(Q37957798)

25 August 2017

title

Molecular alterations in hepatocarcinogenesis induced by dietary methyl deficiency (English)

1 reference

25 August 2017

Frederick A Beland

3

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author name string

Igor P Pogribny

series ordinal

1

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25 August 2017

S Jill James

series ordinal

2

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25 August 2017

publication date

17 November 2011

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Molecular Nutrition and Food Research

25 August 2017

published in

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25 August 2017

volume

56

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25 August 2017

issue

1

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25 August 2017

page(s)

116-125

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The role of nutrition in cancer development and prevention

25 August 2017

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Metabolic regulatory properties of S-adenosylmethionine and S-adenosylhomocysteine

21 January 2018

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Folic acid deficiency and cancer: mechanisms of DNA instability

21 January 2018

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One-carbon metabolism-genome interactions in folate-associated pathologies

21 January 2018

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Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.

21 January 2018

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Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency

21 January 2018

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Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

21 January 2018

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Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis.

21 January 2018

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Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat

21 January 2018

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Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine

21 January 2018

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Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.

21 January 2018

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Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

21 January 2018

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Hepatic free fatty acids accumulate in experimental steatohepatitis: role of adaptive pathways

21 January 2018

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1,2-sn-diacylglycerol accumulates in choline-deficient liver. A possible mechanism of hepatic carcinogenesis via alteration in protein kinase C activity?

21 January 2018

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Effects of prolonged (1 year) choline deficiency and subsequent re-feeding of choline on 1,2-sn-diradylglycerol, fatty acids and protein kinase C in rat liver.

21 January 2018

1 reference

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Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1.

21 January 2018

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Transcriptional profile of genes involved in oxidative stress and antioxidant defense in a dietary murine model of steatohepatitis

21 January 2018

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Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism

21 January 2018

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Nitric oxide and redox regulation in the liver: Part I. General considerations and redox biology in hepatitis

21 January 2018

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Oxidative activation of antioxidant defence

21 January 2018

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Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria.

21 January 2018

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Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet.

21 January 2018

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CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

21 January 2018

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Lipid peroxidation in mice fed a choline-deficient diet as evaluated by total hydroxyoctadecadienoic acid

21 January 2018

1 reference

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Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets

21 January 2018

1 reference

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Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.

21 January 2018

1 reference

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Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model

21 January 2018

1 reference

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Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention

21 January 2018

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Endogenous liver carcinogenesis in the rat.

21 January 2018

1 reference

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Role of DNA damage and alterations in cytosine DNA methylation in rat liver carcinogenesis induced by a methyl-deficient diet.

21 January 2018

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Expression of base excision DNA repair genes as a biomarker of oxidative DNA damage.

21 January 2018

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Reactive oxygen species (ROS)--induced genetic and epigenetic alterations in human carcinogenesis.

21 January 2018

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Oxidative stress and cancer: have we moved forward?

21 January 2018

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Presence and consequence of uracil in preneoplastic DNA from folate/methyl-deficient rats.

21 January 2018

1 reference

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Alterations in nucleotide pools in rats fed diets deficient in choline, methionine and/or folic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Apoptosis and proliferation under conditions of deoxynucleotide pool imbalance in liver of folate/methyl deficient rats.

21 January 2018

1 reference

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Uracil in DNA: consequences for carcinogenesis and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Genomic hypomethylation is specific for preneoplastic liver in folate/methyl deficient rats and does not occur in non-target tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Advances in DNA methylation: 5-hydroxymethylcytosine revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Large-scale structure of genomic methylation patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

DNA methylation landscapes: provocative insights from epigenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

The history of cancer epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Global DNA hypomethylation in liver cancer cases and controls: a phase I preclinical biomarker development study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Genome-wide DNA methylation profiles in precancerous conditions and cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

LINE-1 hypomethylation in a choline-deficiency-induced liver cancer in rats: dependence on feeding period

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Identification of differentially methylated sites within unmethylated DNA domains in normal and cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Epigenetic regulation of telomeres in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

CpG site hypermethylation of E-cadherin and Connexin26 genes in hepatocellular carcinomas induced by a choline-deficient L-Amino Acid-defined diet in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Coupling global methylation and gene expression profiles reveal key pathophysiological events in liver injury induced by a methyl-deficient diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Chromatin modifications and their function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Regulation of chromatin by histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Requirement of RIZ1 for cancer prevention by methyl-balanced diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Heterochromatin and tri-methylated lysine 20 of histone H4 in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

The epigenetic magic of histone lysine methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Chromatin landscape: methylation beyond transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Determination of enriched histone modifications in non-genic portions of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Downregulation of miR-122 in the rodent and human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

MicroRNA involvement in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Targeting DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Targeting DNA methylation for epigenetic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

An overview of epigenetics and chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Histone methyl transferases and demethylases; can they link metabolism and transcription?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

Epidemiologic studies of nutrition and cancer: Let us not throw out the baby with the bath water

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100524

21 January 2018

Identifiers

DOI

10.1002/MNFR.201100524

1 reference

25 August 2017

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