(Q37918451)

25 August 2017

1 reference

title

Transforming growth factor-β signaling in tumor initiation, progression and therapy in breast cancer: an update (English)

1 reference

25 August 2017

1 reference

Xuyu Zu

1

1 reference

25 August 2017

Qinghai Zhang

2

1 reference

25 August 2017

Renxian Cao

3

1 reference

25 August 2017

Jianghua Liu

4

1 reference

25 August 2017

Jing Zhong

5

1 reference

25 August 2017

Gebo Wen

6

1 reference

25 August 2017

Deliang Cao

7

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25 August 2017

publication date

16 August 2011

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25 August 2017

published in

Cell and Tissue Research

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25 August 2017

volume

347

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25 August 2017

issue

1

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25 August 2017

page(s)

73-84

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Myeloid-derived suppressor cells in mammary tumor progression in FVB Neu transgenic mice.

25 August 2017

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Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors

21 January 2018

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TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

21 January 2018

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Signal transduction by the TGF-beta superfamily

21 January 2018

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Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

21 January 2018

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RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells.

21 January 2018

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Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer

21 January 2018

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Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer

21 January 2018

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Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-beta kinase antagonist, in mice

21 January 2018

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TGF-beta and BMP7 interactions in tumour progression and bone metastasis

21 January 2018

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Differential intracellular signalling induced by TGF-beta in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis.

21 January 2018

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Transforming growth factor-beta signaling-deficient fibroblasts enhance hepatocyte growth factor signaling in mammary carcinoma cells to promote scattering and invasion

21 January 2018

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Knockdown of the transforming growth factor-beta type III receptor impairs motility and invasion of metastatic cancer cells

21 January 2018

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Evidence for a biphasic apoptotic pathway induced by melatonin in MCF-7 breast cancer cells.

21 January 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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Mammary tumor heterogeneity in the expansion of myeloid-derived suppressor cells.

21 January 2018

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Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.

21 January 2018

1 reference

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Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

21 January 2018

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Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics

21 January 2018

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Transforming growth factor-beta signaling at the tumor-bone interface promotes mammary tumor growth and osteoclast activation.

21 January 2018

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Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.

21 January 2018

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SFRP1 reduction results in an increased sensitivity to TGF-β signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Smad4-independent TGF-beta signaling in tumor cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor-beta signaling and ubiquitinators in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Loss of expression of transforming growth factor beta type II receptor correlates with high tumour grade in human breast in-situ and invasive carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transgenic Mice Expressing a Dominant-Negative Mutant Type II Transforming Growth Factor-β Receptor Exhibit Impaired Mammary Development and Enhanced Mammary Tumor Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Circulating transforming growth factor-beta-1 and breast cancer prognosis: results from the Shanghai Breast Cancer Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Epithelial-mesenchymal transition and tumour invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

CdGAP is required for transforming growth factor β- and Neu/ErbB-2-induced breast cancer cell motility and invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor-beta co-receptor endoglin suppresses breast cancer invasion and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Autocrine TGF-β protects breast cancer cells from apoptosis through reduction of BH3-only protein, Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Systemic delivery of an oncolytic adenovirus expressing soluble transforming growth factor-β receptor II-Fc fusion protein can inhibit breast cancer bone metastasis in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

TGFbeta signalling: a complex web in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Switching TGFβ from a tumor suppressor to a tumor promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Breast cancer stem cells: a new challenge for breast cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor-beta in cancer and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Autocrine PDGFR signaling promotes mammary cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Antiestrogens induce transforming growth factor beta-mediated immunosuppression in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

TGF-beta signaling, tumor microenvironment and tumor progression: the butterfly effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Tgf-Beta pathway as a therapeutic target in bone metastases.

21 January 2018

1 reference

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The basics of epithelial-mesenchymal transition

21 January 2018

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Transforming growth factor-beta: a target for cancer therapy

21 January 2018

1 reference

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17-Beta-estradiol inhibits transforming growth factor-beta signaling and function in breast cancer cells via activation of extracellular signal-regulated kinase through the G protein-coupled receptor 30.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Downregulation of transforming growth factor β (TGFβ) and latent TGFβ binding protein (LTBP)-4 expression in late stage canine mammary tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

The type III TGF-beta receptor suppresses breast cancer progression through GIPC-mediated inhibition of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transcriptome profiling of a TGF-beta-induced epithelial-to-mesenchymal transition reveals extracellular clusterin as a target for therapeutic antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

BRCA1 interacts with Smad3 and regulates Smad3-mediated TGF-beta signaling during oxidative stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transcriptional control by the TGF-beta/Smad signaling system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-beta-mediated cancer cell invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

The dynamic roles of TGF-β in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Epithelial-mesenchymal transition in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Homeoprotein Six1 Increases TGF-β Type I Receptor and Converts TGF-β Signaling from Suppressive to Supportive for Tumor Growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Bone sialoprotein mediates the tumor cell-targeted prometastatic activity of transforming growth factor beta in a mouse model of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Targeting transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Mammary tumor suppression by transforming growth factor beta 1 transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

TGF-beta signaling: a tale of two responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Dual effects of TGF-beta on ERalpha-mediated estrogenic transcriptional activity in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Multigene targeting of signal transduction pathways for the treatment of breast and prostate tumors: comparison between combination therapies employing bispecific oligonucleotides with either Rapamycin or Paclitaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Minimal effects on immune parameters following chronic anti-TGF-beta monoclonal antibody administration to normal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Tetraspanin CD151 regulates transforming growth factor beta signaling: implication in tumor metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Molecular definition of breast tumor heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Estrogen receptor alpha attenuates transforming growth factor-beta signaling in breast cancer cells independent from agonistic and antagonistic ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

A delicate balance: TGF-beta and the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Preclinical efficacy of cystatin C to target the oncogenic activity of transforming growth factor Beta in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Mechanisms of the epithelial-mesenchymal transition by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Cathepsin G-mediated activation of pro-matrix metalloproteinase 9 at the tumor-bone interface promotes transforming growth factor-beta signaling and bone destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Regulation of Smad activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Down-regulation of FXYD3 is induced by transforming growth factor-β signaling via ZEB1/δEF1 in human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

ATF3, an adaptive-response gene, enhances TGFβ signaling and cancer-initiating cell features in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Cellular and molecular basis for the regulation of inflammation by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

Context-Dependent Bidirectional Regulation of the MutS Homolog 2 by Transforming Growth Factor β Contributes to Chemoresistance in Breast Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

TGF-beta signaling in neuronal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1225-3

10.1007/S00441-011-1225-3

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference