(Q24614112)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Norman Sharpless

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

D. Neil Hayes

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Kwok Kin Wong

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

3

Klarisa Rikova

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Takeshi Shimamura

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Autumn L Jackson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Matthew D Wilkerson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Christa L Borgman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Matthew S Buttarazzi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Benjamin A Sanofsky

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Kate L McNamara

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Kathleyn A Brandstetter

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Zandra E Walton

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Ting-Lei Gu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Jeffrey C Silva

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Katherine Crosby

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Geoffrey I Shapiro

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Sauveur-Michel Maira

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Hongbin Ji

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Diego H Castrillon

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Carla F Kim

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Carlos García-Echeverría

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

William Y Kim

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Jeffrey A Engelman

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Nabeel Bardeesy

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

language of work or name

English

0 references

publication date

1 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

547-559

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2901842/fullTextXML

inferred from PubMed Central ID database lookup

cites work

WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis

1 reference

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The basics of epithelial-mesenchymal transition

7 April 2017

1 reference

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Integrin-regulated FAK-Src signaling in normal and cancer cells

7 April 2017

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

7 April 2017

1 reference

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

7 April 2017

1 reference

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Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

The LKB1 tumor suppressor negatively regulates mTOR signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

7 April 2017

1 reference

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7 April 2017

1 reference

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Oncogenic pathway signatures in human cancers as a guide to targeted therapies

7 April 2017

1 reference

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FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes

7 April 2017

1 reference

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7 April 2017

A renaissance for SRC

1 reference

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LKB1 modulates lung cancer differentiation and metastasis

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice

26 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Adhesion signaling - crosstalk between integrins, Src and Rho.

27 September 2017

1 reference

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27 September 2017

1 reference

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Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

GEPAS, a web-based tool for microarray data analysis and interpretation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Mining gene expression profiles: expression signatures as cancer phenotypes

27 September 2017

1 reference

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Genetic determinants of cancer metastasis

27 September 2017

1 reference

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Cellular characterization of a novel focal adhesion kinase inhibitor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Prevalence and specificity of LKB1 genetic alterations in lung cancers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

LKB1-dependent signaling pathways

27 September 2017

1 reference

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Frequency and spectrum of cancers in the Peutz-Jeghers syndrome

27 September 2017

1 reference

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Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors

27 September 2017

1 reference

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Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells

27 September 2017

1 reference

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The interplay between Src and integrins in normal and tumor biology

27 September 2017

1 reference

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A module map showing conditional activity of expression modules in cancer

27 September 2017

1 reference

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Human bronchial epithelial cells neoplastically transformed by v-Ki-ras: altered response to inducers of terminal squamous differentiation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901842

The differential effects of mutant p53 alleles on advanced murine lung cancer

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20541700

12 December 2020

inferred from PubMed ID database lookup

Focal adhesion assembly

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20541700

12 December 2020

inferred from PubMed ID database lookup

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20541700

12 December 2020

inferred from PubMed ID database lookup

Forensic genetics and ethical, legal and social implications beyond the clinic

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.04.026

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.CCR.2010.04.026

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20541700%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

2 references