(Q37924914)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

1 reference

title

Microvascular dysfunction: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

main subject

pathogenesis

0 references

arterial hypertension

0 references

0 references

1 reference

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Etto C Eringa

series ordinal

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

7

Yvo M Smulders

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

9

Erik H Serné

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

4

Amy M Jonk

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

Coenraad Dirk Adriaan Stehouwer

12 February 2020

series ordinal

6

object named as

Coen D Stehouwer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1

Michiel P De Boer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

3

Nienke J Wijnstok

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Alphons J Houben

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

1 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

5-18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883642%20AND%20SRC:MED&resulttype=core&format=json

Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells

12 February 2020

cites work

1 reference

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Protein kinase C theta activation induces insulin-mediated constriction of muscle resistance arteries

21 January 2018

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The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action

21 January 2018

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Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT.

21 January 2018

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Angiotensin II increases glucose utilization during acute hyperinsulinemia via a hemodynamic mechanism

21 January 2018

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Enhanced vascular activity of endogenous endothelin-1 in obese hypertensive patients.

21 January 2018

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Insulin stimulates both endothelin and nitric oxide activity in the human forearm.

21 January 2018

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Angiotensin II type 1 and type 2 receptors regulate basal skeletal muscle microvascular volume and glucose use.

21 January 2018

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Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding

21 January 2018

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Impaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle

21 January 2018

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Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo

21 January 2018

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Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle

21 January 2018

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Birth weight relates to salt sensitivity of blood pressure in healthy adults

21 January 2018

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Sunitinib-induced reduction in skin microvascular density is a reversible phenomenon

21 January 2018

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Physiological hyperinsulinaemia increases intramuscular microvascular reactive hyperaemia and vasomotion in healthy volunteers

21 January 2018

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Free fatty acid levels modulate microvascular function: relevance for obesity-associated insulin resistance, hypertension, and microangiopathy

21 January 2018

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Impaired microvascular function in obesity: implications for obesity-associated microangiopathy, hypertension, and insulin resistance

21 January 2018

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Impaired local microvascular vasodilatory effects of insulin and reduced skin microvascular vasomotion in obese women

21 January 2018

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Microvascular function: a potential link between salt sensitivity, insulin resistance and hypertension

21 January 2018

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Reduced access to insulin-sensitive tissues in dogs with obesity secondary to increased fat intake

21 January 2018

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Physiological hyperinsulinemia in dogs augments access of macromolecules to insulin-sensitive tissues

21 January 2018

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Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of skeletal muscle resistance arteries in the presence of tumor necrosis factor-alpha dependence on c-Jun N-terminal kinase

21 January 2018

1 reference

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Hypertension-independent microvascular rarefaction in the obese Zucker rat model of the metabolic syndrome

21 January 2018

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NaCl sensitivity of essential hypertensive patients is related to insulin resistance.

21 January 2018

1 reference

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Angiotensin II-induced effects on adipose and skeletal muscle tissue blood flow and lipolysis in normal-weight and obese subjects

21 January 2018

1 reference

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Local inflammation and hypoxia abolish the protective anticontractile properties of perivascular fat in obese patients.

21 January 2018

1 reference

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Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition

21 January 2018

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Decreased muscle capillary permeability surface area in type 2 diabetic subjects

21 January 2018

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A central role for JNK in obesity and insulin resistance

21 January 2018

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Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

21 January 2018

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Individuals at increased coronary heart disease risk are characterized by an impaired microvascular function in skin

21 January 2018

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TNF-alpha levels are associated with skin capillary recruitment in humans: a potential explanation for the relationship between TNF-alpha and insulin resistance

21 January 2018

1 reference

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Retinal vessel diameters and risk of hypertension: the Rotterdam Study

21 January 2018

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A model of physical factors in the structural adaptation of microvascular networks in normotension and hypertension.

21 January 2018

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A tissue in the tissue: models of microvascular plasticity

21 January 2018

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Angiotensin mediates forearm glucose uptake by hemodynamic rather than direct effects.

21 January 2018

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Why blockade of the renin-angiotensin system reduces the incidence of new-onset diabetes

21 January 2018

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Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

21 January 2018

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Subtle acquired renal injury as a mechanism of salt-sensitive hypertension

21 January 2018

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Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension

21 January 2018

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Acute angiotensin II receptor blockade improves insulin-induced microvascular function in hypertensive individuals

21 January 2018

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Angiotensin II enhances insulin-stimulated whole-body glucose disposal but impairs insulin-induced capillary recruitment in healthy volunteers

21 January 2018

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21 January 2018

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Obesity blunts microvascular recruitment in human forearm muscle after a mixed meal

21 January 2018

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Obese but not normal-weight women with polycystic ovary syndrome are characterized by metabolic and microvascular insulin resistance

21 January 2018

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Impaired microvascular function in normal children: effects of adiposity and poor glucose handling

21 January 2018

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Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance.

21 January 2018

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Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms.

21 January 2018

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Effects of infliximab treatment on insulin resistance in patients with rheumatoid arthritis and ankylosing spondylitis

21 January 2018

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Oscillations in the human cutaneous blood perfusion signal modified by endothelium-dependent and endothelium-independent vasodilators

21 January 2018

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Preserved relative dispersion but blunted stimulation of mean flow, absolute dispersion, and blood volume by insulin in skeletal muscle of patients with essential hypertension.

21 January 2018

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Getting the message across: mechanisms of physiological cross talk by adipose tissue

21 January 2018

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Impaired tissue perfusion: a pathology common to hypertension, obesity, and diabetes mellitus

21 January 2018

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Tumor necrosis factor-alpha induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway

21 January 2018

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Vascular insulin resistance in prehypertensive rats: role of PI3-kinase/Akt/eNOS signaling

21 January 2018

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Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man.

21 January 2018

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Infusing lipid raises plasma free fatty acids and induces insulin resistance in muscle microvasculature

21 January 2018

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The renin-angiotensin system and insulin resistance

21 January 2018

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Hyperinsulinemia fails to augment ET-1 action in the skeletal muscle vascular bed in vivo in humans

21 January 2018

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Endothelin contributes to basal vascular tone and endothelial dysfunction in human obesity and type 2 diabetes.

21 January 2018

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Human epicardial adipose tissue is a source of inflammatory mediators

21 January 2018

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Effect of valsartan on the incidence of diabetes and cardiovascular events

21 January 2018

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Perivascular adipose tissue and its role in type 2 diabetes and cardiovascular disease

21 January 2018

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Cardiovascular actions of insulin

21 January 2018

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Effects of Intrabrachial metacholine infusion on muscle capillary recruitment and forearm glucose uptake during physiological hyperinsulinemia in obese, insulin-resistant individuals

21 January 2018

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Decreased microvascular vasomotion and myogenic response in rat skeletal muscle in association with acute insulin resistance

21 January 2018

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Retinal arteriolar narrowing predicts incidence of diabetes: the Australian Diabetes, Obesity and Lifestyle (AusDiab) Study

21 January 2018

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Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure

21 January 2018

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Renin-angiotensin system and angiotensin receptor blockers in the metabolic syndrome

21 January 2018

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Skin blood flowmotion response to insulin iontophoresis in normal subjects

21 January 2018

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Renin-angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and hypertension: an integrated view in humans.

21 January 2018

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Coronary circulatory function abnormalities in insulin resistance: insights from positron emission tomography

21 January 2018

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Insulin sensitivity: modulation by nutrients and inflammation

21 January 2018

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Microvascular dysfunction: a potential pathophysiological role in the metabolic syndrome

21 January 2018

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Impaired skin capillary recruitment in essential hypertension is caused by both functional and structural capillary rarefaction.

21 January 2018

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Capillary recruitment is impaired in essential hypertension and relates to insulin's metabolic and vascular actions

21 January 2018

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Direct evidence for insulin-induced capillary recruitment in skin of healthy subjects during physiological hyperinsulinemia

21 January 2018

1 reference

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Microvascular function relates to insulin sensitivity and blood pressure in normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1549-8719.2011.00130.X

Insulin sensitivity is preserved despite disrupted endothelial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1549-8719.2011.00130.X

Inflammation and insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1549-8719.2011.00130.X

Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy

21 January 2018

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Delayed transcapillary transport of insulin to muscle interstitial fluid in obese subjects

21 January 2018

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Wavelet analysis of oscillations in the peripheral blood circulation measured by laser Doppler technique

21 January 2018

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Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

21 January 2018

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Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure

21 January 2018

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Microvascular function is impaired in ankylosing spondylitis and improves after tumour necrosis factor alpha blockade

21 January 2018

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Cross-talk between the insulin and angiotensin signaling systems

21 January 2018

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Mixed meal and light exercise each recruit muscle capillaries in healthy humans

21 January 2018

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Active role for the vasculature in the delivery of insulin to skeletal muscle

21 January 2018

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Insulin-mediated hemodynamic changes are impaired in muscle of Zucker obese rats

21 January 2018

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Caveolin-1 is required for vascular endothelial insulin uptake

21 January 2018

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Coronary risk factors and myocardial perfusion in asymptomatic adults: the Multi-Ethnic Study of Atherosclerosis (MESA).

21 January 2018

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Physiological hyperinsulinemia has no detectable effect on access of macromolecules to insulin-sensitive tissues in healthy humans

21 January 2018

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Microcirculation and the metabolic syndrome

21 January 2018

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Associations between the metabolic syndrome and retinal microvascular signs: the Atherosclerosis Risk In Communities study.

21 January 2018

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Retinal arteriolar diameter and risk for hypertension.

21 January 2018

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Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons

21 January 2018

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Insulin-induced vasodilatation: physiology or pharmacology?

21 January 2018

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"Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease.

21 January 2018

1 reference

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