(Q37913502)

English

Glucagon gene expression in the endocrine pancreas: the role of the transcription factor Pax6 in α-cell differentiation, glucagon biosynthesis and secretion

scientific article published on October 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 August 2017

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Europe PubMed Central

Glucagon gene expression in the endocrine pancreas: the role of the transcription factor Pax6 in α-cell differentiation, glucagon biosynthesis and secretion (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

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1 reference

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cell differentiation

1 reference

based on heuristic

inferred from title

author name string

Y Gosmain

1

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

C Cheyssac

2

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

M Heddad Masson

3

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

C Dibner

4

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

J Philippe

5

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

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based on heuristic

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publication date

1 October 2011

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Europe PubMed Central

PubMed publication ID

25 August 2017

Diabetes, Obesity and Metabolism

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Europe PubMed Central

PubMed publication ID

25 August 2017

13 Suppl 1

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Europe PubMed Central

PubMed publication ID

25 August 2017

31-38

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

Structure and pancreatic expression of the insulin and glucagon genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Mechanisms underlying proglucagon gene expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G1 control element

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Foxa2 is required for the differentiation of pancreatic alpha-cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Differential regulation of the glucagon and insulin I gene promoters by the basic helix-loop-helix transcription factors E47 and BETA2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Essential interaction of Egr-1 at an islet-specific response element for basal and gastrin-dependent glucagon gene transactivation in pancreatic alpha-cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Opposing actions of Arx and Pax4 in endocrine pancreas development

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

MafB is required for islet beta cell maturation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

The pancreatic beta-cell-specific transcription factor Pax-4 inhibits glucagon gene expression through Pax-6.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

The beta-cell specific transcription factor Nkx6.1 inhibits glucagon gene transcription by interfering with Pax6.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Pancreatic organogenesis--developmental mechanisms and implications for therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Not for the eyes only: PAX6 and glucose metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

A case of novel de novo paired box gene 6 (PAX6) mutation with early-onset diabetes mellitus and aniridia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Relative roles of the different Pax6 domains for pancreatic alpha cell development

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Pax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Pax6 regulates the proglucagon processing enzyme PC2 and its chaperone 7B2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

7B2 is a specific intracellular binding protein of the prohormone convertase PC2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Glucolipotoxicity: fuel excess and beta-cell dysfunction.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

The essential role of glucagon in the pathogenesis of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Alpha cell function in health and disease: influence of glucagon-like peptide-1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Transcription factors of beta-cell differentiation and maturation in isolated human islets: Effects of high glucose, high free fatty acids and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01445.X

21 January 2018

Identifiers

10.1111/J.1463-1326.2011.01445.X

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

ResearchGate publication ID

0 references

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