(Q37948715)

25 August 2017

title

Metabolic engineering for the production of clinically important molecules: Omega-3 fatty acids, artemisinin, and taxol (English)

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25 August 2017

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Victor M Ye

1

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25 August 2017

Sujata K Bhatia

series ordinal

2

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25 August 2017

publication date

21 October 2011

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25 August 2017

published in

Biotechnology Journal

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25 August 2017

volume

7

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25 August 2017

issue

1

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25 August 2017

page(s)

20-33

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Manufacturing molecules through metabolic engineering

25 August 2017

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Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

21 January 2018

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Artemisinins act through at least two targets in a yeast model.

21 January 2018

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Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation

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Anticancer activities of artemisinin and its bioactive derivatives

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Qinghaosu (Artemisinin): The Price of Success

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High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli

21 January 2018

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Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae

21 January 2018

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Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua

21 January 2018

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Overexpression of the HMG-CoA reductase gene leads to enhanced artemisinin biosynthesis in transgenic Artemisia annua plants.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Medicinal chemistry of paclitaxel and its analogues

21 January 2018

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A critical appraisal of the safety and efficacy of drug-eluting stents.

21 January 2018

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Paclitaxel and immune system

21 January 2018

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Paclitaxel-loaded polymeric micelles modified with MCF-7 cell-specific phage protein: enhanced binding to target cancer cells and increased cytotoxicity

21 January 2018

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Palmitoyl ascorbate-modified liposomes as nanoparticle platform for ascorbate-mediated cytotoxicity and paclitaxel co-delivery

21 January 2018

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Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

21 January 2018

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First total synthesis of taxol. 2. Completion of the C and D rings

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100289

First total synthesis of taxol. 1. Functionalization of the B ring

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100289

21 January 2018

Total synthesis of taxol

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100289

21 January 2018

Taxol biosynthetic genes

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100289

Taxol biosynthesis and molecular genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100289

Cytochrome p450 taxadiene 5alpha-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100289

Specificity of the N-benzoyl transferase responsible for the last step of Taxol biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100289

Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100289

Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100289

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100289

Production of isoprenoid pharmaceuticals by engineered microbes

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100289

Engineering of artificial plant cytochrome P450 enzymes for synthesis of isoflavones by Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100289

21 January 2018

Identifiers

DOI

10.1002/BIOT.201100289

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25 August 2017

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