(Q37887551)

English

Model organisms reveal insight into human neurodegenerative disease: ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS.

scientific article published on 10 June 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

7 references

25 April 2019

20 June 2019

30 June 2019

14 September 2019

20 November 2019

11 December 2019

19 December 2019

Model organisms reveal insight into human neurodegenerative disease: ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS. (English)

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

0 references

amyotrophic lateral sclerosis

7 references

25 April 2019

20 June 2019

30 June 2019

14 September 2019

20 November 2019

11 December 2019

19 December 2019

neurodegeneration

4 references

25 April 2019

20 June 2019

30 June 2019

14 September 2019

genetic variation

1 reference

14 September 2019

1 reference

20 November 2019

DNA-binding protein

1 reference

11 December 2019

nerve tissue protein

1 reference

19 December 2019

1 reference

based on heuristic

inferred from title

Nancy M. Bonini

1

object named as

Nancy M Bonini

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

author name string

Aaron D Gitler

2

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

publication date

10 June 2011

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

1 November 2011

7 references

25 April 2019

20 June 2019

30 June 2019

14 September 2019

20 November 2019

11 December 2019

19 December 2019

Journal of Molecular Neuroscience

8 references

Europe PubMed Central

PMC publication ID

24 August 2017

25 April 2019

20 June 2019

30 June 2019

14 September 2019

20 November 2019

11 December 2019

19 December 2019

45

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

676-683

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Epidemiology of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Non-ATG-initiated translation directed by microsatellite expansions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

TDP-43-mediated neuron loss in vivo requires RNA-binding activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Genetic animal models of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Roles of trinucleotide-repeat RNA in neurological disease and degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

TAR DNA-binding protein 43 in neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

A Drosophila model for TDP-43 proteinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Rethinking ALS: the FUS about TDP-43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

RNA toxicity is a component of ataxin-3 degeneration in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Spinocerebellar ataxia 2 (SCA2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Lysosomes: fusion and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Exploring genetic interactions and networks with yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Drosophila in the study of neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Drosophila as a model for human neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Drosophila, the golden bug, emerges as a tool for human genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Men are but worms: neuronal cell death in C elegans and vertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Cyclin dependent kinases and cell cycle control (nobel lecture).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

A Drosophila model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

The genome sequence of Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

6 September 2017

Prion-like disorders: blurring the divide between transmissibility and infectivity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

14 September 2017

Spinocerebellar ataxia type 2 with parkinsonism in ethnic Chinese

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

23 June 2018

The role of the SCA2 trinucleotide repeat expansion in 89 autosomal dominant cerebellar ataxia families. Frequency, clinical and genetic correlates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

23 June 2018

Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

1 September 2018

Prevalence of spinocerebellar ataxia type 2 mutation among Italian Parkinsonian patients

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1 September 2018

The parkinsonian phenotype of spinocerebellar ataxia type 2.

1 reference

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1 September 2018

Complex phenotypes in an Indian family with homozygous SCA2 mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

1 September 2018

SCA-2 presenting as parkinsonism in an Alberta family: clinical, genetic, and PET findings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207127

1 September 2018

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

1 reference

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1 September 2018

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

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1 September 2018

The expansion of the CAG repeat in ataxin-2 is a frequent cause of autosomal dominant spinocerebellar ataxia

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21 January 2018

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https://pubmed.ncbi.nlm.nih.gov/21660502

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rare association of motor neuron disease and spinocerebellar ataxia type 2 (SCA2): a new case and review of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/21660502

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinocerebellar ataxia type 2 presenting as familial levodopa-responsive parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21660502

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinocerebellar ataxia type 2 with Levodopa-responsive parkinsonism culminating in motor neuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21660502

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12031-011-9548-9

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

24 August 2017

ResearchGate publication ID

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