference

Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells

21 January 2018

1 reference

Hybrid optimization for 13C metabolic flux analysis using systems parametrized by compactification

21 January 2018

1 reference

Enhanced differentiation of human embryonic stem cells into cardiomyocytes by combining hanging drop culture and 5-azacytidine treatment

21 January 2018

1 reference

Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

1 reference

Control of the cardiac action potential: The role of repolarization dynamics.

21 January 2018

1 reference

Functional cardiomyocytes derived from human induced pluripotent stem cells

21 January 2018

1 reference

Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JAT.1663

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21328588%20AND%20SRC:MED&resulttype=core&format=json

release_tmzno4bl7zg3bcdkk4nmsadzje

22 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tmzno4bl7zg3bcdkk4nmsadzje

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference