(Q37896087)

25 August 2017

1 reference

title

Osteopontin: a potentially important therapeutic target in cancer (English)

1 reference

25 August 2017

Santosh Kumar

9

0 references

Dhiraj Kumar

object named as

Dhiraj Kumar

15

0 references

Gopal Kundu

20

object named as

Gopal C Kundu

1 reference

25 August 2017

3

Goutam Chakraborty

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21718227

5 December 2024

author name string

Mansoor Ahmed

1

1 reference

25 August 2017

Reeti Behera

2

1 reference

25 August 2017

Shalini Jain

4

1 reference

25 August 2017

Vinit Kumar

5

1 reference

25 August 2017

Priyanka Sharma

6

1 reference

25 August 2017

Anuradha Bulbule

7

1 reference

25 August 2017

Smita Kale

8

1 reference

25 August 2017

Rosalin Mishra

10

1 reference

25 August 2017

Remya Raja

11

1 reference

25 August 2017

Supriya Saraswati

12

1 reference

25 August 2017

Rajinder Kaur

13

1 reference

25 August 2017

Gowrishankar Soundararajan

14

1 reference

25 August 2017

Dhanashri Thorat

16

1 reference

25 August 2017

Megha Sanyal

17

1 reference

25 August 2017

Anuja Ramdasi

18

1 reference

25 August 2017

Pompom Ghosh

19

1 reference

25 August 2017

Gopal C. Kundu

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21718227

5 December 2024

language of work or name

English

0 references

publication date

25 July 2011

1 reference

full work available at URL

25 August 2017

http://www.informapharmascience.com/doi/abs/10.1517/14728222.2011.594438

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21718227

http://www.tandfonline.com/doi/pdf/10.1517/14728222.2011.594438

5 December 2024

1 reference

https://api.crossref.org/works/10.1517/14728222.2011.594438

Expert Opinion on Therapeutic Targets

5 December 2024

published in

1 reference

25 August 2017

volume

15

1 reference

25 August 2017

issue

9

1 reference

25 August 2017

page(s)

1113-1126

1 reference

25 August 2017

cites work

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

P700: the primary electron donor of photosystem I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Role of osteopontin in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin: role in cell signaling and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin-deficiency suppresses growth of B16 melanoma cells implanted in bone and osteoclastogenesis in co-cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin: regulation in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Elevated tumor and serum levels of the hypoxia-associated protein osteopontin are associated with prognosis for soft tissue sarcoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Prognostic significance of osteopontin expression in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin regulates multiple functions contributing to human colon cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Prognostic significance of osteopontin expression in early-stage non-small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin is a marker for cancer aggressiveness and patient survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

The multifaceted roles of osteopontin in cell signaling, tumor progression and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin expression correlates with angiogenesis and survival in malignant astrocytoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

The role of Osteopontin in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Identification of promoter regions involved in cell- and developmental stage-specific osteopontin expression in bone, kidney, placenta, and mammary gland: an analysis of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin is required for full expression of the transformed phenotype by the ras oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Increased cell death in osteopontin-deficient cardiac fibroblasts occurs by a caspase-3-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Differential expression of intracellular and secreted osteopontin isoforms by murine macrophages in response to toll-like receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin: role in immune regulation and stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Polymeric osteopontin employs integrin alpha9beta1 as a receptor and attracts neutrophils by presenting a de novo binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin is produced by mast cells and affects IgE-mediated degranulation and migration of mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin facilitates bone resorption, decreasing bone mineral crystallinity and content during calcium deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Transformed mammalian cells secrete specific proteins and phosphoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta through the NF-kappaB and MAPK pathways in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin increases CD44 expression and cell adhesion in RAW 264.7 murine leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Control of osteopontin signaling and function by post-translational phosphorylation and protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

An osteopontin splice variant induces anchorage independence in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin-c is a selective marker of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin induces beta-catenin signaling through activation of Akt in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin induces AP-1-mediated secretion of urokinase-type plasminogen activator through c-Src-dependent epidermal growth factor receptor transactivation in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Nuclear factor-inducing kinase plays a crucial role in osteopontin-induced MAPK/IkappaBalpha kinase-dependent nuclear factor kappaB-mediated promatrix metalloproteinase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Identification of osteopontin-dependent signaling pathways in a mouse model of human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

p38 kinase is crucial for osteopontin-induced furin expression that supports cervical cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Systemic endocrine instigation of indolent tumor growth requires osteopontin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Senescent stromal-derived osteopontin promotes preneoplastic cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Cutting edge: IL-1beta mediates the proangiogenic activity of osteopontin-activated human monocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Inhibition of osteopontin suppresses in vitro and in vivo angiogenesis in endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Lung cancer osteopontin isoforms exhibit angiogenic functional heterogeneity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin-c splicing isoform contributes to ovarian cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Primary breast carcinoma: association of mammographic calcifications with osteopontin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Clinicopathologic significance of the basal-like subtype of breast cancer: a comparison with hormone receptor and Her2/neu-overexpressing phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Small integrin-binding proteins as serum markers for prostate cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin: an emerging therapeutic target for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

A humanized anti-osteopontin antibody protects from Concanavalin A induced-liver injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

A novel RGD antagonist that targets both alphavbeta3 and alpha5beta1 induces apoptosis of angiogenic endothelial cells on type I collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

A small molecule antagonist of the alpha(v)beta3 integrin suppresses MDA-MB-435 skeletal metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Targeted gene silencing using RGD-labeled chitosan nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Anti-CD44 induces apoptosis in T lymphoma via mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Agelastatin A: a novel inhibitor of osteopontin-mediated adhesion, invasion, and colony formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin expression is required for myofibroblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Bcr-Abl regulates osteopontin transcription via Ras, PI-3K, aPKC, Raf-1, and MEK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Inhibition of osteopontin expression and function in oral cancer cell lines by antisense oligonucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Transformation-specific secreted phosphoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Expression of osteopontin, a target gene of de-regulated Wnt signaling, predicts survival in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.594438

Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype

21 January 2018

22

1 reference

https://api.crossref.org/works/10.1517/14728222.2011.594438

The temporal expression of osteopontin (SPP-1) in the rodent model of alcoholic steatohepatitis: a potential biomarker

5 December 2024

29

1 reference

https://api.crossref.org/works/10.1517/14728222.2011.594438

Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells

5 December 2024

48

1 reference

https://api.crossref.org/works/10.1517/14728222.2011.594438

Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells

5 December 2024

56

1 reference

https://api.crossref.org/works/10.1517/14728222.2011.594438

Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis

5 December 2024

95

1 reference

https://api.crossref.org/works/10.1517/14728222.2011.594438

5 December 2024

Identifiers

1 reference

25 August 2017

1 reference