(Q37995667)

26 August 2017

title

Role of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants (English)

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26 August 2017

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Frederick A Beland

2

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author name string

Igor Koturbash

series ordinal

1

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26 August 2017

Igor P Pogribny

series ordinal

3

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26 August 2017

language of work or name

English

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publication date

21 March 2012

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Expert Opinion on Drug Metabolism & Toxicology

26 August 2017

published in

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26 August 2017

volume

8

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26 August 2017

issue

5

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26 August 2017

page(s)

597-606

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Environmental exposure measurement in cancer epidemiology

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Discovering environmental causes of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Induction of phase I, II and III drug metabolism/transport by xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Genetic basis of toxic reactions to drugs and chemicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Clinically relevant genetic variations in drug metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Epigenetic regulation of genes encoding drug-metabolizing enzymes and transporters; DNA methylation and other mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Xenobiotic-activated receptors: from transcription to drug metabolism to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Role of microRNAs in the regulation of drug metabolism and disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Toxicological implications of modulation of gene expression by microRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA pharmacogenomics: post-transcriptional regulation of drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Mammalian microRNAs predominantly act to decrease target mRNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Regulation of mRNA translation and stability by microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

RNA polymerase III transcribes human microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Functional relevance of miRNA sequences in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

21 January 2018

Genomics of microRNA.

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

The complexities of microRNA regulation: mirandering around the rules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

A microRNA component of the p53 tumour suppressor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Widespread microRNA repression by Myc contributes to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Targeting microRNAs in cancer: rationale, strategies and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Genetic variation in microRNA networks: the implications for cancer research

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Genetic variation in an miRNA-1827 binding site in MYCL1 alters susceptibility to small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Methylation of human microRNA genes in normal and neoplastic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Epigenetic regulation of microRNAs in cancer: an integrated review of literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Most mammalian mRNAs are conserved targets of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

p16(INK4a) translation suppressed by miR-24

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

miR-148 targets human DNMT3b protein coding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA-373 induces expression of genes with complementary promoter sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Metabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

The role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Expression of CYP1A1 and CYP1B1 depends on cell-specific factors in human breast cancer cell lines: role of estrogen receptor status

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Human CYP1B1 is regulated by estradiol via estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

CYP2E1 and risk of chemically mediated cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Human CYP2E1 is regulated by miR-378.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Retinoids activate the RXR/SXR-mediated pathway and induce the endogenous CYP3A4 activity in Huh7 human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Glutathione transferases: a structural perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Nrf2: control of sensitivity to carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Tissue-specific function of farnesoid X receptor in liver and intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA-421 functions as an oncogenic miRNA in biliary tract cancer through down-regulating farnesoid X receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA hsa-miR-613 targets the human LXRα gene and mediates a feedback loop of LXRα autoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA 506 regulates expression of PPAR alpha in hydroxycamptothecin-resistant human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

PPARα is regulated by miR-21 and miR-27b in human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Targeting multidrug resistance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Role of the breast cancer resistance protein (ABCG2) in drug transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Downregulation of miR-122 in the rodent and human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Environmental chemicals and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

RDX induces aberrant expression of microRNAs in mouse brain and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

miR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Epigenetic changes induced by air toxics: formaldehyde exposure alters miRNA expression profiles in human lung cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Circulating microRNAs, potential biomarkers for drug-induced liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Plasma MicroRNAs as sensitive and specific biomarkers of tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Involvement of microRNAs in dioxin-induced liver damage in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Plasma miR-208 as a biomarker of myocardial injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Widespread changes in protein synthesis induced by microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.673587

10.1517/17425255.2012.673587

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference