(Q37900388)

25 August 2017

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title

Focal adhesion kinase -- the basis of local hypertrophic signaling domains (English)

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25 August 2017

K G Franchini

1

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25 August 2017

publication date

2 July 2011

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Journal of Molecular and Cellular Cardiology

25 August 2017

published in

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25 August 2017

volume

52

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25 August 2017

issue

2

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25 August 2017

page(s)

485-492

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Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

25 August 2017

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Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment

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Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth

7 January 2021

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Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice

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A role for focal adhesion kinase in phenylephrine-induced hypertrophy of rat ventricular cardiomyocytes

7 January 2021

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Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy

7 January 2021

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Endothelin-induced cardiac myocyte hypertrophy: role for focal adhesion kinase

7 January 2021

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Early activation of p160ROCK by pressure overload in rat heart

7 January 2021

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Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy

7 January 2021

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Targeting Focal Adhesion Kinase With Small Interfering RNA Prevents and Reverses Load-Induced Cardiac Hypertrophy in Mice

7 January 2021

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Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes

7 January 2021

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Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

7 January 2021

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Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.

7 January 2021

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Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.

7 January 2021

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7 January 2021

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Crystal structure of the FERM domain of focal adhesion kinase.

7 January 2021

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Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography

7 January 2021

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The structural basis of localization and signaling by the focal adhesion targeting domain

7 January 2021

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Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

7 January 2021

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

7 January 2021

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7 January 2021

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7 January 2021

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FERM domain interaction promotes FAK signaling

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

7 January 2021

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The signaling and biological implications of FAK overexpression in cancer

7 January 2021

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Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex

7 January 2021

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Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation

7 January 2021

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Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53

7 January 2021

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An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

FAK phosphorylation sites mapped by mass spectrometry

7 January 2021

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Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

A role for focal adhesion kinase in cardiac mitochondrial biogenesis induced by mechanical stress.

7 January 2021

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Targeting to C-terminal myosin heavy chain may explain mechanotransduction involving focal adhesion kinase in cardiac myocytes

7 January 2021

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Stimulus interval, rate and direction differentially regulate phosphorylation for mechanotransduction in neonatal cardiac myocytes

7 January 2021

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Nuclear compartmentalization of FAK and FRNK in cardiac myocytes

7 January 2021

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Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Integrin activation and focal complex formation in cardiac hypertrophy.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cells

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

inferred from DOI database lookup

7 January 2021

based on heuristic

Costameres are sites of force transmission to the substratum in adult rat cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Costameres, focal adhesions, and cardiomyocyte mechanotransduction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Focal adhesion kinase as a regulator of cell tension in the progression of cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

RhoA/ROCK signaling is critical to FAK activation by cyclic stretch in cardiac myocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Activation of focal adhesion kinase by protein kinase C epsilon in neonatal rat ventricular myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Load-induced focal adhesion kinase activation in the myocardium: role of stretch and contractile activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Focal adhesion kinase is involved in mechanosensing during fibroblast migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Focal adhesion kinase mediates MEF2 and c-Jun activation by stretch: role in the activation of the cardiac hypertrophic genetic program

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Mechanical stress-induced sarcomere assembly for cardiac muscle growth in length and width

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Cardiac regulation by phosphoinositide 3-kinases and PTEN

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

ARHGAP21 associates with FAK and PKCzeta and is redistributed after cardiac pressure overload

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Striated muscle-specific beta(1D)-integrin and FAK are involved in cardiac myocyte hypertrophic response pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Association of focal adhesion kinase with tuberous sclerosis complex 2 in the regulation of s6 kinase activation and cell growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

GFP-FRNK disrupts focal adhesions and induces anoikis in neonatal rat ventricular myocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Integrin and FAK-mediated MAPK activation is required for cyclic strain mitogenic effects in Caco-2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Focal adhesion kinase is a load-dependent governor of the slow contractile and oxidative muscle phenotype.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

PYK2 expression and phosphorylation increases in pressure overload-induced left ventricular hypertrophy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Increased expression and phosphorylation of focal adhesion kinase correlates with dysfunction in the volume-overloaded human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Differentiation of C2C12 myoblasts is critically regulated by FAK signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

Quantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2011.06.021

10.1016/J.YJMCC.2011.06.021

7 January 2021

Identifiers

DOI

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25 August 2017

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