(Q37960450)

20 February 2018

title

Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins (English)

1 reference

20 February 2018

author name string

Ariel H Polizio

1

1 reference

20 February 2018

Pilar Chinchilla

2

1 reference

20 February 2018

Xiaolen Chen

3

1 reference

20 February 2018

David R Manning

4

1 reference

20 February 2018

Natalia A Riobo

5

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20 February 2018

publication date

22 November 2011

1 reference

20 February 2018

published in

Science Signaling

1 reference

20 February 2018

volume

4

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20 February 2018

issue

200

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20 February 2018

page(s)

pt7

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20 February 2018

Heterotrimeric Gi proteins link Hedgehog signaling to activation of Rho small GTPases to promote fibroblast migration

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complex

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Activation of heterotrimeric G proteins by Smoothened

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Purmorphamine activates the Hedgehog pathway by targeting Smoothened.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Vertebrate Smoothened functions at the primary cilium

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Small molecule modulation of Smoothened activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Analysis of G protein activation in Sf9 and mammalian cells by agonist-promoted [35S]GTP gamma S binding

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5811764

10.1126/SCISIGNAL.2002396

1 September 2018

Identifiers

DOI

1 reference

20 February 2018

PMC publication ID

5811764

1 reference

20 February 2018

PubMed publication ID

22114142

1 reference

20 February 2018