(Q37893575)

24 August 2017

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title

Possible role for Ca2+ in the pathophysiology of the prion protein? (English)

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24 August 2017

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Caterina Peggion

1

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24 August 2017

Alessandro Bertoli

series ordinal

2

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24 August 2017

M Catia Sorgato

series ordinal

3

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24 August 2017

publication date

1 May 2011

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24 August 2017

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24 August 2017

volume

37

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24 August 2017

issue

3

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24 August 2017

page(s)

241-249

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Prions: protein aggregation and infectious diseases

24 August 2017

cites work

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Novel proteinaceous infectious particles cause scrapie

21 January 2018

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Three-dimensional structures of prion proteins

21 January 2018

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21 January 2018

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

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129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

21 January 2018

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Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration

21 January 2018

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Mice devoid of PrP are resistant to scrapie

21 January 2018

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Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons

21 January 2018

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Motor behavioral and neuropathological deficits in mice deficient for normal prion protein expression

21 January 2018

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Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal

21 January 2018

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Cellular prion protein promotes regeneration of adult muscle tissue.

21 January 2018

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The prion's elusive reason for being

21 January 2018

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Physiology of the prion protein

21 January 2018

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Is, indeed, the prion protein a Harlequin servant of "many" masters?

21 January 2018

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Calcium and neurodegeneration

21 January 2018

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Scrapie prions alter receptor-mediated calcium responses in cultured cells

21 January 2018

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Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release

21 January 2018

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Neurotoxicity of a prion protein fragment

21 January 2018

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Prion protein fragment 106-126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line

21 January 2018

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Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106-126.

21 January 2018

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Scrapie-infected GT1-1 cells show impaired function of voltage-gated N-type calcium channels (Ca(v) 2.2) which is ameliorated by quinacrine treatment

21 January 2018

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Scrapie infection alters the membrane and synaptic properties of mouse hippocampal CA1 pyramidal neurones.

21 January 2018

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Alterations in potassium currents may trigger neurodegeneration in murine scrapie

21 January 2018

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Synaptic plasticity in the CA1 area of the hippocampus of scrapie-infected mice

21 January 2018

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Intrinsic physiological and morphological properties of principal cells of the hippocampus and neocortex in hamsters infected with scrapie

21 January 2018

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Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease

21 January 2018

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An integrated, temporal study of the behavioural, electrophysiological and neuropathological consequences of murine prion disease.

21 January 2018

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Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice

21 January 2018

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Heterogeneous amyloid-formed ion channels as a common cytotoxic mechanism: implications for therapeutic strategies against amyloidosis

21 January 2018

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21 January 2018

Amyloid peptide channels

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Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

21 January 2018

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Channel formation by a neurotoxic prion protein fragment

21 January 2018

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Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line

21 January 2018

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Prion peptide fragment PrP[106-126] forms distinct cation channel types.

21 January 2018

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Channels formed with a mutant prion protein PrP(82-146) homologous to a 7-kDa fragment in diseased brain of GSS patients

21 January 2018

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Ionic mechanisms of action of prion protein fragment PrP(106-126) in rat basal forebrain neurons

21 January 2018

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Prion: the chameleon protein

21 January 2018

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21 January 2018

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Increased expression of CaM kinase II alpha in the brains of scrapie-infected mice

21 January 2018

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Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

21 January 2018

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Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

21 January 2018

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An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.

21 January 2018

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The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway.

21 January 2018

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Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress

21 January 2018

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Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival

21 January 2018

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Prion protein is necessary for normal synaptic function

21 January 2018

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Rescue of neurophysiological phenotype seen in PrP null mice by transgene encoding human prion protein

21 January 2018

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Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus

21 January 2018

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The prion protein knockout mouse: a phenotype under challenge

21 January 2018

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Age-dependent loss of PTP and LTP in the hippocampus of PrP-null mice

21 January 2018

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Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control

21 January 2018

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Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents.

21 January 2018

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Pathogenic human prion protein rescues PrP null phenotype in transgenic mice.

21 January 2018

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Loss of the cellular prion protein affects the Ca2+ homeostasis in hippocampal CA1 neurons.

21 January 2018

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Alterations in Ca2+-buffering in prion-null mice: association with reduced afterhyperpolarizations in CA1 hippocampal neurons.

21 January 2018

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Calcium-activated potassium currents in mammalian neurons.

21 January 2018

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Prion protein affects Ca2+-activated K+ currents in cerebellar purkinje cells

21 January 2018

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Role of prions in neuroprotection and neurodegeneration: a mechanism involving glutamate receptors?

21 January 2018

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Enhanced susceptibility of Prnp-deficient mice to kainate-induced seizures, neuronal apoptosis, and death: Role of AMPA/kainate receptors

21 January 2018

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Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1.

21 January 2018

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Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury

21 January 2018

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Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

21 January 2018

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Ca(2+) signalling in mitochondria: mechanism and role in physiology and pathology.

21 January 2018

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Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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The prion protein and its paralogue Doppel affect calcium signaling in Chinese hamster ovary cells.

21 January 2018

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Cellular prion protein is implicated in the regulation of local Ca2+ movements in cerebellar granule neurons.

21 January 2018

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Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain.

21 January 2018

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Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

21 January 2018

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Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways.

21 January 2018

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Role of alpha7 nicotinic acetylcholine receptor in calcium signaling induced by prion protein interaction with stress-inducible protein 1.

21 January 2018

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Physiological role of the cellular prion protein (PrPc): protein profiling study in two cell culture systems

21 January 2018

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Cellular prion protein overexpression disturbs cellular homeostasis in SH-SY5Y neuroblastoma cells but does not alter p53 expression: a proteomic study.

21 January 2018

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Differential expression of calcium-related genes in gastric cancer cells transfected with cellular prion protein.

21 January 2018

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A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

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Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.

21 January 2018

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A beta oligomers - a decade of discovery

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

21 January 2018

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

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Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

21 January 2018

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Calcium hypothesis of Alzheimer's disease

21 January 2018

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Prion protein codon 129 polymorphism and risk of Alzheimer disease.

21 January 2018

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

21 January 2018

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Memory impairment in transgenic Alzheimer mice requires cellular prion protein

21 January 2018

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Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

21 January 2018

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Prion protein and Abeta-related synaptic toxicity impairment

21 January 2018

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The prion protein as a receptor for amyloid-beta.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIOF.161

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24 August 2017

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