(Q37996396)

26 August 2017

title

Secreted virulence factors and immune evasion in visceral leishmaniasis (English)

1 reference

evasion of host immune response

26 August 2017

main subject

visceral leishmaniasis

1 reference

based on heuristic

inferred from title

1 reference

6

Leonard J Foster

1 reference

26 August 2017

Ulrike Lambertz

1

1 reference

26 August 2017

Judith Maxwell Silverman

2

1 reference

26 August 2017

Devki Nandan

3

1 reference

26 August 2017

W Robert McMaster

4

1 reference

26 August 2017

Joachim Clos

5

1 reference

26 August 2017

Neil E Reiner

7

1 reference

26 August 2017

publication date

21 March 2012

1 reference

Journal of Leukocyte Biology

26 August 2017

published in

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26 August 2017

volume

91

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26 August 2017

issue

6

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26 August 2017

page(s)

887-899

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Recognition of microorganisms and activation of the immune response

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania lipophosphoglycan activates the transcription factor activating protein 1 in J774A.1 macrophages through the extracellular signal-related kinase (ERK) and p38 mitogen-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania EF-1alpha activates the Src homology 2 domain containing tyrosine phosphatase SHP-1 leading to macrophage deactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Proteomic analysis of the secretome of Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Inhibition of protein kinase C activity by the Leishmania donovani lipophosphoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Novel role for the double-stranded RNA-activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Human cutaneous leishmaniasis: interferon-dependent expression of double-stranded RNA-dependent protein kinase (PKR) via TLR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania-induced increases in activation of macrophage SHP-1 tyrosine phosphatase are associated with impaired IFN-gamma-triggered JAK2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania donovani amastigotes impair gamma interferon-induced STAT1alpha nuclear translocation by blocking the interaction between STAT1alpha and importin-alpha5

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Role of host protein tyrosine phosphatase SHP-1 in Leishmania donovani-induced inhibition of nitric oxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania promastigotes activate PI3K/Akt signalling to confer host cell resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Activation of PI3K/Akt signaling has a dominant negative effect on IL-12 production by macrophages infected with Leishmania amazonensis promastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Effective clearance of intracellularLeishmania majorin vivo requires Pten in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

The p110 delta isoform of phosphatidylinositol 3-kinase controls the quality of secondary anti-Leishmania immunity by regulating expansion and effector function of memory T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Myeloid cell IL-10 production in response to leishmania involves inactivation of glycogen synthase kinase-3β downstream of phosphatidylinositol-3 kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Activation of p38 mitogen-activated protein kinase attenuates Leishmania donovani infection in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Role of host phosphotyrosine phosphatase SHP-1 in the development of murine leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Regulation of the Leishmania-induced innate inflammatory response by the protein tyrosine phosphatase SHP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania major intracellular survival is not altered in SHP-1 deficient mev or CD45-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Regulation of macrophage nitric oxide production by the protein tyrosine phosphatase Src homology 2 domain phosphotyrosine phosphatase 1 (SHP-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

MAPK-directed phosphatases preferentially regulate pro- and anti-inflammatory cytokines in experimental visceral leishmaniasis: involvement of distinct protein kinase C isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Targeting malaria virulence and remodeling proteins to the host erythrocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Identification of leishmania fructose-1,6-bisphosphate aldolase as a novel activator of host macrophage Src homology 2 domain containing protein tyrosine phosphatase SHP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Schistosomal‐Derived Lysophosphatidylcholine Are Involved in Eosinophil Activation and Recruitment through Toll‐Like Receptor–2–Dependent Mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Approaches to the study of the cell secretome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Secretory pathway of trypanosomatid parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Intracellular trafficking in the trypanosomatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Approaches for the identification of potential excreted/secreted proteins of Leishmania major parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

The major surface-metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide-induced apoptotic killing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Acylation-dependent Protein Export in Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Secretome: clues into pathogen infection and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

The Ld Cht1 gene encodes the secretory chitinase of the human pathogen Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Biosynthesis and secretion of acid phosphatase by Leishmania donovani promastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Proteomic characterization of the released/secreted proteins of Leishmania (Viannia) braziliensis promastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania infantum chagasi: a genome-based approach to identification of excreted/secreted proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

An experimental approach for the identification of conserved secreted proteins in trypanosomatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Localization and induction of the A2 virulence factor in Leishmania: evidence that A2 is a stress response protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania donovani engages in regulatory interference by targeting macrophage protein tyrosine phosphatase SHP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Major surface protease of trypanosomatids: one size fits all?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Biosynthesis of the major surface protease GP63 of Leishmania chagasi

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Extracellular release of the glycosylphosphatidylinositol (GPI)-linked Leishmania surface metalloprotease, gp63, is independent of GPI phospholipolysis: implications for parasite virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Processing and trafficking of Leishmania mexicana GP63. Analysis using GP18 mutants deficient in glycosylphosphatidylinositol protein anchoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania and Trypanosoma surface glycoproteins have a common glycophospholipid membrane anchor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Peptide substrate specificity of the membrane-bound metalloprotease of Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Migration through the extracellular matrix by the parasitic protozoan Leishmania is enhanced by surface metalloprotease gp63.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Internal and surface-localized major surface proteases of Leishmania spp. and their differential release from promastigotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Fibronectin binding and proteolytic degradation by Leishmania and effects on macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Epitope cleavage by Leishmania endopeptidase(s) limits the efficiency of the exogenous pathway of major histocompatibility complex class I-associated antigen presentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

A novel form of NF-kappaB is induced by Leishmania infection: involvement in macrophage gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen-activated protein kinase inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania donovani: immunochemical localization and secretory mechanism of soluble acid phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Members of a unique histidine acid phosphatase family are conserved amongst a group of primitive eukaryotic human pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Two tandemly arrayed genes encode the (histidine) secretory acid phosphatases of Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Mycobacterial infection of macrophages results in membrane-permeable phagosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Cysteine peptidases as virulence factors of Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Exosomes: from biogenesis and secretion to biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Ceramide triggers budding of exosome vesicles into multivesicular endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Exosomes: extracellular organelles important in intercellular communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Membrane vesicles as conveyors of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Temperature-induced protein secretion by Leishmania mexicana modulates macrophage signalling and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

A novel role for 100 kD heat shock proteins in the parasite Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania major Hsp100 is required chiefly in the mammalian stage of the parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Vector transmission of leishmania abrogates vaccine-induced protective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

SIR2-deficient Leishmania infantum induces a defined IFN-gamma/IL-10 pattern that correlates with protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Second-generation vaccines against leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmanial antigens in liposomes promote protective immunity and provide immunotherapy against visceral leishmaniasis via polarized Th1 response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Chlamydia muridarum T-cell antigens formulated with the adjuvant DDA/TDB induce immunity against infection that correlates with a high frequency of gamma interferon (IFN-gamma)/tumor necrosis factor alpha and IFN-gamma/interleukin-17 double-positive

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Cationic liposomes as vaccine adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Fragments of antigen-loaded dendritic cells (DC) and DC-derived exosomes induce protective immunity against Leishmania major.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Toxoplasma gondii antigen-pulsed-dendritic cell-derived exosomes induce a protective immune response against T. gondii infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Exosomes and cancer: a newly described pathway of immune suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Determining Adjuvant Activity on T-Cell Function In Vivo: Th Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0611326

21 January 2018

Identifiers

DOI

10.1189/JLB.0611326

1 reference

26 August 2017

1 reference