(Q38008495)

26 August 2017

Translational control in cellular and developmental processes (English)

1 reference

26 August 2017

Paul Lasko

2

0 references

author name string

Jian Kong

series ordinal

1

1 reference

PubMed ID

22568971

26 August 2017

language of work or name

1 reference

1 June 2012

1 reference

26 August 2017

Nature Reviews Genetics

1 reference

26 August 2017

13

1 reference

26 August 2017

6

1 reference

26 August 2017

383-394

1 reference

https://scigraph.springernature.com/pub.10.1038/nrg3184

26 August 2017

0 references

cites work

Understanding neuronal connectivity through the post-transcriptional toolkit

1 reference

Global quantification of mammalian gene expression control

21 January 2018

1 reference

Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function.

21 January 2018

1 reference

Non-coding RNAs in human disease

21 January 2018

1 reference

Toward a structural understanding of IRES RNA function

21 January 2018

1 reference

Cap- and IRES-independent scanning mechanism of translation initiation as an alternative to the concept of cellular IRESs.

21 January 2018

1 reference

The mechanism of eukaryotic translation initiation and principles of its regulation

21 January 2018

1 reference

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

21 January 2018

1 reference

Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins

21 January 2018

1 reference

Upstream and downstream of mTOR

21 January 2018

1 reference

The mechanism of insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR) complex 1 and its contribution to mTOR complex 1 signaling

21 January 2018

1 reference

mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs

21 January 2018

1 reference

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2

21 January 2018

1 reference

FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging

21 January 2018

1 reference

4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila

21 January 2018

1 reference

Dissolution of the maskin-eIF4E complex by cytoplasmic polyadenylation and poly(A)-binding protein controls cyclin B1 mRNA translation and oocyte maturation

21 January 2018

1 reference

Translational control of the embryonic cell cycle.

21 January 2018

1 reference

Differential phosphorylation controls Maskin association with eukaryotic translation initiation factor 4E and localization on the mitotic apparatus

21 January 2018

1 reference

CDK1 and calcineurin regulate Maskin association with eIF4E and translational control of cell cycle progression.

21 January 2018

1 reference

Drosophila cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis

21 January 2018

1 reference

Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression

21 January 2018

1 reference

CUP promotes deadenylation and inhibits decapping of mRNA targets.

21 January 2018

1 reference

Smaug assembles an ATP-dependent stable complex repressing nanos mRNA translation at multiple levels.

21 January 2018

1 reference

Making synaptic plasticity and memory last: mechanisms of translational regulation

21 January 2018

1 reference

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

21 January 2018

1 reference

Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms

21 January 2018

1 reference

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

21 January 2018

1 reference

Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos

21 January 2018

1 reference

Cytoplasmic Prep1 interacts with 4EHP inhibiting Hoxb4 translation

21 January 2018

1 reference

HOXB4-induced expansion of adult hematopoietic stem cells ex vivo.

21 January 2018

1 reference

ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP

21 January 2018

1 reference

Functional analysis of seven genes encoding eight translation initiation factor 4E (eIF4E) isoforms in Drosophila

21 January 2018

1 reference

SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase.

21 January 2018

1 reference

Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression.

21 January 2018

1 reference

Translational control of maternal Cyclin B mRNA by Nanos in the Drosophila germline.

21 January 2018

1 reference

A deadenylation negative feedback mechanism governs meiotic metaphase arrest.

21 January 2018

1 reference

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo

21 January 2018

1 reference

Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA.

21 January 2018

1 reference

Cytoplasmic polyadenylation element (CPE)- and CPE-binding protein (CPEB)-independent mechanisms regulate early class maternal mRNA translational activation in Xenopus oocytes

21 January 2018

1 reference

MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes.

21 January 2018

1 reference

Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA.

21 January 2018

1 reference

Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice

21 January 2018

1 reference

Regulation of tumor suppressor p53 at the RNA level

21 January 2018

1 reference

CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation

21 January 2018

1 reference

Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2.

21 January 2018

1 reference

CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation

21 January 2018

1 reference

Upstream open reading frames: molecular switches in (patho)physiology

21 January 2018

1 reference

A dual inhibitory mechanism restricts msl-2 mRNA translation for dosage compensation in Drosophila

21 January 2018

1 reference

The SXL-UNR corepressor complex uses a PABP-mediated mechanism to inhibit ribosome recruitment to msl-2 mRNA.

21 January 2018

1 reference

Translational control via protein-regulated upstream open reading frames.

21 January 2018

1 reference

DDX6 recruits translational silenced human reticulocyte 15-lipoxygenase mRNA to RNP granules

21 January 2018

1 reference

Interaction with eIF5B is essential for Vasa function during development.

21 January 2018

1 reference

Vasa promotes Drosophila germline stem cell differentiation by activating mei-P26 translation by directly interacting with a (U)-rich motif in its 3' UTR.

21 January 2018

1 reference

Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.

21 January 2018

1 reference

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

21 January 2018

1 reference

Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae.

21 January 2018

1 reference

Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD

21 January 2018

1 reference

Compartment-specific, differential regulation of eukaryotic elongation factor 2 and its kinase within Aplysia sensory neurons.

21 January 2018

1 reference

Hypoxia-inducible factors and the response to hypoxic stress

21 January 2018

1 reference

CPEB2-eEF2 interaction impedes HIF-1α RNA translation

21 January 2018

1 reference

Identification of an mRNP complex regulating tumorigenesis at the translational elongation step

21 January 2018

1 reference

A conserved PUF-Ago-eEF1A complex attenuates translation elongation.

21 January 2018

1 reference

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

21 January 2018

1 reference

5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage

21 January 2018

1 reference

The multiple levels of regulation by p53 ubiquitination

21 January 2018

1 reference

Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26

21 January 2018

1 reference

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

21 January 2018

1 reference

The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.

21 January 2018

1 reference

Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemia

21 January 2018

1 reference

The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia

21 January 2018

1 reference

Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia

21 January 2018

1 reference

Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia

21 January 2018

1 reference

Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients

21 January 2018

1 reference

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

21 January 2018

1 reference

Many ribosomal protein genes are cancer genes in zebrafish

21 January 2018

1 reference

Knockdown of ribosomal protein S7 causes developmental abnormalities via p53 dependent and independent pathways in zebrafish

21 January 2018

1 reference

Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning

21 January 2018

1 reference

rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.

21 January 2018

1 reference

Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita

21 January 2018

1 reference

Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis

21 January 2018

1 reference

Loss of ribosomal RNA modification causes developmental defects in zebrafish

21 January 2018

1 reference

RNA granules: post-transcriptional and epigenetic modulators of gene expression

21 January 2018

1 reference

RNA granules: the good, the bad and the ugly

21 January 2018

1 reference

Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation

21 January 2018

1 reference

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein.

21 January 2018

1 reference

Dynamic organization and plasticity of sponge bodies.

21 January 2018

1 reference

Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis

21 January 2018

1 reference

mRNA localization: gene expression in the spatial dimension

21 January 2018

1 reference

Localization, anchoring and translational control of oskar, gurken, bicoid and nanos mRNA during Drosophila oogenesis

21 January 2018

1 reference

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions

21 January 2018

1 reference

Dendritic protein synthesis, synaptic plasticity, and memory

21 January 2018

1 reference

Mechanisms of dendritic mRNA transport and its role in synaptic tagging.

21 January 2018

1 reference

Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate.

21 January 2018

1 reference

Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor

21 January 2018

1 reference

Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes

21 January 2018

1 reference

Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport

21 January 2018

1 reference

Splicing of oskar RNA in the nucleus is coupled to its cytoplasmic localization

21 January 2018

1 reference

Dimerization of oskar 3' UTRs promotes hitchhiking for RNA localization in the Drosophila oocyte

21 January 2018

1 reference

A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin

21 January 2018

1 reference

Drosophila Mon2 couples Oskar-induced endocytosis with actin remodeling for cortical anchorage of the germ plasm

21 January 2018

1 reference

Stimulation of endocytosis and actin dynamics by Oskar polarizes the Drosophila oocyte.

21 January 2018

1 reference

In vivo imaging of oskar mRNA transport reveals the mechanism of posterior localization

21 January 2018

1 reference

ZBP1 recognition of beta-actin zipcode induces RNA looping

21 January 2018

1 reference

Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud.

21 January 2018

1 reference

Multiple Myo4 motors enhance ASH1 mRNA transport in Saccharomyces cerevisiae

21 January 2018

1 reference

A cytoplasmic complex mediates specific mRNA recognition and localization in yeast

21 January 2018

1 reference

Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling

21 January 2018

1 reference

Comprehensive analysis of diverse ribonucleoprotein complexes.

21 January 2018

1 reference

The maternal-to-zygotic transition: a play in two acts

21 January 2018

1 reference

Posttranscriptional regulation in Drosophila oocytes and early embryos

21 January 2018

1 reference

21 January 2018

A cup full of functions

1 reference

Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles

21 January 2018

1 reference

Cup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development.

21 January 2018

1 reference

Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F

21 January 2018

1 reference

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

21 January 2018

1 reference

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

21 January 2018

1 reference

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.

21 January 2018

1 reference

Regulation of molecular pathways in the Fragile X Syndrome: insights into Autism Spectrum Disorders

21 January 2018

1 reference

Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster

21 January 2018

1 reference

The widespread regulation of microRNA biogenesis, function and decay

21 January 2018

1 reference

Impaired myelopoiesis in mice lacking the repressors of translation initiation, 4E-BP1 and 4E-BP2

31 March 2020

1 reference

Mechanism of elongation factor 2 (EF-2) inactivation upon phosphorylation. Phosphorylated EF-2 is unable to catalyze translocation

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG3184

1 reference

PubMed ID

22568971

Dimensions Publication ID

26 August 2017

0 references

1 reference

PubMed ID

22568971