(Q37850700)

24 August 2017

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title

Maintenance of genomic integrity in hematopoietic stem cells (English)

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24 August 2017

2

Atsushi Hirao

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24 August 2017

Kazuhito Naka

1

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24 August 2017

9 March 2011

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International Journal of Hematology

24 August 2017

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24 August 2017

93

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24 August 2017

4

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24 August 2017

434-439

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https://scigraph.springernature.com/pub.10.1007/s12185-011-0793-z

24 August 2017

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cites work

A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

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12 December 2020

Regulation of DNA repair throughout the cell cycle

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12 December 2020

A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche

1 reference

12 December 2020

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

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12 December 2020

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

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12 December 2020

TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

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12 December 2020

mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization

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12 December 2020

p53-mediated hematopoietic stem and progenitor cell competition.

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12 December 2020

FOXO transcription factors at the interface between longevity and tumor suppression

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12 December 2020

Uncertainty in the niches that maintain haematopoietic stem cells

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12 December 2020

Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.

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12 December 2020

Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation

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12 December 2020

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

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12 December 2020

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

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12 December 2020

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

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12 December 2020

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

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12 December 2020

Regulation of hematopoiesis and its interaction with stem cell niches.

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12 December 2020

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

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12 December 2020

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

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12 December 2020

DNA repair is limiting for haematopoietic stem cells during ageing

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12 December 2020

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

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12 December 2020

Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells

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12 December 2020

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

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12 December 2020

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

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12 December 2020

Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.

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12 December 2020

Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity

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12 December 2020

mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion.

1 reference

12 December 2020

10.1007/S12185-011-0793-Z

Identifiers

DOI

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24 August 2017

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PubMed ID

21384097