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English
Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue.
scientific article published on 12 August 2011
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scholarly article
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Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
review article
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Europe PubMed Central
title
Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
main subject
macrophage
0 references
inflammation
0 references
preproinsulin
1 reference
based on heuristic
inferred from title
insulin resistance
1 reference
based on heuristic
inferred from title
author
Clare Reynolds
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
Fiona C McGillicuddy
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3
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Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
Helen M Roche
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
21835098
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retrieved
10 February 2020
author name string
Karen A Harford
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
publication date
12 August 2011
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
published in
Proceedings of the Nutrition Society
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
volume
70
1 reference
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Europe PubMed Central
PubMed publication ID
21835098
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
issue
4
1 reference
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Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
page(s)
408-417
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
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10 February 2020
cites work
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
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7 January 2021
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Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
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A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
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7 January 2021
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Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
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7 January 2021
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Development of monocytes, macrophages, and dendritic cells
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7 January 2021
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Obesity induces a phenotypic switch in adipose tissue macrophage polarization
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7 January 2021
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Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
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7 January 2021
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Regulatory T cells and immune tolerance
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7 January 2021
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TLR signaling
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Liposomal methylprednisolone differentially regulates the expression of TNF and IL-10 in human alveolar macrophages
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7 January 2021
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Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.
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Diet induction of monocyte chemoattractant protein-1 and its impact on obesity.
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7 January 2021
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Obesity is associated with macrophage accumulation in adipose tissue
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7 January 2021
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Type 2 diabetes as an inflammatory disease
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7 January 2021
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Biochemical and functional characterization of three activated macrophage populations.
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7 January 2021
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Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity
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Cutting edge: biasing immune responses by directing antigen to macrophage Fc gamma receptors.
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7 January 2021
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Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.
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7 January 2021
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CCR2 modulates inflammatory and metabolic effects of high-fat feeding
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7 January 2021
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Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance
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Crossref
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7 January 2021
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CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
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7 January 2021
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Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle
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7 January 2021
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Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
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7 January 2021
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inferred from DOI database lookup
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage infiltration into adipose tissue: initiation, propagation and remodeling.
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Global and societal implications of the diabetes epidemic
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fat uses a TOLL-road to connect inflammation and diabetes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage polarization comes of age.
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-induced inflammatory cytokine secretion in human adipose tissue stromovascular cells
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
The chemokine system in diverse forms of macrophage activation and polarization
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Class II MHC peptide loading by the professionals
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
APC-derived cytokines and T cell polarization in autoimmune inflammation
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Natural regulatory T cells control the development of atherosclerosis in mice
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
TLR4 links innate immunity and fatty acid-induced insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Troglitazone Antagonizes Tumor Necrosis Factor-α-induced Reprogramming of Adipocyte Gene Expression by Inhibiting the Transcriptional Regulatory Functions of NF-κB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
IKK-beta links inflammation to obesity-induced insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
How dying cells alert the immune system to danger
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
The immune response in atherosclerosis: a double-edged sword
1 reference
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Crossref
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7 January 2021
based on heuristic
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Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue.
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
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Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice
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7 January 2021
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Foxp3 in control of the regulatory T cell lineage
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Normalization of obesity-associated insulin resistance through immunotherapy
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7 January 2021
based on heuristic
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Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
1 reference
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
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inferred from DOI database lookup
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of PPAR gamma in immune cells impairs the ability of abscisic acid to improve insulin sensitivity by suppressing monocyte chemoattractant protein-1 expression and macrophage infiltration into white adipose tissue
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
PPAR gamma is highly expressed in F4/80(hi) adipose tissue macrophages and dampens adipose-tissue inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
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Inflammation and insulin resistance
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inflammation and metabolic disorders
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adipocyte biology.
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
A central role for JNK in obesity and insulin resistance
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metchnikoff's Legacy in 2008.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665111000565
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1017/S0029665111000565
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
PubMed publication ID
21835098
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21835098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21835098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
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