(Q37910045)

25 August 2017

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title

The roles of thrombin and protease-activated receptors in inflammation (English)

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25 August 2017

0 references

2

1 reference

25 August 2017

Liang Ma

1

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25 August 2017

publication date

2 August 2011

1 reference

Seminars in Immunopathology

25 August 2017

published in

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25 August 2017

volume

34

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25 August 2017

issue

1

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25 August 2017

page(s)

63-72

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Inflammation-coagulation network: are serine protease receptors the knot?

25 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Thrombin signalling and protease-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Protease-activated receptors: contribution to physiology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Protease-activated receptors in hemostasis, thrombosis and vascular biology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Proteinase-activated receptor-2 in human skin: tissue distribution and activation of keratinocytes by mast cell tryptase

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

21 January 2018

12 December 2020

Interactions of mast cell tryptase with thrombin receptors and PAR-2.

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Inhibition of factor Xa suppresses the expression of tissue factor in human monocytes and lipopolysaccharide-induced endotoxemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Thrombin increases inflammatory cytokine and angiogenic growth factor secretion in human adipose cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Thrombin induces macrophage migration inhibitory factor release and upregulation in urothelium: a possible contribution to bladder inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Thrombin and Phenotypic Modulation of the Endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Hug tightly and say goodbye: role of endothelial ICAM-1 in leukocyte transmigration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Human cytomegalovirus increases HUVEC sensitivity to thrombin and modulates expression of thrombin receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Thrombin promotes proinflammatory phenotype in human vascular smooth muscle cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Thrombin induces the expression of oncostatin M via AP-1 activation in human macrophages: a link between coagulation and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Concentration dependent dual effect of thrombin in endothelial cells via Par-1 and Pi3 Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Efficacy and safety of recombinant human activated protein C for severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Inflammation and the activated protein C anticoagulant pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Regulation of blood coagulation by the protein C anticoagulant pathway: novel insights into structure-function relationships and molecular recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

The cytoprotective protein C pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1-dependent leukocyte recruitment in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Protease-activated receptor-1 regulates cytokine production and induces the suppressor of cytokine signaling-3 in microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Proteinase-activated receptors-1 and 2 induce electrogenic Cl- secretion in the mouse cecum by distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Proteinase-activated receptors induce interleukin-8 expression by intestinal epithelial cells through ERK/RSK90 activation and histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Deficiency of PAR4 attenuates cerebral ischemia/reperfusion injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Proteinase-activated receptor-4 (PAR4) activation leads to sensitization of rat joint primary afferents via a bradykinin B2 receptor-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Luminal cathepsin g and protease-activated receptor 4: a duet involved in alterations of the colonic epithelial barrier in ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Complement protease MASP-1 activates human endothelial cells: PAR4 activation is a link between complement and endothelial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Protease-activated receptor 2 blocking peptide counteracts endotoxin-induced inflammation and coagulation and ameliorates renal fibrin deposition in a rat model of acute renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Alpha A-crystallin and alpha B-crystallin, newly identified interaction proteins of protease-activated receptor-2, rescue astrocytes from C2-ceramide- and staurosporine-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Transactivation of Sphingosine 1-Phosphate Receptors Is Essential for Vascular Barrier Regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Release of gelatinase A during platelet activation mediates aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-011-0281-9

Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo

21 January 2018

1 reference

12 December 2020

Protease-Activated Receptor-1 Down-regulates the Murine Inflammatory and Humoral Response to Helicobacter pylori

1 reference

12 December 2020

Proteinase-activated receptors.

1 reference

12 December 2020

Platelet release of trimolecular complex components MT1-MMP/TIMP2/MMP2: involvement in MMP2 activation and platelet aggregation.

1 reference

12 December 2020

Role of the coagulation system in allergic inflammation in the upper airways

1 reference

12 December 2020

Outside-in signals delivered by matrix metalloproteinase-1 regulate platelet function

1 reference

12 December 2020

Protease-activated receptors in vascular biology

1 reference

12 December 2020

Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1.

1 reference

12 December 2020

Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106).

1 reference

12 December 2020

Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand.

1 reference

12 December 2020

Special lecture: glial reactivity after damage: implications for scar formation and neuronal recovery.

1 reference

12 December 2020

Prevention of endotoxin-induced mortality by antitissue factor immunization

1 reference

12 December 2020

Focal ischemia induces expression of protease-activated receptor1 (PAR1) and PAR3 on microglia and enhances PAR4 labeling in the penumbra

1 reference

12 December 2020

Thrombin and protease-activated receptors (PARs) in atherothrombosis.

1 reference

12 December 2020

Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity.

1 reference

12 December 2020

Thrombin as a common downstream target blocking both platelet and monocyte activation.

1 reference

12 December 2020

10.1007/S00281-011-0281-9

Identifiers

DOI

1 reference

25 August 2017

1 reference