(Q37883249)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

review article

1 reference

title

Genome-wide association studies (GWAS): impact on elucidating the aetiology of diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

genome-wide association study

2 February 2020

main subject

0 references

author

Struan F.A. Grant

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1

Hakon Hakonarson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

publication date

1 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

Diabetes - Metabolism: Research and Reviews

2 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

685-696

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

Conference on "Multidisciplinary approaches to nutritional problems". Symposium on "Diabetes and health". Nutrition interventions for the prevention of type 2 diabetes

2 February 2020

cites work

1 reference

Global and societal implications of the diabetes epidemic

21 January 2018

1 reference

Worldwide increase in incidence of Type I diabetes--the analysis of the data on published incidence trends

21 January 2018

1 reference

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

21 January 2018

1 reference

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

21 January 2018

1 reference

A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study

21 January 2018

1 reference

A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

21 January 2018

1 reference

A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3

21 January 2018

1 reference

Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes

21 January 2018

1 reference

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

21 January 2018

1 reference

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

21 January 2018

1 reference

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

21 January 2018

1 reference

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

21 January 2018

1 reference

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

21 January 2018

1 reference

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

21 January 2018

1 reference

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

21 January 2018

1 reference

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

21 January 2018

1 reference

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

21 January 2018

1 reference

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

21 January 2018

1 reference

Insights on pathogenesis of type 2 diabetes from MODY genetics

21 January 2018

1 reference

Prediction and interaction in complex disease genetics: experience in type 1 diabetes

21 January 2018

1 reference

Mapping genes in diabetes. Genetic epidemiological perspective

21 January 2018

1 reference

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

21 January 2018

1 reference

A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins.

21 January 2018

1 reference

HL-A antigens and diabetes mellitus.

21 January 2018

1 reference

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

21 January 2018

1 reference

Remapping the insulin gene/IDDM2 locus in type 1 diabetes

21 January 2018

1 reference

CTLA-4 in autoimmune diseases--a general susceptibility gene to autoimmunity?

21 January 2018

1 reference

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

1 reference

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

21 January 2018

1 reference

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

21 January 2018

1 reference

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

21 January 2018

1 reference

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

21 January 2018

1 reference

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

21 January 2018

1 reference

The International HapMap Project

21 January 2018

1 reference

A haplotype map of the human genome

21 January 2018

1 reference

Whole-genome genotyping with the single-base extension assay

21 January 2018

1 reference

A genome-wide scalable SNP genotyping assay using microarray technology

21 January 2018

1 reference

A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility

21 January 2018

1 reference

Common genetic variants on 5p14.1 associate with autism spectrum disorders

21 January 2018

1 reference

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

21 January 2018

1 reference

Variants of DENND1B associated with asthma in children

21 January 2018

1 reference

Complement factor H polymorphism in age-related macular degeneration

21 January 2018

1 reference

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

21 January 2018

1 reference

Shared and distinct genetic variants in type 1 diabetes and celiac disease

21 January 2018

1 reference

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

21 January 2018

1 reference

Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms

21 January 2018

1 reference

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

21 January 2018

1 reference

Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1.

21 January 2018

1 reference

Protein kinase C theta (PKCtheta): a key player in T cell life and death

21 January 2018

1 reference

In silico replication of the genome-wide association results of the Type 1 Diabetes Genetics Consortium.

21 January 2018

1 reference

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

21 January 2018

1 reference

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

21 January 2018

1 reference

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

21 January 2018

1 reference

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

21 January 2018

1 reference

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

21 January 2018

1 reference

Variants in MTNR1B influence fasting glucose levels

21 January 2018

1 reference

TCF7L2: the biggest story in diabetes genetics since HLA?

21 January 2018

1 reference

Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2.

21 January 2018

1 reference

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

21 January 2018

1 reference

Parental origin of sequence variants associated with complex diseases

21 January 2018

1 reference

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

21 January 2018

1 reference

Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

1 reference

Finding the missing heritability of complex diseases

21 January 2018

1 reference

Rare variants create synthetic genome-wide associations

21 January 2018

1 reference

Interpretation of association signals and identification of causal variants from genome-wide association studies

21 January 2018

1 reference

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

1 reference

Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP.

21 January 2018

1 reference

Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants

21 January 2018

1 reference

Variation in FTO contributes to childhood obesity and severe adult obesity

21 January 2018

1 reference

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

21 January 2018

1 reference

Common variants near MC4R are associated with fat mass, weight and risk of obesity

21 January 2018

1 reference

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

21 January 2018

1 reference

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

21 January 2018

1 reference

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups

21 January 2018

1 reference

The fetal insulin hypothesis: an alternative explanation of the association of low birthweight with diabetes and vascular disease

21 January 2018

1 reference

Activating mutations in the gene encoding Kir6.2 alter fetal and postnatal growth and also cause neonatal diabetes.

21 January 2018

1 reference

Insulin gene mutations as a cause of permanent neonatal diabetes

21 January 2018

1 reference

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes

21 January 2018

1 reference

Type 2 diabetes risk alleles are associated with reduced size at birth

21 January 2018

1 reference

Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene.

21 January 2018

1 reference

Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.

21 January 2018

1 reference

Examination of all type 2 diabetes GWAS loci reveals HHEX-IDE as a locus influencing pediatric BMI.

21 January 2018

1 reference

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

Risk alleles for multiple sclerosis identified by a genomewide study

21 January 2018

1 reference

Role of PTPN22 in type 1 diabetes and other autoimmune diseases

21 January 2018

1 reference

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

21 January 2018

1 reference

A common variant of HMGA2 is associated with adult and childhood height in the general population

21 January 2018

1 reference

Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells

21 January 2018

1 reference

Assignment of the TCF-4 gene (TCF7L2) to human chromosome band 10q25.3

21 January 2018

1 reference

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

21 January 2018

1 reference

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.

21 January 2018

1 reference

The accelerator hypothesis: weight gain as the missing link between Type I and Type II diabetes

21 January 2018

1 reference

The TCF7L2 locus and type 1 diabetes

21 January 2018

1 reference

Analysis of the type 2 diabetes gene, TCF7L2, in 13,795 type 1 diabetes cases and control subjects

21 January 2018

1 reference

Association analysis of type 2 diabetes Loci in type 1 diabetes.

21 January 2018

1 reference

No association of multiple type 2 diabetes loci with type 1 diabetes

21 January 2018

1 reference

Analysis of the type 2 diabetes-associated single nucleotide polymorphisms in the genes IRS1, KCNJ11, and PPARG2 in type 1 diabetes

21 January 2018

1 reference

Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.

21 January 2018

1 reference

21 January 2018

1 reference

Transcription factor 7-like 2-gene polymorphism is related to fasting C peptide in latent autoimmune diabetes in adults (LADA).

21 January 2018

1 reference

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

21 January 2018

1 reference

A HapMap harvest of insights into the genetics of common disease

21 January 2018

1 reference

Genetic mapping in human disease

21 January 2018

1 reference

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

21 January 2018

1 reference

Inactivation of the Fto gene protects from obesity

21 January 2018

1 reference

A map of open chromatin in human pancreatic islets

21 January 2018

1 reference

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

21 January 2018

1 reference

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region

21 January 2018

1 reference

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

21 January 2018

1 reference

A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

1 reference

An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures

21 January 2018

1 reference

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

1 reference

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

21 January 2018

1 reference

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

21 January 2018

1 reference

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

21 January 2018

1 reference

Association of the cytotoxic T lymphocyte-associated antigen 4 gene with type 1 diabetes: evidence for independent effects of two polymorphisms on the same haplotype block

21 January 2018

1 reference

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

21 January 2018

2 references

21 January 2018

7 January 2021

A genetic link between type 2 diabetes and prostate cancer

1 reference

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

21 January 2018

1 reference

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

21 January 2018

1 reference

7 January 2021

Toward further mapping of the association between the IL2RA locus and type 1 diabetes

1 reference

7 January 2021

Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles

1 reference

7 January 2021

Identifiers

DOI

10.1002/DMRR.1221

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21630414%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference