(Q37986328)

26 August 2017

Evolutionary functional analysis and molecular regulation of the ZEB transcription factors (English)

1 reference

26 August 2017

5

Geert Berx

1 reference

26 August 2017

Paco Hulpiau

2

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author name string

Alexander Gheldof

series ordinal

1

1 reference

PubMed ID

22349261

26 August 2017

Frans van Roy

series ordinal

3

1 reference

PubMed ID

22349261

26 August 2017

Bram De Craene

series ordinal

4

1 reference

26 August 2017

21 February 2012

1 reference

Cellular and Molecular Life Sciences

26 August 2017

1 reference

26 August 2017

69

1 reference

26 August 2017

15

1 reference

26 August 2017

2527-2541

1 reference

https://scigraph.springernature.com/pub.10.1007/s00018-012-0935-3

26 August 2017

0 references

cites work

The role of the ZEB family of transcription factors in development and disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Identification of a Zinc Finger Protein that Inhibits IL-2 Gene Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

BZP, a novel serum-responsive zinc finger protein that inhibits gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Displacement of an E-box-binding repressor by basic helix-loop-helix proteins: implications for B-cell specificity of the immunoglobulin heavy-chain enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Transcription factors positively and negatively regulating the Na,K-ATPase alpha 1 subunit gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

DNA binding through distinct domains of zinc-finger-homeodomain protein AREB6 has different effects on gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The chordate amphioxus: an emerging model organism for developmental biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Gene duplication, co-option and recruitment during the origin of the vertebrate brain from the invertebrate chordate brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Evolutionary crossroads in developmental biology: the tunicates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Expression of avian C-terminal binding proteins (Ctbp1 and Ctbp2) during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Organization of the mouse Zfhx1b gene encoding the two-handed zinc finger repressor Smad-interacting protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Opposing LSD1 complexes function in developmental gene activation and repression programmes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The evolution of signalling pathways in animal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Classification and nomenclature of all human homeobox genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Hox genes and regional patterning of the vertebrate body plan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

21 January 2018

Homeodomain interactions

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Combination of a zinc finger and homeodomain required for protein-interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Analysis of homeodomain function by structure-based design of a transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Zinc fingers: gilt by association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The discovery of zinc fingers and their applications in gene regulation and genome manipulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Keep your fingers off my DNA: protein-protein interactions mediated by C2H2 zinc finger domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The delta-crystallin enhancer-binding protein delta EF1 is a repressor of E2-box-mediated gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Impairment of T cell development in deltaEF1 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Transcriptional activation of ZEB1 by Slug leads to cooperative regulation of the epithelial-mesenchymal transition-like phenotype in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Functional cooperation between Snail1 and twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

ZEB1 links p63 and p73 in a novel neuronal survival pathway rapidly induced in response to cortical ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Identification of new p63 targets in human keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Involvement of negative cofactor NC2 in active repression by zinc finger-homeodomain transcription factor AREB6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Requirement of a corepressor for Dr1-mediated repression of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

ZEB1 and CtBP form a repressive complex at a distal promoter element of the BCL6 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

ZEB represses transcription through interaction with the corepressor CtBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

CtBP, an unconventional transcriptional corepressor in development and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Antioncogenic effect of adenovirus E1A in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Adenovirus E1A: remodelling the host cell, a life or death experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Evidence for a function of CtBP in epithelial gene regulation and anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

XSip1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Coordinated histone modifications mediated by a CtBP co-repressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Concepts in sumoylation: a decade on

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The polycomb protein Pc2 is a SUMO E3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Cell-specific phosphorylation of Zfhep transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

TGF-beta signaling in cancer--a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

TGF-beta-induced epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

deltaEF1 and SIP1 are differentially expressed and have overlapping activities during Xenopus embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Molecular characterization of TGFbeta-induced epithelial-mesenchymal transition in normal finite lifespan human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

In vivo and in vitro evidence for transforming growth factor-beta1-mediated epithelial to mesenchymal transition in esophageal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia/lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Inducible expression of TGFβ, snail and Zeb1 recapitulates EMT in vitro and in vivo in a NSCLC model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Activation of epidermal growth factor receptor results in snail protein but not mRNA overexpression in endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Downregulation of microRNAs directs the EMT and invasive potential of anaplastic thyroid carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

miR-200a Prevents renal fibrogenesis through repression of TGF-β2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Suppression of TGFβ-induced epithelial-mesenchymal transition like phenotype by a PIAS1 regulated sumoylation pathway in NMuMG epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

ZEB1-responsive genes in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0935-3

DeltaEF1, a zinc finger and homeodomain transcription factor, is required for skeleton patterning in multiple lineages

21 January 2018

1 reference

12 December 2020

Delta-crystallin enhancer binding protein delta EF1 is a zinc finger-homeodomain protein implicated in postgastrulation embryogenesis.

1 reference

12 December 2020

A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis

1 reference

12 December 2020

Origins and plasticity of neural crest cells and their roles in jaw and craniofacial evolution

1 reference

12 December 2020

Identification of DeltaEF1 as a novel target that is negatively regulated by LMO2 in T-cell leukemia

1 reference

12 December 2020

The N-terminus zinc finger domain of Xenopus SIP1 is important for neural induction, but not for suppression of Xbra expression

1 reference

12 December 2020

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes

1 reference

12 December 2020

10.1007/S00018-012-0935-3

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22349261