(Q37868990)

24 August 2017

1 reference

title

Specific PI3K isoform modulation in heart failure: lessons from transgenic mice (English)

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24 August 2017

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5

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24 August 2017

Alessandra Ghigo

1

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24 August 2017

Fulvio Morello

series ordinal

2

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24 August 2017

Alessia Perino

series ordinal

3

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24 August 2017

Federico Damilano

series ordinal

4

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24 August 2017

language of work or name

1 reference

1 September 2011

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Current heart failure reports

24 August 2017

published in

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24 August 2017

volume

8

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24 August 2017

issue

3

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24 August 2017

page(s)

168-175

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The phosphoinositide 3-kinase pathway

24 August 2017

cites work

1 reference

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Twice upon a time: PI3K's secret double life exposed

21 January 2018

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21 January 2018

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21 January 2018

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Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development

21 January 2018

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The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

21 January 2018

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Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

21 January 2018

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Intracellular signaling by Akt: bound to be specific

21 January 2018

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The multiple roles of PTEN in tumor suppression

21 January 2018

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The mouse SHIP2 (Inppl1) gene: complementary DNA, genomic structure, promoter analysis, and gene expression in the embryo and adult mouse

21 January 2018

1 reference

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Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction

21 January 2018

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Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

21 January 2018

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Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

21 January 2018

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The conserved phosphoinositide 3-kinase pathway determines heart size in mice

21 January 2018

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Temporally controlled overexpression of cardiac-specific PI3Kalpha induces enhanced myocardial contractility--a new transgenic model

21 January 2018

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Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

21 January 2018

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Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart

21 January 2018

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Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy

21 January 2018

1 reference

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PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA.

21 January 2018

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Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy

21 January 2018

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Role of phosphoinositide 3-kinase {alpha}, protein kinase C, and L-type Ca2+ channels in mediating the complex actions of angiotensin II on mouse cardiac contractility

21 January 2018

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

21 January 2018

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Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

21 January 2018

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Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

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Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function

21 January 2018

1 reference

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Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

21 January 2018

1 reference

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The role of endothelial PI3Kgamma activity in neutrophil trafficking

21 January 2018

1 reference

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Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma

21 January 2018

1 reference

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Deletion of the phosphoinositide 3-kinase p110gamma gene attenuates murine atherosclerosis

21 January 2018

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Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes

21 January 2018

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Hypertensive myocardial fibrosis and diastolic dysfunction: another model of inflammation?

21 January 2018

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Distinct effects of leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure

21 January 2018

1 reference

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Cardiac excitation-contraction coupling

21 January 2018

1 reference

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Role of cyclic nucleotide phosphodiesterase isoforms in cAMP compartmentation following beta2-adrenergic stimulation of ICa,L in frog ventricular myocytes

21 January 2018

1 reference

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Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

21 January 2018

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Cell signaling in space and time: where proteins come together and when they're apart

21 January 2018

1 reference

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PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

PI3Kgamma is required for PDE4, not PDE3, activity in subcellular microdomains containing the sarcoplasmic reticular calcium ATPase in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Cardiac sarcoplasmic reticulum calcium release and load are enhanced by subcellular cAMP elevations in PI3Kgamma-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Seven-transmembrane-spanning receptors and heart function

21 January 2018

1 reference

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beta-arrestins: traffic cops of cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Targeted inhibition of beta-adrenergic receptor kinase-1-associated phosphoinositide-3 kinase activity preserves beta-adrenergic receptor signaling and prolongs survival in heart failure induced by calsequestrin overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Dynamic regulation of phosphoinositide 3-kinase-gamma activity and beta-adrenergic receptor trafficking in end-stage human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Pharmacologic inhibition of phosphoinositide 3-kinase gamma (PI3Kγ) promotes infarct resorption and prevents adverse cardiac remodeling after myocardial infarction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Isoform-selective PI3K inhibitors as novel therapeutics for the treatment of acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Phosphatidylinositol 3-kinase gamma is a critical mediator of myocardial ischemic and adenosine-mediated preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Involvement of phosphoinositide 3-kinase gamma in angiogenesis and healing of experimental myocardial infarction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Insulin-Like Growth Factor-1 and PTEN Deletion Enhance Cardiac L-Type Ca 2+ Currents via Increased PI3Kα/PKB Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-011-0059-3

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

21 January 2018

1 reference

12 December 2020

Why does the myocardium fail? Insights from basic science

1 reference

12 December 2020

1 reference

12 December 2020

Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ.

1 reference

12 December 2020

The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway

1 reference

12 December 2020

Akt1 is required for physiological cardiac growth

1 reference

12 December 2020

Wortmannin, a phosphatidylinositol 3-kinase inhibitor, blocks antigen-mediated, but not CD3 monoclonal antibody-induced, activation of murine CD4+ T cells

1 reference

12 December 2020

Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy

1 reference

12 December 2020

10.1007/S11897-011-0059-3

Identifiers

DOI

1 reference

24 August 2017

1 reference