(Q37979639)

26 August 2017

title

Multiple roles of class I HDACs in proliferation, differentiation, and development (English)

1 reference

26 August 2017

Nina Reichert

1

1 reference

26 August 2017

Mohamed-Amin Choukrallah

series ordinal

2

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26 August 2017

Patrick Matthias

series ordinal

3

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26 August 2017

language of work or name

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1 July 2012

1 reference

Cellular and Molecular Life Sciences

26 August 2017

published in

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26 August 2017

volume

69

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26 August 2017

issue

13

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26 August 2017

page(s)

2173-2187

1 reference

https://scigraph.springernature.com/pub.10.1007/s00018-012-0921-9

26 August 2017

exact match

0 references

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Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression

21 January 2018

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Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

21 January 2018

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Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility

21 January 2018

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Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity

21 January 2018

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Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice.

21 January 2018

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HDAC2 negatively regulates memory formation and synaptic plasticity.

21 January 2018

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Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control

21 January 2018

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Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

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Epigenetic control of skull morphogenesis by histone deacetylase 8

21 January 2018

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Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis

21 January 2018

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Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells

21 January 2018

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Role for histone deacetylase 1 in human tumor cell proliferation

21 January 2018

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Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

21 January 2018

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Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells

21 January 2018

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Histone deacetylase 1 can repress transcription by binding to Sp1.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Retinoblastoma protein recruits histone deacetylase to repress transcription

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Retinoblastoma protein transcriptional repression through histone deacetylation of a single nucleosome

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Epigenetic regulation of vascular smooth muscle cell proliferation and neointima formation by histone deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Acetylation is indispensable for p53 activation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Regulation of E2F1 activity by acetylation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

The specific role of histone deacetylase 2 in adult neurogenesis.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Redundant control of adipogenesis by histone deacetylases 1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Inhibition of histone deacetylase in cancer cells slows down replication forks, activates dormant origins, and induces DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Hdac3 is essential for the maintenance of chromatin structure and genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

HDAC3 is a critical negative regulator of long-term memory formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone deacetylase 8 in neuroblastoma tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Inactivation of CREB mediated gene transcription by HDAC8 bound protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Expression profile of histone deacetylase 1 in gastric cancer tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Increased expression of histone deacetylase 2 is found in human gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Comparative application of antibody and gene array for expression profiling in human squamous cell lung carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone Deacetylase Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Inhibitory effect of cucurbitacin E on pancreatic cancer cells growth via STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Anticancer activities of histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone deacetylase inhibitors, anticancerous mechanism and therapy for gastrointestinal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone deacetylase inhibitors: from target to clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Tolerability, pharmacodynamics, and pharmacokinetics studies of depsipeptide (romidepsin) in patients with acute myelogenous leukemia or advanced myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Clinical and molecular responses in lung cancer patients receiving Romidepsin

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Final results from a multicenter, international, pivotal study of romidepsin in refractory cutaneous T-cell lymphoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Chemical phylogenetics of histone deacetylases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Romidepsin: a new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Novel anticancer targets and drug discovery in post genomic age.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

HDAC inhibitors as anti-inflammatory agents

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Targeting the correct HDAC(s) to treat cognitive disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

A phase 1 pharmacokinetic and pharmacodynamic study of the histone deacetylase inhibitor belinostat in patients with advanced solid tumors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex

21 January 2018

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LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

21 January 2018

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MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

CoREST is an integral component of the CoREST- human histone deacetylase complex

21 January 2018

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N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-0921-9

The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2

21 January 2018

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A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

21 January 2018

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12 December 2020

Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer

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12 December 2020

Genetic approaches to investigate the role of CREB in neuronal plasticity and memory.

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12 December 2020

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

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12 December 2020

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms

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12 December 2020

Cardiac studies in patients treated with depsipeptide, FK228, in a phase II trial for T-cell lymphoma

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12 December 2020

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

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12 December 2020

Meiotic events at the centromeric heterochromatin: histone H3 phosphorylation, topoisomerase II alpha localization and chromosome condensation

1 reference

12 December 2020

Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity.

1 reference

12 December 2020

p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells.

1 reference

12 December 2020

Histone deacetylase 3 regulates smooth muscle differentiation in neural crest cells and development of the cardiac outflow tract

1 reference

12 December 2020

10.1007/S00018-012-0921-9

Identifiers

DOI

1 reference

26 August 2017

1 reference