(Q37956599)

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Inflamm-aging of the stem cell niche: breast cancer as a paradigmatic example: breakdown of the multi-shell cytokine network fuels cancer in aged people

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 August 2017

Inflamm-aging of the stem cell niche: breast cancer as a paradigmatic example: breakdown of the multi-shell cytokine network fuels cancer in aged people (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

stem cell niche

1 reference

based on heuristic

inferred from title

Gianluca Storci

2

object named as

Gianluca Storci

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

Claudio Franceschi

3

object named as

Claudio Franceschi

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

author name string

Massimiliano Bonafè

1

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

language of work or name

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publication date

16 November 2011

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Europe PubMed Central

PubMed publication ID

25 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

34

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

40-49

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

Inflamm-aging. An evolutionary perspective on immunosenescence

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Centenarians as a model for healthy aging

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

1 reference

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21 January 2018

Inflammation and cancer: back to Virchow?

1 reference

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21 January 2018

Inflammation and cancer

1 reference

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21 January 2018

Innate immune inflammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice

1 reference

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21 January 2018

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Four faces of cellular senescence.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The senescence-associated secretory phenotype: the dark side of tumor suppression

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Significance of interleukin-6 (IL-6) in breast cancer (review).

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Normal stem cells and cancer stem cells: the niche matters

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Origin and physiological roles of inflammation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Resident macrophages influence stem cell activity in the mammary gland

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The aging gut microbiota: new perspectives

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Aging of the human metaorganism: the microbial counterpart

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Inflammatory mechanisms in obesity

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Disrupting the stem cell niche: good seeds in bad soil.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Stem cell regulatory niches and their role in normal and malignant hematopoiesis

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Strategies for homeostatic stem cell self-renewal in adult tissues

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Cytokine signalling in mammary gland development

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Aging, frailty and age-related diseases

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Para-inflammation mediates systemic DNA damage in response to tumor growth

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individuals

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Radiation induced non-targeted response: mechanism and potential clinical implications

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Medium-mediated DNA repair response after ionizing radiation is correlated with the increase of specific cytokines in human fibroblasts.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Radiation-induced bystander signaling pathways in human fibroblasts: a role for interleukin-33 in the signal transmission

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Evolution of the mammary gland from the innate immune system?

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Prospective identification of tumorigenic breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Inflammation and cancer: The oncogene-driven connection

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Fibroblasts in cancer

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Stromal fibroblasts in cancer initiation and progression

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Jekyll and Hyde: the role of the microenvironment on the progression of cancer

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

SA beta Gal staining: biomarker or delusion

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Genetic changes in tumour microenvironments

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Mutations in bone marrow-derived stromal stem cells unmask latent malignancy

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Coevolution of cancer and stromal cellular responses

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Identification of human papillomavirus DNA gene sequences in human breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

The mammary gland microenvironment directs progenitor cell fate in vivo

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Inflammation and mesenchymal stem cell aging

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Mechanisms of hematopoietic stem cell aging

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Aging of hematopoietic stem cells: Intrinsic changes or micro-environmental effects?

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Hemopoiesis in healthy old people and centenarians: well-maintained responsiveness of CD34+ cells to hemopoietic growth factors and remodeling of cytokine network.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Myeloid Malignancies and the Marrow Microenvironment: Some Recent Studies in Patients with MDS

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

DNA damage-mediated induction of a chemoresistant niche

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Linking functional decline of telomeres, mitochondria and stem cells during ageing

1 reference

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21 January 2018

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Genomic Alterations in Tumor Stroma

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100104

21 January 2018

Identifiers

10.1002/BIES.201100104

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

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