(Q37434914)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Hafiz Mohmmad Abdul

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Michelle A Sama

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jennifer L Furman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Diana M Mathis

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Tina L Beckett

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Adam M Weidner

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Ela S Patel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Irfan Baig

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

M Paul Murphy

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Harry LeVine

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Christopher M Norris

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

1 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

12957-12969

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point

9 February 2020

cites work

1 reference

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Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

23 August 2017

1 reference

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Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity.

23 August 2017

1 reference

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Ascomycin and FK506: pharmacology and therapeutic potential as anticonvulsants and neuroprotectants

23 August 2017

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Selective inhibitors of nuclear factor of activated T cells: potential therapeutic drugs for the treatment of immunological and inflammatory diseases

23 August 2017

1 reference

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Hippocampal 'zipper' slice studies reveal a necessary role for calcineurin in the increased activity of L-type Ca(2+) channels with aging

23 August 2017

1 reference

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Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS

23 August 2017

1 reference

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NFAT signaling in neural development and axon growth

23 August 2017

1 reference

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Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity

23 August 2017

1 reference

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Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: function-based and target-based discovery approaches

23 August 2017

1 reference

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Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice

23 August 2017

1 reference

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Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

23 August 2017

1 reference

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Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure

23 August 2017

1 reference

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Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

23 August 2017

1 reference

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Regulation of cardiac hypertrophy by intracellular signalling pathways

23 August 2017

1 reference

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Electrophysiological mechanisms of delayed excitotoxicity: positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release

23 August 2017

1 reference

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Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo

23 August 2017

1 reference

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Potential inflammatory biomarkers in Alzheimer's disease

23 August 2017

1 reference

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Rationale for T cell inhibition by cyclosporin A in major autoimmune diseases

23 August 2017

1 reference

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Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

23 August 2017

1 reference

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Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models

23 August 2017

1 reference

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Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

23 August 2017

1 reference

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Glia and their cytokines in progression of neurodegeneration

23 August 2017

1 reference

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Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses

23 August 2017

1 reference

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GSK-3 kinases enhance calcineurin signaling by phosphorylation of RCNs

23 August 2017

1 reference

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Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Calcineurin regulation of neuronal plasticity

23 August 2017

1 reference

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Transcriptional regulation by calcium, calcineurin, and NFAT

23 August 2017

1 reference

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Selective inhibition of Abeta42 production by NSAID R-enantiomers

23 August 2017

1 reference

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NFAT signaling: choreographing the social lives of cells

23 August 2017

1 reference

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Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture

23 August 2017

1 reference

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NFAT: ubiquitous regulator of cell differentiation and adaptation

23 August 2017

1 reference

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Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease

23 August 2017

1 reference

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Calcineurin links Ca2+ dysregulation with brain aging

23 August 2017

1 reference

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Selective changes of calcineurin (protein phosphatase 2B) activity in Alzheimer's disease cerebral cortex

23 August 2017

1 reference

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Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis

23 August 2017

1 reference

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Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signalin

23 August 2017

1 reference

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Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

23 August 2017

1 reference

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Mild cognitive impairment: clinical characterization and outcome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells

23 August 2017

1 reference

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Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

23 August 2017

1 reference

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Phosphoprotein phosphatase activities in Alzheimer disease brain

23 August 2017

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Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

23 August 2017

1 reference

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

23 August 2017

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The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

23 August 2017

1 reference

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Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals

23 August 2017

1 reference

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Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes.

6 September 2017

1 reference

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Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.

14 September 2017

1 reference

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Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress.

14 September 2017

1 reference

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DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice

14 September 2017

1 reference

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Ibuprofen decreases cytokine-induced amyloid beta production in neuronal cells.

14 September 2017

1 reference

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Alternative splicing and expression of human and mouse NFAT genes.

28 September 2017

1 reference

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Alzheimer's beta-peptide oligomer formation at physiologic concentrations

26 June 2018

1 reference

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L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

26 June 2018

1 reference

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Calcium channel density and hippocampal cell death with age in long-term culture.

26 June 2018

1 reference

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Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal.

26 June 2018

1 reference

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The inhibitory effects of beta-amyloid on glutamate and glucose uptakes by cultured astrocytes.

26 June 2018

1 reference

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Reduction of calcineurin enzymatic activity in Alzheimer's disease: correlation with neuropathologic changes.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Sequence-specific interactions of nuclear factors with the insulin gene enhancer.

26 June 2018

1 reference

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Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks

26 June 2018

1 reference

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Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain.

2 September 2018

1 reference

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Overactivation of calcineurin induced by amyloid-beta and prion proteins

2 September 2018

1 reference

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Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Expression of calcipressin1, an inhibitor of the phosphatase calcineurin, is altered with aging and Alzheimer's disease.

2 September 2018

1 reference

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Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain

2 September 2018

1 reference

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

2 September 2018

1 reference

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A new cell-permeable peptide allows successful allogeneic islet transplantation in mice

2 September 2018

1 reference

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Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

2 September 2018

1 reference

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Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Adult mouse astrocytes degrade amyloid-beta in vitro and in situ

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Protein phosphatase 1 is a molecular constraint on learning and memory.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

Isoform-specific redistribution of calcineurin A alpha and A beta in the hippocampal CA1 region of gerbils after transient ischemia.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

beta-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: implications for Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782445

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

2 September 2018

1 reference

12 December 2020

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

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12 December 2020

GFAP promoter elements required for region-specific and astrocyte-specific expression

1 reference

12 December 2020

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

1 reference

12 December 2020

Amyloid beta peptide (25-35) inhibits Na+-dependent glutamate uptake in rat hippocampal astrocyte cultures

1 reference

12 December 2020

Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease

1 reference

12 December 2020

10.1523/JNEUROSCI.1064-09.2009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

release_hkzgmfd5dzhojjar5k675er7aq

9 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hkzgmfd5dzhojjar5k675er7aq

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828810%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference