(Q27313215)

English

Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival

scientific article (publication date: 2010)

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scholarly article

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Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival (English)

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prion protein family

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neurodegeneration

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based on heuristic

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author name string

Abhisek Mukherjee

1

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Diego Morales-Scheihing

2

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Dennisse Gonzalez-Romero

3

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Kristi Green

4

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Giulio Taglialatela

5

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Claudio Soto

6

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language of work or name

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publication date

2010

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6

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10

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e1001138

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copyright license

Creative Commons Attribution 4.0 International

7 October 2010

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April 2022 Public Data File from Crossref

copyright status

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Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Evaluation of quinacrine treatment for prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

The allograft inflammatory factor-1 in Creutzfeldt-Jakob disease brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Prion diseases of humans and animals: their causes and molecular basis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

NeuN, a neuronal specific nuclear protein in vertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

21 March 2017

Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Prions: protein aggregation and infectious diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Degenerating synaptic boutons in prion disease: microglia activation without synaptic stripping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Recent advances in prion chemotherapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

TTC, fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Cell-free propagation of prion strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

The stress rheostat: an interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

A systematic review of prion therapeutics in experimental models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Unsuccessful intraventricular pentosan polysulphate treatment of variant Creutzfeldt-Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

The role of the endoplasmic reticulum in the accumulation of beta-amyloid peptide in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Stressing out the ER: a role of the unfolded protein response in prion-related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Sourcing a chemical succession for cyclosporin from parasites and human pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

In vitro generation of infectious scrapie prions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Approaches to therapy of prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Misfolded proteins, endoplasmic reticulum stress and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Prion diseases--close to effective therapy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Diagnosing prion diseases: needs, challenges and hopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Calcineurin: a central controller of signalling in eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Calcineurin in memory and bidirectional plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Calcineurin regulation of neuronal plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Tacrolimus: a further update of its use in the management of organ transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Atypical inflammation in the central nervous system in prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Rapamycin in transplantation: a review of the evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Use of thapsigargin to study Ca2+ homeostasis in cardiac cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Amphotericin B delays both scrapie agent replication and PrP-res accumulation early in infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Experimental scrapie in the mouse: a review of an important model disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

28 September 2017

Transport of prion protein across the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

Calcineurin in human brain and its relation to extrapyramidal system. Immunohistochemical study on postmortem human brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

Chemoprophylaxis of scrapie in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

Sulphate polyanions prolong the incubation period of scrapie-infected hamsters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951383

31 May 2018

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

vCJD tissue distribution and transmission by transfusion--a worst-case scenario coming true?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Early behavioural changes in scrapie-affected mice and the influence of dapsone

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Vacuolation in murine prion disease: an informative artifact.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Results of quinacrine administration to patients with Creutzfeldt-Jakob disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

MS-8209, an amphotericin B analogue, delays the appearance of spongiosis, astrogliosis and PrPres accumulation in the brain of scrapie-infected hamsters

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Less protease-resistant PrP in a patient with sporadic CJD treated with intraventricular pentosan polysulphate.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Continuous intraventricular infusion of pentosan polysulfate: clinical trial against prion diseases.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001138

21 January 2018

Failure to ameliorate Creutzfeldt-Jakob disease with amphotericin B therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949081

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraventricular pentosan polysulphate in human prion diseases: an observational study in the UK

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949081

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluoro-Jade: novel fluorochromes for detecting toxicant-induced neuronal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949081

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PPAT.1001138

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