(Q37948123)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

LTβR and CD40: working together in dendritic cells to optimize immune responses (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Leslie Summers deLuca

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

publication date

1 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

published in

Immunological Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

85-98

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease

15 January 2020

cites work

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21 January 2018

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Molecular and biological characterization of a murine ligand for CD40

21 January 2018

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CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

21 January 2018

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Monocyte-derived IL12, CD86 (B7-2) and CD40L expression in relapsing and progressive multiple sclerosis.

21 January 2018

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Functions of CD40 on B cells, dendritic cells and other cells

21 January 2018

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High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization

21 January 2018

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CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization

21 January 2018

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TRAF proteins in CD40 signaling

21 January 2018

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TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs

21 January 2018

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Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

21 January 2018

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Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling

21 January 2018

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

21 January 2018

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Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production

21 January 2018

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Inhibition of phosphatidylinositol 3-kinase- and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells

21 January 2018

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A novel mechanism for TNFR-associated factor 6-dependent CD40 signaling

21 January 2018

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Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. I. Characterization of the phenomenon

21 January 2018

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Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

21 January 2018

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Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

21 January 2018

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Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon

21 January 2018

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A lymphotoxin-beta-specific receptor

21 January 2018

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Secondary lymphoid organs: responding to genetic and environmental cues in ontogeny and the immune response

21 January 2018

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Lymph node genesis is induced by signaling through the lymphotoxin beta receptor

21 January 2018

1 reference

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LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator

21 January 2018

1 reference

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Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice

21 January 2018

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The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues

21 January 2018

1 reference

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Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

21 January 2018

1 reference

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The CD160, BTLA, LIGHT/HVEM pathway: a bidirectional switch regulating T-cell activation

21 January 2018

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Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways

21 January 2018

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The lymphotoxin beta receptor is critically involved in controlling infections with the intracellular pathogens Mycobacterium tuberculosis and Listeria monocytogenes.

21 January 2018

1 reference

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Expression of the lymphotoxin beta receptor on follicular stromal cells in human lymphoid tissues

21 January 2018

1 reference

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Lymphotoxin/light, lymphoid microenvironments and autoimmune disease

21 January 2018

1 reference

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Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis

21 January 2018

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TRAF2 plays a key, nonredundant role in LIGHT-lymphotoxin beta receptor signaling

21 January 2018

1 reference

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TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor

21 January 2018

1 reference

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Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor

21 January 2018

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The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

21 January 2018

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

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Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues

21 January 2018

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Lymphotoxin beta receptor induces sequential activation of distinct NF-kappa B factors via separate signaling pathways

21 January 2018

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A fourth IkappaB protein within the NF-kappaB signaling module

21 January 2018

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Affinity maturation without germinal centres in lymphotoxin-alpha-deficient mice.

21 January 2018

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ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction

21 January 2018

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Expression of lymphotoxin-alphabeta on antigen-specific T cells is required for DC function

21 January 2018

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The role of CD40 and CD154/CD40L in dendritic cells

21 January 2018

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The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells

21 January 2018

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Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells.

21 January 2018

1 reference

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LTβR signaling in dendritic cells induces a type I IFN response that is required for optimal clonal expansion of CD8+ T cells

21 January 2018

1 reference

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Different roles for L3T4+ and Lyt 2+ T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Cooperation between helper T cells and cytotoxic T lymphocyte precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

A fail-safe mechanism for maintaining self-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

CD4+ but not CD8+ cells are essential for allorejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Induction of a CD8+ cytotoxic T lymphocyte response by cross-priming requires cognate CD4+ T cell help

21 January 2018

1 reference

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Cooperation between cytotoxic and helper T lymphocytes in protection against lethal Sendai virus infection. Protection by T cells is MHC-restricted and MHC-regulated; a model for MHC-disease associations

21 January 2018

1 reference

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T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.

21 January 2018

1 reference

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Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells

21 January 2018

1 reference

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CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)-T-cell-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Effector and memory CTL differentiation

21 January 2018

1 reference

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Systemic administration of antigen-loaded CD40-deficient dendritic cells mimics soluble antigen administration.

21 January 2018

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Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

21 January 2018

1 reference

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Uncoupling of proliferative potential and gain of effector function by CD8(+) T cells responding to self-antigens.

21 January 2018

1 reference

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Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function

21 January 2018

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Programming for CD8 T cell memory development requires IL-12 or type I IFN

21 January 2018

1 reference

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CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion

21 January 2018

1 reference

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

21 January 2018

1 reference

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Effector T-cell differentiation during viral and bacterial infections: Role of direct IL-12 signals for cell fate decision of CD8(+) T cells

21 January 2018

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Rapid induction of a novel costimulatory activity on B cells by CD40 ligand.

21 January 2018

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

21 January 2018

1 reference

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High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

21 January 2018

1 reference

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Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

21 January 2018

1 reference

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A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

21 January 2018

1 reference

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The role of positive costimulatory molecules in transplantation and tolerance

21 January 2018

1 reference

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Prospect of targeting the CD40 pathway for cancer therapy

21 January 2018

1 reference

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CD40/CD154 interactions at the interface of tolerance and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

21 January 2018

1 reference

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Dendritic cells and the control of immunity

21 January 2018

1 reference

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TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Sustained IL-12 signaling is required for Th1 development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Regulation of the IL-12/IL-12R axis: a critical step in T-helper cell differentiation and effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Interleukin-12 and its role in the generation of TH1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

CD8 T Cell Clonal Expansion and Development of Effector Function Require Prolonged Exposure to Antigen, Costimulation, and Signal 3 Cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Inflammatory cytokines as a third signal for T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Role of lymphotoxin alpha in T-cell responses during an acute viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Lymphotoxin-beta-deficient mice show defective antiviral immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Lymphotoxin-alpha-deficient mice make delayed, but effective, T and B cell responses to influenza.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Lymphotoxin-alpha-deficient mice can clear a productive infection with murine gammaherpesvirus 68 but fail to develop splenomegaly or lymphocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Lymphotoxin alpha-/- mice develop functionally impaired CD8+ T cell responses and fail to contain virus infection of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Reversal of virus-induced systemic shock and respiratory failure by blockade of the lymphotoxin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Blocking lymphotoxin-beta receptor activation diminishes inflammation via reduced mucosal addressin cell adhesion molecule-1 (MAdCAM-1) expression and leucocyte margination in chronic DSS-induced colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Lymphtoxin beta receptor-Ig ameliorates TNBS-induced colitis via blocking LIGHT/HVEM signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Elimination of colonic patches with lymphotoxin beta receptor-Ig prevents Th2 cell-type colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Gene expression profiling of minor salivary glands clearly distinguishes primary Sjögren's syndrome patients from healthy control subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

A role for surface lymphotoxin in experimental autoimmune encephalomyelitis independent of LIGHT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Targeted depletion of lymphotoxin-alpha-expressing TH1 and TH17 cells inhibits autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

The TNF superfamily members LIGHT and CD154 (CD40 ligand) costimulate induction of dendritic cell maturation and elicit specific CTL activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Type I IFNs control antigen retention and survival of CD8α(+) dendritic cells after uptake of tumor apoptotic cells leading to cross-priming

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

IFN-alpha beta promote priming of antigen-specific CD8+ and CD4+ T lymphocytes by immunostimulatory DNA-based vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

CD40 on APCs is needed for optimal programming, maintenance, and recall of CD8+ T cell memory even in the absence of CD4+ T cell help.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Contrasting the roles of costimulation and the natural adjuvant lipopolysaccharide during the induction of T cell immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

IL-21 is required to control chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

IL-21R on T cells is critical for sustained functionality and control of chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

A vital role for interleukin-21 in the control of a chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

TRAF3 and its biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

CD40-mediated activation of NF-kappa B in airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Lymphotoxin-mediated crosstalk between B cells and splenic stroma promotes the initial type I interferon response to cytomegalovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01056.X

10.1111/J.1600-065X.2011.01056.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017433%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference