(Q37981008)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301438%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Cardiac gene therapy in large animals: bridge from bench to bedside (English)

1 reference

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22 January 2020

0 references

4

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22 January 2020

author name string

K Ishikawa

1

1 reference

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22 January 2020

L Tilemann

2

1 reference

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22 January 2020

D Ladage

3

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22 January 2020

L Leonardson

5

1 reference

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22 January 2020

K Fish

6

1 reference

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22 January 2020

Y Kawase

7

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22 January 2020

publication date

2 February 2012

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22 January 2020

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22 January 2020

volume

19

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22 January 2020

issue

6

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22 January 2020

page(s)

670-677

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Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure

22 January 2020

cites work

1 reference

Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes

21 January 2018

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Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a

21 January 2018

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Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation

21 January 2018

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Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals

21 January 2018

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SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells

21 January 2018

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Gene transfection of hepatocyte growth factor attenuates cardiac remodeling in the canine heart: A novel gene therapy for cardiomyopathy

21 January 2018

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Gene transfection with human hepatocyte growth factor complementary DNA plasmids attenuates cardiac remodeling after acute myocardial infarction in goat hearts implanted with ventricular assist devices

21 January 2018

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Plasmid-mediated VEGF gene transfer induces cardiomyogenesis and reduces myocardial infarct size in sheep

21 January 2018

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Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms.

21 January 2018

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Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart

21 January 2018

1 reference

Adenoviral gene transfer of FGF-5 to hibernating myocardium improves function and stimulates myocytes to hypertrophy and reenter the cell cycle

21 January 2018

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Local transient myocardial liposomal gene transfer of inducible nitric oxide synthase does not aggravate myocardial function and fibrosis and leads to moderate neovascularization in chronic myocardial ischemia in pigs

21 January 2018

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Gene therapy in cardiac surgery: intramyocardial injection of naked plasmid DNA for chronic myocardial ischemia

21 January 2018

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Development of a preclinical model of ischemic cardiomyopathy in swine

21 January 2018

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Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy

21 January 2018

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Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals

21 January 2018

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Augmentation of left ventricular mechanics by recirculation-mediated AAV2/1-SERCA2a gene delivery in experimental heart failure

21 January 2018

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Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure

21 January 2018

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Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure

21 January 2018

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Molecular ablation of ventricular tachycardia after myocardial infarction

21 January 2018

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Epicardial border zone overexpression of skeletal muscle sodium channel SkM1 normalizes activation, preserves conduction, and suppresses ventricular arrhythmia: an in silico, in vivo, in vitro study

21 January 2018

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Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model

21 January 2018

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Adenoviral gene transfer of HCN4 creates a genetic pacemaker in pigs with complete atrioventricular block

21 January 2018

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Adenylate-cyclase VI transforms ventricular cardiomyocytes into biological pacemaker cells.

21 January 2018

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Heart failure with preserved systolic function. A different natural history?

21 January 2018

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Comparative analysis of parvalbumin and SERCA2a cardiac myocyte gene transfer in a large animal model of diastolic dysfunction

21 January 2018

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High-energy phosphate metabolism and creatine kinase in failing hearts: a new porcine model

21 January 2018

1 reference

Therapeutic angiogenesis for cardiovascular disease: biological context, challenges, prospects

21 January 2018

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Vascular endothelial growth factor-165 gene therapy promotes cardiomyogenesis in reperfused myocardial infarction

21 January 2018

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Cardiomyocyte hyperplasia after plasmid-mediated vascular endothelial growth factor gene transfer in pigs with chronic myocardial ischemia

21 January 2018

1 reference

Intramyocardial gene therapy with naked DNA encoding vascular endothelial growth factor improves collateral flow to ischemic myocardium

21 January 2018

1 reference

Entrance in mitosis of adult cardiomyocytes in ischemic pig hearts after plasmid-mediated rhVEGF165 gene transfer

21 January 2018

1 reference

Effects of intramyocardial pVEGF165 delivery on regional myocardial blood flow: evidence for a spatial 'delivery-efficacy' mismatch

21 January 2018

1 reference

Complete reversal of ischemic wall motion abnormalities by combined use of gene therapy with transmyocardial laser revascularization

21 January 2018

1 reference

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart

21 January 2018

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Increased regional function and perfusion after intracoronary delivery of adenovirus encoding fibroblast growth factor 4: report of preclinical data

21 January 2018

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Myocardial transfection with naked DNA plasmid encoding hepatocyte growth factor prevents the progression of heart failure in dogs

21 January 2018

1 reference

Angiogenic and antifibrotic actions of hepatocyte growth factor improve cardiac dysfunction in porcine ischemic cardiomyopathy.

21 January 2018

1 reference

Recruitment of stem cells by hepatocyte growth factor via intracoronary gene transfection in the postinfarction heart failure.

21 January 2018

1 reference

Therapeutic angiogenesis using naked DNA expressing two isoforms of the hepatocyte growth factor in a porcine acute myocardial infarction model.

21 January 2018

1 reference

Quantitative MR measurements of regional and global left ventricular function and strain after intramyocardial transfer of VM202 into infarcted swine myocardium

21 January 2018

1 reference

Treatment of chronical myocardial ischemia by adenovirus-mediated hepatocyte growth factor gene transfer in minipigs

21 January 2018

1 reference

CD151 gene delivery after myocardial infarction promotes functional neovascularization and activates FAK signaling

21 January 2018

1 reference

The efficacy of a 'master switch gene' HIF-1alpha in a porcine model of chronic myocardial ischaemia

21 January 2018

1 reference

Targeting myocardial beta-adrenergic receptor signaling and calcium cycling for heart failure gene therapy

21 January 2018

1 reference

beta2 adrenoceptor gene therapy ameliorates left ventricular dysfunction following cardiac surgery

21 January 2018

1 reference

Dose dependent effects of cardiac beta2 adrenoceptor gene therapy

21 January 2018

1 reference

Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

21 January 2018

1 reference

Molecular enhancement of porcine cardiac chronotropy

21 January 2018

1 reference

Focal modification of electrical conduction in the heart by viral gene transfer

21 January 2018

1 reference

Inhibitory G protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation

21 January 2018

1 reference

The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases

21 January 2018

1 reference

Attenuation of endoplasmic reticulum stress-related myocardial apoptosis by SERCA2a gene delivery in ischemic heart disease

21 January 2018

1 reference

Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines

21 January 2018

1 reference

Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model

21 January 2018

1 reference

Gene therapy strategies for cardiac electrical dysfunction

21 January 2018

1 reference

Selective molecular potassium channel blockade prevents atrial fibrillation

21 January 2018

1 reference

Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model

21 January 2018

1 reference

Biological pacemaker implanted in canine left bundle branch provides ventricular escape rhythms that have physiologically acceptable rates

21 January 2018

1 reference

Expression and function of a biological pacemaker in canine heart

21 January 2018

1 reference

Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.

21 January 2018

1 reference

Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial reperfusion injury

21 January 2018

1 reference

Retroinfusion of NFkappaB decoy oligonucleotide extends cardioprotection achieved by CD18 inhibition in a preclinical study of myocardial ischemia and retroinfusion in pigs

21 January 2018

1 reference

Myocarditis following adeno-associated viral gene expression of human soluble TNF receptor (TNFRII-Fc) in baboon hearts.

21 January 2018

1 reference

Targeted nNOS gene transfer into the cardiac vagus rapidly increases parasympathetic function in the pig.

21 January 2018

1 reference

Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models

21 January 2018

1 reference

Delivery of gelfoam-enabled cells and vectors into the pericardial space using a percutaneous approach in a porcine model

21 January 2018

1 reference

Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors

21 January 2018

1 reference

Ex vivo gene transfer of basic fibroblast growth factor improves cardiac function and blood flow in a swine chronic myocardial ischemia model

21 January 2018

1 reference

Overexpression of p53 increases lumen size and blocks neointima formation in porcine interposition vein grafts

21 January 2018

1 reference

Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure

21 January 2018

1 reference

7 January 2021

Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion

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7 January 2021

Induction of collateral artery growth and improvement of post-infarct heart function by hepatocyte growth factor gene transfer

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7 January 2021

Comparison of protein with DNA therapy for chronic myocardial ischemia using fibroblast growth factor-2

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7 January 2021

Xenografted adult human mesenchymal stem cells provide a platform for sustained biological pacemaker function in canine heart

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7 January 2021

Mortality and readmission of hospitalized patients with congestive heart failure and preserved versus depressed systolic function

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7 January 2021

Load versus humoral activation in the genesis of early hypertensive heart disease

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7 January 2021

Effects of therapeutic angiogenesis with plasmid VEGF165 on ventricular function in a canine model of chronic myocardial infarction

1 reference

7 January 2021

Adenoviral-mediated gene transfer induces sustained pericardial VEGF expression in dogs: effect on myocardial angiogenesis

1 reference

7 January 2021

Efficacy of therapeutic angiogenesis by intramyocardial injection of pCK-VEGF165 in pigs

1 reference

7 January 2021

Angiopoietin-1 promotes functional neovascularization that relieves ischemia by improving regional reperfusion in a swine chronic myocardial ischemia model

1 reference

7 January 2021

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

1 reference

7 January 2021

Gene transfer of hepatocyte growth factor improves angiogenesis and function of chronic ischemic myocardium in canine heart

1 reference

7 January 2021

Improvement of heart function in postinfarct heart failure swine models after hepatocyte growth factor gene transfer: comparison of low-, medium- and high-dose groups

1 reference

7 January 2021

Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein

1 reference

7 January 2021

Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level

1 reference

7 January 2021

Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity

1 reference

7 January 2021

Improved cardiac function after sarcoplasmic reticulum Ca(2+)-ATPase gene transfer in a heart failure model induced by chronic myocardial ischaemia

1 reference

7 January 2021

Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

1 reference

7 January 2021

Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go-related gene mutant

1 reference

7 January 2021

Suppression of persistent atrial fibrillation by genetic knockdown of caspase 3: a pre-clinical pilot study

1 reference

7 January 2021

Identifiers

DOI

10.1038/GT.2012.3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301438%20AND%20SRC:MED&resulttype=core&format=json

release_263g5rylsjg2nasknb2nqfz6yq

22 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/263g5rylsjg2nasknb2nqfz6yq

24 November 2022

mapped directly with Wikidata item

1 reference