(Q37875475)

24 August 2017

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title

How integrins control mammary epithelial differentiation: a possible role for the ILK-PINCH-Parvin complex (English)

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24 August 2017

2

Charles H Streuli

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24 August 2017

Nicholas Rooney

1

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PubMed ID

21570968

24 August 2017

language of work or name

English

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publication date

10 May 2011

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24 August 2017

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24 August 2017

585

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24 August 2017

11

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24 August 2017

1663-1672

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Integrin signalling at a glance

24 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrins and cell-fate determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Functional atlas of the integrin adhesome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Signal co-operation between integrins and other receptor systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Mammalian Rho GTPases: new insights into their functions from in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Biomechanical regulation of cell orientation and fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Rac1 links integrin-mediated adhesion to the control of lactational differentiation in mammary epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Cell-matrix interactions in mammary gland development and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Cell-matrix interactions during development and apoptosis of the mouse mammary gland in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

The extracellular matrix as an adhesion checkpoint for mammary epithelial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Prolactin regulation of mammary gland development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Laminin mediates tissue-specific gene expression in mammary epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Dystroglycan controls signaling of multiple hormones through modulation of STAT5 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Stat5a is mandatory for adult mammary gland development and lactogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Essential functions of p21-activated kinase 1 in morphogenesis and differentiation of mammary glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

From cells to organs: building polarized tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrin-linked kinase is an adaptor with essential functions during mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

ILK, PINCH and parvin: the tIPP of integrin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

How ILK and kindlins cooperate to orchestrate integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrin-linked kinase is involved in matrix-induced hepatocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Expression of integrin-linked kinase is increased in differentiated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrin-linked kinase is required for TGF-β1 induction of dermal myofibroblast differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

The structural basis of integrin-linked kinase-PINCH interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Molecular dissection of PINCH-1 reveals a mechanism of coupling and uncoupling of cell shape modulation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

PINCH, N(i)ck and the ILK: network wiring at cell-matrix adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Identification and kinetic analysis of the interaction between Nck-2 and DOCK180

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrin-linked kinase interactions with ELMO2 modulate cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

The Ras suppressor Rsu-1 binds to the LIM 5 domain of the adaptor protein PINCH1 and participates in adhesion-related functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

The roles of two distinct regions of PINCH-1 in the regulation of cell attachment and spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Consequences of loss of PINCH2 expression in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

AlphaPIX and betaPIX and their role in focal adhesion formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Akt is required for Stat5 activation and mammary differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Functional molecular imaging of ILK-mediated Akt/PKB signaling cascades and the associated role of beta-parvin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

CdGAP associates with actopaxin to regulate integrin-dependent changes in cell morphology and motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

21 January 2018

Paxillin comes of age

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

Regulation of cell-matrix adhesion dynamics and Rac-1 by integrin linked kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.05.014

10.1016/J.FEBSLET.2011.05.014

21 January 2018

Identifiers

DOI

1 reference

release_fu3xe7lco5hcleb2lc7tetmmxm

24 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fu3xe7lco5hcleb2lc7tetmmxm

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24 November 2022

based on heuristic

PubMed ID

21570968

1 reference

PubMed ID

21570968