(Q37952439)

25 August 2017

Challenges associated with curcumin therapy in Alzheimer disease (English)

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25 August 2017

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Abdenour Belkacemi

1

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25 August 2017

Sihem Doggui

series ordinal

2

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25 August 2017

Lé Dao

series ordinal

3

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25 August 2017

Charles Ramassamy

series ordinal

4

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25 August 2017

language of work or name

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4 November 2011

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Expert Reviews in Molecular Medicine

25 August 2017

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25 August 2017

13

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25 August 2017

e34

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Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro

25 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa).

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

The p60 tumor necrosis factor (TNF) receptor-associated kinase (TRAK) binds residues 344-397 within the cytoplasmic domain involved in TNF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Bisdemethylcurcumin and structurally related hispolon analogues of curcumin exhibit enhanced prooxidant, anti-proliferative and anti-inflammatory activities in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcuminoids, curcumin, and demethoxycurcumin reduce lead-induced memory deficits in male Wistar rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin-derived transients: a pulsed laser and pulse radiolysis study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin and its analogues as potent inhibitors of low density lipoprotein oxidation: H-atom abstraction from the phenolic groups and possible involvement of the 4-hydroxy-3-methoxyphenyl groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Structure-radical scavenging activity relationships of phenolic compounds from traditional Chinese medicinal plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Fluorescence study of the curcumin-casein micelle complexation and its application as a drug nanocarrier to cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Differential effects of curcumin on vasoactive factors in the diabetic rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Synthesis and in vitro/in vivo anti-cancer evaluation of curcumin-loaded chitosan/poly(butyl cyanoacrylate) nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Ameliorating effect of curcumin on sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin prevents oxidative renal damage induced by acetaminophen in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin prevents adriamycin nephrotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

The in vitro stability and in vivo pharmacokinetics of curcumin prepared as an aqueous nanoparticulate formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin as "Curecumin": from kitchen to clinic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Challenges for research on polyphenols from foods in Alzheimer's disease: bioavailability, metabolism, and cellular and molecular mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Bioavailability of curcumin: problems and promises

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin nanodisks: formulation and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Evaluation of an oral carrier system in rats: bioavailability and antioxidant properties of liposome-encapsulated curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Development and evaluation of self-microemulsifying liquid and pellet formulations of curcumin, and absorption studies in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Bioavailability enhancement of curcumin by complexation with phosphatidyl choline

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin labeling of neuronal fibrillar tau inclusions in human brain samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Modulation of anxiety behavior by intranasally administered vaccinia virus complement control protein and curcumin in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Biochemical markers in persons with preclinical familial Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Molecular mechanisms of aging-associated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Oxidative damage in Alzheimer's.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Synthesis and characterization of a cytotoxic cationic polyvinylpyrrolidone-curcumin conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Dimethoxycurcumin, a Synthetic Curcumin Analogue, Induces Heme Oxygenase-1 Expression through Nrf2 Activation in RAW264.7 Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Therapeutic perspectives in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease: prospects, limitations and strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Identification of permeability-related hurdles in oral delivery of curcumin using the Caco-2 cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Neurotoxicological effects and the impairment of spatial recognition memory in mice caused by exposure to TiO2 nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

TiO2 nanoparticles promote beta-amyloid fibrillation in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Potential neurotoxicity of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Biodegradable nanoparticles for drug and gene delivery to cells and tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

ApoE3 mediated poly(butyl) cyanoacrylate nanoparticles containing curcumin: study of enhanced activity of curcumin against beta amyloid induced cytotoxicity using in vitro cell culture model

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Apolipoprotein E LDL receptor-binding domain-containing high-density lipoprotein: a nanovehicle to transport curcumin, an antioxidant and anti-amyloid bioflavonoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Stability of curcumin in buffer solutions and characterization of its degradation products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Stability-indicating HPTLC determination of curcumin in bulk drug and pharmaceutical formulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Effects of curcumin on P-glycoprotein in primary cultures of rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Drug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

The functions of the amyloid precursor protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Regulation of APP cleavage by alpha-, beta- and gamma-secretases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Dementia and Alzheimer disease incidence: a prospective cohort study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Global prevalence of dementia: a Delphi consensus study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

Absorption and tissue distribution of curcumin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Severe motor neuron degeneration in the spinal cord of the Tg2576 mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Curcuminoid binds to amyloid-β1-42 oligomer and fibril

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Curcuminoids as potent inhibitors of lipid peroxidation

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Nematocidal activity of turmeric: synergistic action of curcuminoids

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Neuroprotective and neurorescue effects of a novel polymeric nanoparticle formulation of curcumin (NanoCurc™) in the neuronal cell culture and animal model: implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Role of capsaicin, curcumin and dietary n-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Ten-year incidence of dementia in a rural elderly US community population: the MoVIES Project

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Curcumin-loaded PLGA-PEG-PLGA triblock copolymeric micelles: Preparation, pharmacokinetics and distribution in vivo

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Reactions of reactive oxygen species (ROS) with curcumin analogues: Structure-activity relationship

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Effect of tetrahydrocurcumin on lipid peroxidation and lipids in streptozotocin-nicotinamide-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and blood-brain barrier transport of circulating Alzheimer's amyloid beta.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002055

7 January 2021

https://api.crossref.org/works/10.1017%2FS1462399411002055

1 reference

7 January 2021

10.1017/S1462399411002055

Identifiers

DOI

1 reference

25 August 2017

1 reference