(Q37944146)

25 August 2017

title

The role of innate immune-stimulated epithelial apoptosis during gastrointestinal inflammatory diseases (English)

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25 August 2017

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Richard H Siggers

1

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25 August 2017

David J Hackam

series ordinal

2

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25 August 2017

publication date

11 October 2011

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Cellular and Molecular Life Sciences

25 August 2017

published in

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25 August 2017

volume

68

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25 August 2017

issue

22

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25 August 2017

page(s)

3623-3634

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Regulation of apoptosis during homeostasis and disease in the intestinal epithelium

25 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4.

21 January 2018

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Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrow-derived cells and parenchymal cells.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation

21 January 2018

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In vivo CpG DNA/toll-like receptor 9 interaction induces regulatory properties in CD4+CD62L+ T cells which prevent intestinal inflammation in the SCID transfer model of colitis

21 January 2018

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CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms.

21 January 2018

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Immune effects and mechanisms of action of CpG motifs

21 January 2018

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21 January 2018

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Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

21 January 2018

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21 January 2018

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Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

21 January 2018

1 reference

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Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut.

21 January 2018

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Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Secretory Mediators Regulate Nod2-Induced Tolerance in Human Macrophages

21 January 2018

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NOD2 mutations and anti-Saccharomyces cerevisiae antibodies are risk factors for Crohn's disease in African Americans

21 January 2018

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Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells

21 January 2018

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Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

21 January 2018

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21 January 2018

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Disordered enterocyte signaling and intestinal barrier dysfunction in the pathogenesis of necrotizing enterocolitis

21 January 2018

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Neurodevelopmental outcomes of very low-birth-weight infants with necrotizing enterocolitis: a systematic review of observational studies

21 January 2018

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21 January 2018

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Cell death in the colonic epithelium during inflammatory bowel diseases: CD95/Fas and beyond.

21 January 2018

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Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

21 January 2018

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Triptolide ameliorates IL-10-deficient mice colitis by mechanisms involving suppression of IL-6/STAT3 signaling pathway and down-regulation of IL-17.

21 January 2018

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Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility

21 January 2018

1 reference

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Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors

21 January 2018

1 reference

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A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort

21 January 2018

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Linkage of inflammatory bowel disease to human chromosome 6p

21 January 2018

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Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci

21 January 2018

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21 January 2018

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Resistance to EGF-R (erbB-1) and VEGF-R modulating agents

21 January 2018

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Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation.

21 January 2018

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Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis.

21 January 2018

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5-aminosalicylic acid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease

21 January 2018

1 reference

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The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases

21 January 2018

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Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer

21 January 2018

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ERK activation drives intestinal tumorigenesis in Apc(min/+) mice

21 January 2018

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Salmonella-mediated gene therapy in experimental colitis in mice

21 January 2018

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21 January 2018

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Bacterial Colonization Affects the Intestinal Proteome of Preterm Pigs Susceptible to Necrotizing Enterocolitis

21 January 2018

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RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRs

21 January 2018

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Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

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Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

21 January 2018

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Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis

21 January 2018

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12 December 2020

Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis

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12 December 2020

Increased expression of RelA/nuclear factor-kappa B protein correlates with colorectal tumorigenesis

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12 December 2020

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.

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12 December 2020

The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

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12 December 2020

Increased apoptosis accompanies neoplastic development in the human colorectum.

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12 December 2020

Activation of cytokine-producing and antitumor activities of natural killer cells and macrophages by engagement of Toll-like and NOD-like receptors

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12 December 2020

Proteins and an inflammatory network expressed in colon tumors

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12 December 2020

Gene therapy for cancer: bacteria-mediated anti-angiogenesis therapy.

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12 December 2020

Mutations of p53 and K-ras correlate TF expression in human colorectal carcinomas: TF downregulation as a marker of poor prognosis

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12 December 2020

Crohn's disease: NOD2, autophagy and ER stress converge

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12 December 2020

Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis

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12 December 2020

DAMPening inflammation by modulating TLR signalling

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12 December 2020

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

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12 December 2020

New therapies and preventive approaches for necrotizing enterocolitis: report of a research planning workshop

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12 December 2020

Interleukin-19 protects mice from innate-mediated colonic inflammation

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12 December 2020

The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation

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12 December 2020

Intestinal epithelial apoptosis initiates gross bowel necrosis in an experimental rat model of neonatal necrotizing enterocolitis

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12 December 2020

Colorectal carcinogenesis in germ-free and conventionally reared rats: different intestinal environments affect the systemic immunity.

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12 December 2020

A component of polysaccharide peptidoglycan complex on Lactobacillus induced an improvement of murine model of inflammatory bowel disease and colitis-associated cancer

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12 December 2020

Corticotropin-Releasing Factor Regulates TLR4 Expression in the Colon and Protects Mice From Colitis

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12 December 2020

CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice

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12 December 2020

DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma

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12 December 2020

Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemia-reperfusion injury

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12 December 2020

Intestinal alpha-defensin expression in pediatric inflammatory bowel disease

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12 December 2020

Endotoxin and hypoxia-induced intestinal necrosis in rats: the role of platelet activating factor

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12 December 2020

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

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12 December 2020

Protein kinase C iota in the intestinal epithelium protects against dextran sodium sulfate-induced colitis

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12 December 2020

CARD15 Gene Variants and Risk of Reoperation in Crohn's Disease Patients

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12 December 2020

APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells

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12 December 2020

Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis

1 reference

12 December 2020

10.1007/S00018-011-0821-4

Identifiers

DOI

1 reference

25 August 2017

1 reference