(Q37982821)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Oligonucleotide-directed gene-editing technology: mechanisms and future prospects (English)

1 reference

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22 January 2020

2

1 reference

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22 January 2020

author name string

Ioannis Papaioannou

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

James S Owen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

10 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Biological Therapy

22 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

329-342

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

Progress and prospects: targeted gene alteration (TGA).

22 January 2020

cites work

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Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty

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Failure to achieve gene conversion with chimeric circular oligonucleotides: potentially misleading PCR artifacts observed

21 January 2018

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Failure to generate atheroprotective apolipoprotein AI phenotypes using synthetic RNA/DNA oligonucleotides (chimeraplasts).

21 January 2018

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Transformation of yeast with synthetic oligonucleotides

21 January 2018

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The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extracts

21 January 2018

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Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells

21 January 2018

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Targeted gene modification in mismatch-repair-deficient embryonic stem cells by single-stranded DNA oligonucleotides

21 January 2018

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A LacZ-based transgenic mouse for detection of somatic gene repair events in vivo.

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Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends

21 January 2018

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Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells.

21 January 2018

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Physical incorporation of a single-stranded oligodeoxynucleotide during targeted repair of a human chromosomal locus

21 January 2018

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Single-strand DNA-mediated targeted mutagenesis of genomic DNA in early mouse embryos is stimulated by Rad51/54 and by Ku70/86 inhibition

21 January 2018

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Oligonucleotide-mediated gene targeting in human hepatocytes: implications of mismatch repair

21 January 2018

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Validation of oligonucleotide-mediated gene editing.

21 January 2018

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Use of internally nuclease-protected single-strand DNA oligonucleotides and silencing of the mismatch repair protein, MSH2, enhances the replication of corrected cells following gene editing

21 January 2018

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Strand bias in oligonucleotide-mediated dystrophin gene editing

21 January 2018

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Implications of cell cycle progression on functional sequence correction by short single-stranded DNA oligonucleotides

21 January 2018

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Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cells

21 January 2018

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A plausible mechanism for gene correction by chimeric oligonucleotides

21 January 2018

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Mechanism of gene repair open for discussion

21 January 2018

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Subtle gene modification in mouse ES cells: evidence for incorporation of unmodified oligonucleotides without induction of DNA damage

21 January 2018

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Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

21 January 2018

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Transfection and homologous recombination involving single-stranded DNA substrates in mammalian cells and nuclear extracts

21 January 2018

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Simultaneous targeted alteration of the tyrosinase and c-kit genes by single-stranded oligonucleotides

21 January 2018

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Unmodified oligodeoxynucleotides require single-strandedness to induce targeted repair of a chromosomal EGFP gene

21 January 2018

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Recovery of cell cycle delay following targeted gene repair by oligonucleotides

21 January 2018

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Differential cellular responses to exogenous DNA in mammalian cells and its effect on oligonucleotide-directed gene modification

21 January 2018

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Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases

21 January 2018

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DNA breakage associated with targeted gene alteration directed by DNA oligonucleotides

21 January 2018

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Oligonucleotide-mediated gene editing is underestimated in cells expressing mutated green fluorescent protein and is positively associated with target protein expression

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Single-stranded oligonucleotide-mediated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair.

21 January 2018

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Different S/M checkpoint responses of tumor and non tumor cell lines to DNA replication inhibition

21 January 2018

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Mechanisms in eukaryotic mismatch repair

21 January 2018

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Roles for mismatch repair factors in regulating genetic recombination

21 January 2018

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Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Gene targeting using zinc finger nucleases

21 January 2018

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Mammalian gene targeting with designed zinc finger nucleases

21 January 2018

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Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

21 January 2018

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

21 January 2018

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Knockout rats via embryo microinjection of zinc-finger nucleases

21 January 2018

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Selection-independent generation of gene knockout mouse embryonic stem cells using zinc-finger nucleases

21 January 2018

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Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

21 January 2018

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Zinc-finger nucleases: how to play two good hands

21 January 2018

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21 January 2018

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Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

21 January 2018

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21 January 2018

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Targeted chromosomal gene modification in human cells by single-stranded oligodeoxynucleotides in the presence of a DNA double-strand break

21 January 2018

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Double-stranded break can be repaired by single-stranded oligonucleotides via the ATM/ATR pathway in mammalian cells

21 January 2018

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Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications

21 January 2018

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High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

21 January 2018

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Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes

21 January 2018

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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

21 January 2018

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Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy

21 January 2018

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Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

21 January 2018

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In vivo genome editing restores haemostasis in a mouse model of haemophilia

21 January 2018

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10.1517/14712598.2012.660522

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22321001%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference