(Q37851050)

24 August 2017

1 reference

title

Insights into the processing of MHC class I ligands gained from the study of human tumor epitopes (English)

1 reference

24 August 2017

Nathalie Vigneron

1

1 reference

PubMed ID

21387143

24 August 2017

Benoît J Van den Eynde

series ordinal

2

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24 August 2017

9 March 2011

1 reference

Cellular and Molecular Life Sciences

24 August 2017

1 reference

24 August 2017

68

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24 August 2017

1503-1520

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24 August 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1007/s00018-011-0658-x

24 August 2017

0 references

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Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

21 January 2018

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The majority of autologous cytolytic T-lymphocyte clones derived from peripheral blood lymphocytes of a melanoma patient recognize an antigenic peptide derived from gene Pmel17/gp100.

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High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens

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A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

21 January 2018

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The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas

21 January 2018

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A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas

21 January 2018

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A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma

21 January 2018

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BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes

21 January 2018

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A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma

21 January 2018

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Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor

21 January 2018

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Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes

21 January 2018

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HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation

21 January 2018

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Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins

21 January 2018

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Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes

21 January 2018

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A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3.

21 January 2018

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Human neoplasms elicit multiple specific immune responses in the autologous host

21 January 2018

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A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening

21 January 2018

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Identification of a meiosis-specific protein as a member of the class of cancer/testis antigens

21 January 2018

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Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library

21 January 2018

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LAGE-1, a new gene with tumor specificity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Cancer/testis antigen CSAGE is concurrently expressed with MAGE in chondrosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Structure, chromosomal localization, and expression of 12 genes of the MAGE family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A MAGE-A1 peptide is recognized on HLA-B7 human tumors by cytolytic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The 5-methylcytosine content of DNA from human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

SSX: a multigene family with several members transcribed in normal testis and human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The SSX gene family: characterization of 9 complete genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Two tyrosinase nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A ras-mutated peptide targeted by CTL infiltrating a human melanoma lesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Immunological characterization of missense mutations occurring within cytotoxic T cell-defined p53 epitopes in HLA-A*0201+ squamous cell carcinomas of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

T cells associated with tumor regression recognize frameshifted products of the CDKN2A tumor suppressor gene locus and a mutated HLA class I gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Survivin is a shared tumor-associated antigen expressed in a broad variety of malignancies and recognized by specific cytotoxic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Spontaneous human squamous cell carcinomas are killed by a human cytotoxic T lymphocyte clone recognizing a wild-type p53-derived peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Cytotoxic T-lymphocyte clones, established by stimulation with the HLA-A2 binding p5365-73 wild type peptide loaded on dendritic cells In vitro, specifically recognize and lyse HLA-A2 tumour cells overexpressing the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Identification of a highly immunogenic HLA-A*01-binding T cell epitope of WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Immunogenic (tum-) variants of mouse tumor P815: cloning of the gene of tum- antigen P91A and identification of the tum- mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Structure of the gene of tum- transplantation antigen P198: a point mutation generates a new antigenic peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

T cell-recognized antigenic peptides derived from the cellular genome are not protein degradation products but can be generated directly by transcription and translation of short subgenic regions. A hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A peptide recognized by human cytolytic T lymphocytes on HLA-A2 melanomas is encoded by an intron sequence of the N-acetylglucosaminyltransferase V gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Interleukin-2-induced, melanoma-specific T cells recognize CAMEL, an unexpected translation product of LAGE-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

An alternative open reading frame of the human macrophage colony-stimulating factor gene is independently translated and codes for an antigenic peptide of 14 amino acids recognized by tumor-infiltrating CD8 T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

MELOE-1 is a new antigen overexpressed in melanomas and involved in adoptive T cell transfer efficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

An additional ORF on meloe cDNA encodes a new melanoma antigen, MELOE-2, recognized by melanoma-specific T cells in the HLA-A2 context.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Identification of BING-4 cancer antigen translated from an alternative open reading frame of a gene in the extended MHC class II region using lymphocytes from a patient with a durable complete regression following immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Ribosomal scanning past the primary initiation codon as a mechanism for expression of CTL epitopes encoded in alternative reading frames

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A human minor histocompatibility antigen specific for B cell acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Presentation of out-of-frame peptide/MHC class I complexes by a novel translation initiation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Constitutive display of cryptic translation products by MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Unanticipated antigens: translation initiation at CUG with leucine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A distinct translation initiation mechanism generates cryptic peptides for immune surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A processed pseudogene codes for a new antigen recognized by a CD8(+) T cell clone on melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Degradation of cell proteins and the generation of MHC class I-presented peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Substrate access and processing by the 20S proteasome core particle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Structure of 20S proteasome from yeast at 2.4 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The structure of the mammalian 20S proteasome at 2.75 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Proteasome from Thermoplasma acidophilum: a threonine protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The multicatalytic proteinase complex, a major extralysosomal proteolytic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

PRE3, highly homologous to the human major histocompatibility complex-linked LMP2 (RING12) gene, codes for a yeast proteasome subunit necessary for the peptidylglutamyl-peptide hydrolyzing activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Mutations in the yeast proteasome beta-type subunit Pre3 uncover position-dependent effects on proteasomal peptidase activity and in vivo function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A MAGE-1 antigenic peptide recognized by human cytolytic T lymphocytes on HLA-A2 tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Production of an antigenic peptide by insulin-degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Molecular cloning of the mouse proteasome subunits MC14 and MECL-1: reciprocally regulated tissue expression of interferon-gamma-modulated proteasome subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

MHC class I expression in mice lacking the proteasome subunit LMP-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Differential processing of class-I-restricted epitopes by the standard proteasome and the immunoproteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The production of a new MAGE-3 peptide presented to cytolytic T lymphocytes by HLA-B40 requires the immunoproteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Processing of tumor-associated antigen by the proteasomes of dendritic cells controls in vivo T-cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A giant protease with potential to substitute for some functions of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Pathways accessory to proteasomal proteolysis are less efficient in major histocompatibility complex class I antigen production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Tripeptidyl peptidase II is the major peptidase needed to trim long antigenic precursors, but is not required for most MHC class I antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

No essential role for tripeptidyl peptidase II for the processing of LCMV-derived T cell epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Analysis of direct and cross-presentation of antigens in TPPII knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Tripeptidyl peptidase II is dispensable for the generation of both proteasome-dependent and proteasome-independent ligands of HLA-B27 and other class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Analysis of the role of tripeptidyl peptidase II in MHC class I antigen presentation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Need for tripeptidyl-peptidase II in major histocompatibility complex class I viral antigen processing when proteasomes are detrimental

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Processing of two latent membrane protein 1 MHC class I epitopes requires tripeptidyl peptidase II involvement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Inhibition of serine-peptidase activity enhances the generation of a survivin-derived HLA-A2-presented CTL epitope in colon-carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Two new proteases in the MHC class I processing pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Cytosolic aminopeptidases influence MHC class I-mediated antigen presentation in an allele-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The final N-terminal trimming of a subaminoterminal proline-containing HLA class I-restricted antigenic peptide in the cytosol is mediated by two peptidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Analysis of the fine specificity of rat, mouse and human TAP peptide transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Purification of a protease in red blood cells that degrades oxidatively damaged haemoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Insulin degradation: progress and potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Insulin-degrading enzyme exists inside of rat liver peroxisomes and degrades oxidized proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Immune recognition of a human renal cancer antigen through post-translational protein splicing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

An antigenic peptide produced by peptide splicing in the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

An antigen produced by splicing of noncontiguous peptides in the reverse order.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Splicing of distant peptide fragments occurs in the proteasome by transpeptidation and produces the spliced antigenic peptide derived from fibroblast growth factor-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Direct observation of ligand recognition by T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Introduction of soluble protein into the class I pathway of antigen processing and presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Tyrosinase degradation via two pathways during reverse translocation to the cytosol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Processing of a class I-restricted epitope from tyrosinase requires peptide N-glycanase and the cooperative action of endoplasmic reticulum aminopeptidase 1 and cytosolic proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

New functions for the matrix metalloproteinases in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Matrix metalloproteinases of normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Folding of matrix metalloproteinase-2 prevents endogenous generation of MHC class-I restricted epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A viral inhibitor of peptide transporters for antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Herpes simplex virus turns off the TAP to evade host immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The varicellovirus-encoded TAP inhibitor UL49.5 regulates the presentation of CTL epitopes by Qa-1b1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Features of TAP-independent MHC class I ligands revealed by quantitative mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Intramembrane proteolysis of signal peptides: an essential step in the generation of HLA-E epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

The quality control of MHC class I peptide loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line .220.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Optimization of the MHC class I peptide cargo is dependent on tapasin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Quantitative and qualitative influences of tapasin on the class I peptide repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

A proteolytic system that compensates for loss of proteasome function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0658-X

Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses

21 January 2018

1 reference

12 December 2020

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

12 December 2020

A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3.

1 reference

12 December 2020

Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study

1 reference

12 December 2020

Distribution of human leukocyte antigen-ABC and -D/DR antigens in the unfixed human testis

1 reference

12 December 2020

Structure of the gene of tum- transplantation antigen P35B: presence of a point mutation in the antigenic allele

1 reference

12 December 2020

Vitiligo in patients with melanoma: normal tissue antigens can be targets for cancer immunotherapy

1 reference

12 December 2020

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms

1 reference

12 December 2020

Extent of DNA methylation in human tumor cells

1 reference

12 December 2020

Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses.

1 reference

12 December 2020

Cytotoxic T cells recognize fragments of the influenza nucleoprotein

1 reference

12 December 2020

The intronic region of an incompletely spliced gp100 gene transcript encodes an epitope recognized by melanoma-reactive tumor-infiltrating lymphocytes

1 reference

12 December 2020

Transporter (TAP)- and proteasome-independent presentation of a melanoma-associated tyrosinase epitope

1 reference

12 December 2020

Characterization of the GAGE genes that are expressed in various human cancers and in normal testis

1 reference

12 December 2020

Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2'-deoxycytidine.

1 reference

12 December 2020

A human endogenous retroviral sequence encoding an antigen recognized on melanoma by cytolytic T lymphocytes.

1 reference

12 December 2020

The SSX-2 gene, which is involved in the t(X;18) translocation of synovial sarcomas, codes for the human tumor antigen HOM-MEL-40

1 reference

12 December 2020

A breast and melanoma-shared tumor antigen: T cell responses to antigenic peptides translated from different open reading frames

1 reference

12 December 2020

A new MAGE gene with ubiquitous expression does not code for known MAGE antigens recognized by T cells.

1 reference

12 December 2020

Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma

1 reference

12 December 2020

Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12Val) peptide vaccination of a patient, recognize 12Val-dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation

1 reference

12 December 2020

HLA antigens in ocular tissues. I. In vivo expression in human eyes

1 reference

12 December 2020

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression

1 reference

12 December 2020

A MAGE-A1 peptide presented to cytolytic T lymphocytes by both HLA-B35 and HLA-A1 molecules

1 reference

12 December 2020

Immunologically privileged sites

1 reference

12 December 2020

Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival

1 reference

12 December 2020

Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation

1 reference

12 December 2020

Identification on a human sarcoma of two new genes with tumor-specific expression

1 reference

12 December 2020

Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1

1 reference

12 December 2020

Translation initiation at non-AUG triplets in mammalian cells

1 reference

12 December 2020

A peptide derived from melanocytic protein gp100 and presented by HLA-B35 is recognized by autologous cytolytic T lymphocytes on melanoma cells

1 reference

12 December 2020

CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells

1 reference

12 December 2020

Identification of tumor-associated MHC class I ligands by a novel T cell-independent approach

1 reference

12 December 2020

A non-AUG-defined alternative open reading frame of the intestinal carboxyl esterase mRNA generates an epitope recognized by renal cell carcinoma-reactive tumor-infiltrating lymphocytes in situ

1 reference

12 December 2020

Identification of five MAGE-A1 epitopes recognized by cytolytic T lymphocytes obtained by in vitro stimulation with dendritic cells transduced with MAGE-A1.

1 reference

12 December 2020

An overview of the MAGE gene family with the identification of all human members of the family

1 reference

12 December 2020

HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences

1 reference

12 December 2020

Identification of a new MAGE gene with tumor-specific expression by representational difference analysis

1 reference

12 December 2020

A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation

1 reference

12 December 2020

Vitiligo in patients with metastatic melanoma: a good prognostic sign

1 reference

12 December 2020

A high molecular weight metalloendoprotease from the cytosol of mammalian cells.

1 reference

12 December 2020

Generation of survivin-specific CD8+ T effector cells by dendritic cells pulsed with protein or selected peptides

1 reference

12 December 2020

PRE2, highly homologous to the human major histocompatibility complex-linked RING10 gene, codes for a yeast proteasome subunit necessary for chrymotryptic activity and degradation of ubiquitinated proteins.

1 reference

12 December 2020

A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma

1 reference

12 December 2020

HLA class I-restricted lysis of leukemia cells by a CD8(+) cytotoxic T-lymphocyte clone specific for WT1 peptide

1 reference

12 December 2020

10.1007/S00018-011-0658-X

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21387143