(Q37949258)

25 August 2017

The podocyte cytoskeleton--key to a functioning glomerulus in health and disease (English)

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25 August 2017

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2

Moin A Saleem

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25 August 2017

Gavin I Welsh

1

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PubMed ID

22025085

25 August 2017

language of work or name

English

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publication date

25 October 2011

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Nature Reviews Nephrology

25 August 2017

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25 August 2017

8

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25 August 2017

1

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25 August 2017

14-21

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https://scigraph.springernature.com/pub.10.1038/nrneph.2011.151

25 August 2017

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cites work

Renal handling of albumin: a critical review of basic concepts and perspective

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Complex networks orchestrate epithelial-mesenchymal transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Stretch, tension and adhesion - adaptive mechanisms of the actin cytoskeleton in podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

F-actin fiber distribution in glomerular cells: structural and functional implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Nonuniform microtubular polarity established by CHO1/MKLP1 motor protein is necessary for process formation of podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Human podocytes possess a stretch-sensitive, Ca2+-activated K+ channel: potential implications for the control of glomerular filtration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Mechanical force-activated phospholipase D is mediated by Galpha12/13-Rho and calmodulin-dependent kinase in renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

The human glomerular podocyte is a novel target for insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Bidirectional control of CNS capillary diameter by pericytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Proteinuria: an enzymatic disease of the podocyte?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

A high-powered view of the filtration barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Evidence for restriction of fluid and solute movement across the glomerular capillary wall by the subpodocyte space

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Modification of kidney barrier function by the urokinase receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Actin structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Actin dynamics at the leading edge: from simple machinery to complex networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Actin, a central player in cell shape and movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Coordination of Rho GTPase activities during cell protrusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Slit diaphragm junctional complex and regulation of the cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Nephrin is specifically located at the slit diaphragm of glomerular podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Get to grips: steering local actin dynamics with IQGAPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

p21-activated kinases regulate actin remodeling in glomerular podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Nck proteins maintain the adult glomerular filtration barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Podocin participates in the assembly of tight junctions between foot processes in nephrotic podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

α-actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Mutational and Biological Analysis of alpha-actinin-4 in focal segmental glomerulosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Unleashing formins to remodel the actin and microtubule cytoskeletons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

The inverted Formin INF2 sorts it out.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Mutations in INF2 are a major cause of autosomal dominant focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Microtubule-targeting-dependent reorganization of filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

The shape of motile cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Screening for NPHS2 mutations may help predict FSGS recurrence after transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Circulating permeability factors in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Hemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Three-dimensional analysis of the whole mesangium in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Congenital nephrotic syndrome in mice lacking CD2-associated protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Induction of TRPC6 channel in acquired forms of proteinuric kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2011.151

Nephrin-signature molecule of the glomerular podocyte?

31 March 2020

1 reference

12 December 2020

The glomerular slit diaphragm is a modified adherens junction

1 reference

12 December 2020

A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.

1 reference

12 December 2020

Process formation of podocytes: morphogenetic activity of microtubules and regulation by protein serine/threonine phosphatase PP2A.

1 reference

12 December 2020

Distribution of intermediate filament proteins in normal and diseased human glomeruli

1 reference

12 December 2020

Structure-stabilizing forces in the glomerular tuft.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2011.151

1 reference

PubMed ID

22025085

Dimensions Publication ID

25 August 2017

0 references

1 reference

PubMed ID

22025085