(Q37868445)

24 August 2017

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title

The role of LKB1 in lung cancer (English)

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24 August 2017

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Montse Sanchez-Cespedes

series ordinal

1

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24 August 2017

1 September 2011

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24 August 2017

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24 August 2017

10

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24 August 2017

3

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24 August 2017

447-453

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https://scigraph.springernature.com/pub.10.1007/s10689-011-9443-0

24 August 2017

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Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene

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A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome

21 January 2018

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LKB1 modulates lung cancer differentiation and metastasis

21 January 2018

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Prevalence and specificity of LKB1 genetic alterations in lung cancers

21 January 2018

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Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity

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21 January 2018

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Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest

21 January 2018

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LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest

21 January 2018

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The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

21 January 2018

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21 January 2018

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21 January 2018

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MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm

21 January 2018

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The LKB1 tumor suppressor negatively regulates mTOR signaling

21 January 2018

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21 January 2018

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21 January 2018

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

21 January 2018

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par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

21 January 2018

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A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity

21 January 2018

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Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

21 January 2018

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The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity

21 January 2018

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Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.

21 January 2018

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21 January 2018

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21 January 2018

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The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation

21 January 2018

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Phosphatidylinositol ether lipid analogues induce AMP-activated protein kinase-dependent death in LKB1-mutant non small cell lung cancer cells

21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice

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12 December 2020

Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice

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12 December 2020

LKB1 protein expression in the evolution of glandular neoplasia of the lung.

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12 December 2020

Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells

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12 December 2020

BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines

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12 December 2020

Growth and molecular profile of lung cancer cells expressing ectopic LKB1: down-regulation of the phosphatidylinositol 3'-phosphate kinase/PTEN pathway.

1 reference

12 December 2020

Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types

1 reference

12 December 2020

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung

1 reference

12 December 2020

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

1 reference

12 December 2020

Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors

1 reference

12 December 2020

10.1007/S10689-011-9443-0

Identifiers

DOI

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24 August 2017

1 reference

PubMed ID

21516316