(Q37967484)

26 August 2017

Mendelian randomization: application to cardiovascular disease (English)

1 reference

26 August 2017

cardiovascular disease

1 reference

1

1 reference

26 August 2017

George Davey Smith

3

0 references

Kaitlin H Wade

object named as

Kaitlin H Wade

series ordinal

2

0 references

publication date

1 February 2012

1 reference

Current Hypertension Reports

26 August 2017

1 reference

26 August 2017

14

1 reference

26 August 2017

1

1 reference

26 August 2017

29-37

1 reference

https://scigraph.springernature.com/pub.10.1007/s11906-011-0242-7

26 August 2017

0 references

cites work

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Mendelian randomization: prospects, potentials, and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

An introduction to instrumental variables for epidemiologists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Common variants near MC4R are associated with fat mass, weight and risk of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Alcohol and blood pressure: the INTERSALT study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

The detection, treatment and control of high blood pressure in older British adults: cross-sectional findings from the British Women's Heart and Health Study and the British Regional Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Alcohol consumption and the incidence of hypertension: The Atherosclerosis Risk in Communities Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Alcohol consumption and blood pressure in the 1982 Maryland Hypertension Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Epidemiologic study of the association of low-Km mitochondrial acetaldehyde dehydrogenase genotypes with blood pressure level and the prevalence of hypertension in a general population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

The aldehyde dehydrogenase 2 gene is a risk factor for hypertension in Japanese but does not alter the sensitivity to pressor effects of alcohol: the Suita study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

C-reactive protein and its role in metabolic syndrome: mendelian randomisation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Targeting C-reactive protein for the treatment of cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Sorting out cholesterol and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Biological, clinical and population relevance of 95 loci for blood lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

What can human genetics teach us about the causes of cardiovascular disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genetically elevated lipoprotein(a) and increased risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Extreme lipoprotein(a) levels and risk of myocardial infarction in the general population: the Copenhagen City Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Subjects heterozygous for genetic loss of function of the thiazide-sensitive cotransporter have reduced blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Still building on candidate-gene strategy in hypertension?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Uric acid: role in cardiovascular disease and effects of losartan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

The association between serum uric acid level and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Magnitude of sustained multiple risk factors for ischemic heart disease in Japanese employees: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Hyperuricemia and risk of stroke: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

A 'complexity' of urate transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Bayesian methods for instrumental variable analysis with genetic instruments ('Mendelian randomization'): example with urate transporter SLC2A9 as an instrumental variable for effect of urate levels on metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Diabetes and cardiovascular disease. The Framingham study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Variants in MTNR1B influence fasting glucose levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Mendelian randomisation and causal inference in observational epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Avoiding bias from weak instruments in Mendelian randomization studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Impact of Mendelian inheritance in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Association between C-reactive protein and features of the metabolic syndrome: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Association of C-Reactive Protein With Blood Pressure and Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Uric Acid Levels Are Associated With All-Cause and Cardiovascular Disease Mortality Independent of Systemic Inflammation in Men From the General Population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-011-0242-7

Hyperuricemia and coronary heart disease: a systematic review and meta-analysis.

21 January 2018

1 reference

12 December 2020

Selective Genotyping Reveals Association Between the Epithelial Sodium Channel γ-Subunit and Systolic Blood Pressure

1 reference

12 December 2020

Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study

1 reference

12 December 2020

Salt and hypertension

1 reference

12 December 2020

Effect of longer-term modest salt reduction on blood pressure

1 reference

12 December 2020

Hemostatic abnormalities associated with obesity and the metabolic syndrome.

1 reference

12 December 2020

Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes

1 reference

12 December 2020

Mendelian randomisation, triglycerides, and CHD

1 reference

12 December 2020

Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans

1 reference

12 December 2020

Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: the Copenhagen City Heart Study with 31 years of follow-up

1 reference

12 December 2020

Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey

1 reference

12 December 2020

Genetics of coronary artery disease

1 reference

12 December 2020

Genome-wide association studies of plasma lipids: have we reached the limit?

1 reference

12 December 2020

Altered dietary salt intake for preventing and treating diabetic kidney disease

1 reference

12 December 2020

C reactive protein and the risk of cardiovascular disease

1 reference

12 December 2020

Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. Intersalt Cooperative Research Group

1 reference

12 December 2020

Banting lecture 1988. Role of insulin resistance in human disease

1 reference

12 December 2020

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

1 reference

12 December 2020

1 reference

12 December 2020

Nature's randomised trials

1 reference

12 December 2020

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

1 reference

12 December 2020

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride

1 reference

12 December 2020

10.1007/S11906-011-0242-7

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22161218