(Q37847125)

24 August 2017

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title

Neuropeptide Y receptors: ligand binding and trafficking suggest novel approaches in drug development (English)

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Annette Gabriele Beck-Sickinger

24 August 2017

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series ordinal

3

object named as

Annette G Beck-Sickinger

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24 August 2017

2

Karin Mörl

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24 August 2017

Cornelia Walther

1

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24 August 2017

publication date

24 February 2011

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Journal of Peptide Science

24 August 2017

published in

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24 August 2017

volume

17

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24 August 2017

issue

4

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24 August 2017

page(s)

233-246

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Molecular characterization of the ligand-receptor interaction of the neuropeptide Y family

24 August 2017

cites work

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Therapeutic potential of neuropeptide Y (NPY) receptor ligands.

21 January 2018

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21 January 2018

NPY and cardiac diseases

1 reference

Relevance of the neuropeptide Y system in the biology of cancer progression.

21 January 2018

1 reference

21 January 2018

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Beta-arrestin-biased ligands at seven-transmembrane receptors

21 January 2018

1 reference

Teaching old receptors new tricks: biasing seven-transmembrane receptors

21 January 2018

1 reference

X-ray analysis (1. 4-A resolution) of avian pancreatic polypeptide: Small globular protein hormone

21 January 2018

1 reference

21 January 2018

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Solution structure of human neuropeptide Y

21 January 2018

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Biophysical methods to study ligand-receptor interactions of neuropeptide Y

21 January 2018

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The neuropeptide Y monomer in solution is not folded in the pancreatic-polypeptide fold

21 January 2018

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Distribution of pancreatic polypeptide and peptide YY

21 January 2018

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The role of gut hormones in the regulation of body weight and energy homeostasis

21 January 2018

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The pancreatic polypeptide (PP-fold) family: gastrointestinal, vascular, and feeding behavioral implications

21 January 2018

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Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides

21 January 2018

1 reference

Peptide YY: food for thought.

21 January 2018

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The role of peptide YY in appetite regulation and obesity.

21 January 2018

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The role of PYY in feeding regulation

21 January 2018

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Peptide YY and appetite control

21 January 2018

1 reference

Neuropeptide Y: complete amino acid sequence of the brain peptide

21 January 2018

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Neuropeptide Y: the universal soldier

21 January 2018

1 reference

Cloning, characterization, and DNA sequence of a human cDNA encoding neuropeptide tyrosine

21 January 2018

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Neuropeptide Y family of peptides: structure, anatomical expression, function, and molecular evolution

21 January 2018

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Evidence for different pre-and post-junctional receptors for neuropeptide Y and related peptides

21 January 2018

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NPY and cohorts in regulating appetite, obesity and metabolic syndrome: beneficial effects of gene therapy.

21 January 2018

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Subtypes of receptors for neuropeptide Y: implications for the targeting of therapeutics

21 January 2018

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Neuropeptide Y co-exists and co-operates with noradrenaline in perivascular nerve fibers

21 January 2018

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Neuropeptides and their receptors: innovative science providing novel therapeutic targets

21 January 2018

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Multiple neuropeptide Y receptors are involved in cardiovascular regulation. Peripheral and central mechanisms

21 January 2018

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The role of neuropeptide Y in cardiovascular regulation

21 January 2018

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21 January 2018

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NPY and its involvement in axon guidance, neurogenesis, and feeding

21 January 2018

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Neuropeptide Y (NPY) in alcohol intake and dependence.

21 January 2018

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A role for neuropeptide Y in neurobiological responses to ethanol and drugs of abuse

21 January 2018

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The NPY system in stress, anxiety and depression

21 January 2018

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A possible role of neuropeptide Y in depression and stress

21 January 2018

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Effects of neuropeptide Y on short-term memory.

21 January 2018

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Molecular recognition of the NPY hormone family by their receptors

21 January 2018

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Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues

21 January 2018

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NPY and pain as seen from the histochemical side

21 January 2018

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Behavioral profiling of NPY in aggression and neuropsychiatric diseases

21 January 2018

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NPY and receptors in immune and inflammatory diseases.

21 January 2018

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The year in G protein-coupled receptor research

21 January 2018

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Target validation of G-protein coupled receptors

21 January 2018

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Distribution of NPY receptors in the hypothalamus

21 January 2018

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Cloned human neuropeptide Y receptor couples to two different second messenger systems

21 January 2018

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Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides

21 January 2018

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Novel analogues of neuropeptide Y with a preference for the Y1-receptor

21 January 2018

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[Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist

21 January 2018

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First selective agonist of the neuropeptide Y1-receptor with reduced size

21 January 2018

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Ala31-Aib32: identification of the key motif for high affinity and selectivity of neuropeptide Y at the Y5-receptor.

21 January 2018

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[D-Trp(34)] neuropeptide Y is a potent and selective neuropeptide Y Y(5) receptor agonist with dramatic effects on food intake

21 January 2018

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The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats

21 January 2018

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The anti-epileptic actions of neuropeptide Y in the hippocampus are mediated by Y and not Y receptors

21 January 2018

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Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY

21 January 2018

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Cloning and Functional Expression of a Human Y4 Subtype Receptor for Pancreatic Polypeptide, Neuropeptide Y, and Peptide YY

21 January 2018

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Molecular identification of the long isoform of the human neuropeptide Y Y5 receptor and pharmacological comparison with the short Y5 receptor isoform

21 January 2018

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A receptor subtype involved in neuropeptide-Y-induced food intake

21 January 2018

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Neuropeptide Y receptors; antisecretory control of intestinal epithelial function

21 January 2018

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Complete L-alanine scan of neuropeptide Y reveals ligands binding to Y1 and Y2 receptors with distinguished conformations

21 January 2018

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Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands.

21 January 2018

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Re-evaluation of receptor-ligand interactions of the human neuropeptide Y receptor Y1: a site-directed mutagenesis study

21 January 2018

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Mutagenesis of human neuropeptide Y/peptide YY receptor Y2 reveals additional differences to Y1 in interactions with highly conserved ligand positions

21 January 2018

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GPC receptors and not ligands decide the binding mode in neuropeptide Y multireceptor/multiligand system.

21 January 2018

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Rapid internalization and recycling of the human neuropeptide Y Y(1) receptor

21 January 2018

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Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor

21 January 2018

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Signaling by internalized G-protein-coupled receptors.

21 January 2018

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Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors

21 January 2018

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G protein-coupled receptor sorting to endosomes and lysosomes

21 January 2018

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Agonist induced receptor internalization of neuropeptide Y receptor subtypes depends on third intracellular loop and C-terminus

21 January 2018

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Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling

21 January 2018

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Agonist- and antagonist-induced sequestration/internalization of neuropeptide Y Y1 receptors in HEK293 cells

21 January 2018

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Monitoring of the internalization of neuropeptide Y on neuroblastoma cell line SK-N-MC.

21 January 2018

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Cloned neuropeptide Y (NPY) Y1 and pancreatic polypeptide Y4 receptors expressed in Chinese hamster ovary cells show considerable agonist-driven internalization, in contrast to the NPY Y2 receptor

21 January 2018

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The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced beta-arrestin 2 interaction

21 January 2018

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Distinct motifs of neuropeptide Y receptors differentially regulate trafficking and desensitization

21 January 2018

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Role of the C terminus in neuropeptide Y Y1 receptor desensitization and internalization

21 January 2018

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Quantitative analysis of neuropeptide Y receptor association with beta-arrestin2 measured by bimolecular fluorescence complementation.

21 January 2018

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Contribution of a tyrosine-based motif to cellular trafficking of wild-type and truncated NPY Y1 receptors

21 January 2018

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A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors

21 January 2018

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Ligand-induced internalization and recycling of the human neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail

21 January 2018

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Ligand internalization by cloned neuropeptide Y Y5 receptors excludes Y2 and Y4 receptor-selective peptides

21 January 2018

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Radiometal targeted tumor diagnosis and therapy with peptide hormones

21 January 2018

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High-affinity neuropeptide Y receptor antagonists

21 January 2018

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[(125)I]-GR231118: a high affinity radioligand to investigate neuropeptide Y Y(1) and Y(4) receptors

21 January 2018

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Highly selective and potent neuropeptide Y (NPY) Y1 receptor antagonists based on [Pro(30), Tyr(32), Leu(34)]NPY(28-36)-NH2 (BW1911U90).

21 January 2018

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The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226.

21 January 2018

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Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults

21 January 2018

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The Novel Neuropeptide Y Y5 Receptor Antagonist Lu AA33810 [N-[[trans-4-[(4,5-Dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] Exerts Anxiolytic- and Antidepressant-Like Effects in Rat Models of Stress …

21 January 2018

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BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist

21 January 2018

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Tolerance to ethanol sedation and withdrawal hyper-excitability is mediated via neuropeptide Y Y1 and Y5 receptors.

21 January 2018

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Neuropeptide Y modulates steroid production of human adrenal H295R cells through Y1 receptors

21 January 2018

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Novel carbazole derivatives as NPY Y1 antagonists

21 January 2018

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Synthesis and evaluation of a series of 2,4-diaminopyridine derivatives as potential positron emission tomography tracers for neuropeptide Y Y1 receptors

21 January 2018

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Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activity

21 January 2018

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Effects of a selective neuropeptide Y Y2 receptor antagonist, BIIE0246, on Y2 receptors at peripheral neuroeffector junctions

21 January 2018

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Anxiolytic-like effect of the selective neuropeptide Y Y2 receptor antagonist BIIE0246 in the elevated plus-maze

21 January 2018

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Irreversible binding kinetics of neuropeptide Y ligands to Y2 but not to Y1 and Y5 receptors

21 January 2018

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Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening

21 January 2018

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Novel non-peptidic neuropeptide Y Y2 receptor antagonists

21 January 2018

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The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists.

21 January 2018

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Long-term pharmacotherapy for obesity

21 January 2018

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Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis

21 January 2018

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Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig

21 January 2018

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Neuropeptide Y receptor(s) mediating feeding in the rat: characterization with antagonists.

21 January 2018

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Effects of a novel Y5 antagonist in obese mice: combination with food restriction or sibutramine

21 January 2018

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Design, syntheses, and structure-activity relationships of novel NPY Y5 receptor antagonists: 2-{3-Oxospiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl}benzimidazole derivatives

21 January 2018

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Discovery of novel orally active ureido NPY Y5 receptor antagonists

21 January 2018

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Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.

21 January 2018

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Identification and characterization of pseudoirreversible nonpeptide antagonists of the neuropeptide Y Y5 receptor and development of a novel Y5-selective radioligand

21 January 2018

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Effect of peptide YY3-36 on food intake in humans

21 January 2018

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Peptide drugs to target G protein-coupled receptors

21 January 2018

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Modulation of neuropeptide Y receptors for the treatment of obesity

21 January 2018

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Comparison of independent and combined chronic anti-obese effects of NPY Y2 receptor agonist, PYY(3-36), and NPY Y5 receptor antagonist in diet-induced obese mice

21 January 2018

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Synergistic interaction between neuropeptide Y1 and Y5 receptor pathways in regulation of energy homeostasis.

21 January 2018

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NPY Y1 and Y5 receptor selective antagonists as anti-obesity drugs

21 January 2018

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Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors

21 January 2018

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Role of neuropeptide Y and its receptors in the progression of endocrine-related cancer.

21 January 2018

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Neuropeptide Y and its Y2 receptor: potential targets in neuroblastoma therapy

21 January 2018

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Constitutive neuropeptide Y Y(4) receptor expression in human colonic adenocarcinoma cell lines

21 January 2018

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Peptide receptors as molecular targets for cancer diagnosis and therapy

21 January 2018

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Novel peptide conjugates for tumor-specific chemotherapy

21 January 2018

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99mTc-labeled neuropeptide Y analogues as potential tumor imaging agents

21 January 2018

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Breast-cancer diagnosis by neuropeptide Y analogues: from synthesis to clinical application

21 January 2018

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Analogues of Neuropeptide Y Containing β-Aminocyclopropane Carboxylic Acids are the Shortest Linear Peptides That Are Selective for the Y1 Receptor

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PSC.1357

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24 August 2017

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