(Q37715822)

22 August 2017

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title

Regulation of tumor suppressor p53 at the RNA level (English)

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22 August 2017

Anna Vilborg

1

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Margareta Wilhelm

object named as

Margareta T Wilhelm

series ordinal

2

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Klas Wiman

object named as

Klas G Wiman

series ordinal

3

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publication date

21 March 2010

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Journal of Molecular Medicine

22 August 2017

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22 August 2017

88

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22 August 2017

7

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22 August 2017

645-652

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https://scigraph.springernature.com/pub.10.1007/s00109-010-0609-2

22 August 2017

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cites work

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12 December 2020

Negative feedback regulation of wild-type p53 biosynthesis.

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12 December 2020

Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26

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12 December 2020

Identification of alternate polyadenylation sites and analysis of their tissue distribution using EST data.

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12 December 2020

Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

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12 December 2020

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

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12 December 2020

Wig-1, a new p53-induced gene encoding a zinc finger protein

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Post-transcriptional regulation in cancer

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Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-alpha mRNA.

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mRNA stability control: a clandestine force in normal and malignant hematopoiesis

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Wrap53, a natural p53 antisense transcript required for p53 induction upon DNA damage.

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Stem cells: The promises and perils of p53.

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12 December 2020

Increased expression of cytoplasmic HuR in familial adenomatous polyposis.

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12 December 2020

Modulation of microRNA processing by p53

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12 December 2020

Small silencing RNAs: an expanding universe

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12 December 2020

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

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12 December 2020

MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis

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12 December 2020

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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12 December 2020

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12 December 2020

Restoration of p53 function leads to tumour regression in vivo

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12 December 2020

The p53-induced mouse zinc finger protein wig-1 binds double-stranded RNA with high affinity

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12 December 2020

30 years and a long way into p53 research

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12 December 2020

RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain

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12 December 2020

RNA helicase A mediates association of CBP with RNA polymerase II

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12 December 2020

Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

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12 December 2020

Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells

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12 December 2020

Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets

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12 December 2020

Strategies for therapeutic targeting of the p53 pathway in cancer.

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12 December 2020

Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR.

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12 December 2020

Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression

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12 December 2020

IRES-dependent regulation of FGF-2 mRNA translation in pathophysiological conditions in the mouse

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12 December 2020

Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis

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12 December 2020

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

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12 December 2020

Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for p53 haplo-insufficiency

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12 December 2020

Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements

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12 December 2020

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

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12 December 2020

Blinded by the Light: The Growing Complexity of p53

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12 December 2020

MicroRNA expression profiles classify human cancers

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12 December 2020

The rapid destabilization of p53 mRNA in immortal chicken embryo fibroblast cells

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12 December 2020

The p53-induced Wig-1 protein binds double-stranded RNAs with structural characteristics of siRNAs and miRNAs.

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12 December 2020

1p36: every subband a suppressor?

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12 December 2020

Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.

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12 December 2020

The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element

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12 December 2020

p53 directs conformational change and translation initiation blockade of human fibroblast growth factor 2 mRNA.

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12 December 2020

Radioprotective effect of antioxidative flavonoids in gamma-ray irradiated mice

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12 December 2020

AU-rich elements and associated factors: are there unifying principles?

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12 December 2020

Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage

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12 December 2020

Live or let die: the cell's response to p53

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12 December 2020

P53 mRNA controls p53 activity by managing Mdm2 functions

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12 December 2020

Polyamine Depletion Increases Cytoplasmic Levels of RNA-binding Protein HuR Leading to Stabilization of Nucleophosmin and p53 mRNAs

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12 December 2020

Shaping genetic alterations in human cancer: the p53 mutation paradigm

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12 December 2020

The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis

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12 December 2020

When mutants gain new powers: news from the mutant p53 field.

1 reference

12 December 2020

MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells

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12 December 2020

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

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12 December 2020

p53 has a direct apoptogenic role at the mitochondria

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12 December 2020

A translation repressor element resides in the 3' untranslated region of human p53 mRNA

1 reference

12 December 2020

Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma

1 reference

12 December 2020

A microRNA component of the p53 tumour suppressor network

1 reference

12 December 2020

RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation

1 reference

12 December 2020

An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells

1 reference

12 December 2020

Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells

1 reference

12 December 2020

p53 binds selectively to the 5' untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta- and p53-mediated translational inhibition of cdk4.

1 reference

12 December 2020

RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator

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12 December 2020

Compromised HOXA5 function can limit p53 expression in human breast tumours

1 reference

12 December 2020

The identification of an internal ribosomal entry site in the 5'-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage

1 reference

12 December 2020

Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells

1 reference

12 December 2020

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.

1 reference

12 December 2020

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

1 reference

12 December 2020

The p53-induced Wig-1 zinc finger protein is highly conserved from fish to man.

1 reference

12 December 2020

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth

1 reference

12 December 2020

Participation of p53 protein in the cellular response to DNA damage

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12 December 2020

A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis

1 reference

12 December 2020

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

1 reference

12 December 2020

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

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12 December 2020

Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

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12 December 2020

Suppression of p53-activated gene, PAG608, attenuates methamphetamine-induced neurotoxicity.

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12 December 2020

Characterization of microRNA expression levels and their biological correlates in human cancer cell lines

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12 December 2020

Two internal ribosome entry sites mediate the translation of p53 isoforms.

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12 December 2020

p53 and little brother p53/47: linking IRES activities with protein functions

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12 December 2020

Enhancement of p53 expression in keratinocytes by the bioflavonoid apigenin is associated with RNA-binding protein HuR.

1 reference

12 December 2020

p53-dependent ICAM-1 overexpression in senescent human cells identified in atherosclerotic lesions

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12 December 2020

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12 December 2020

Heterogeneous nuclear ribonucleoprotein-A2/B1 modulate collagen prolyl 4-hydroxylase, alpha (I) mRNA stability

1 reference

12 December 2020

RNA helicase A is necessary for translation of selected messenger RNAs

1 reference

12 December 2020

Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2.

1 reference

12 December 2020

Revisiting the principles of microRNA target recognition and mode of action

1 reference

12 December 2020

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

1 reference

12 December 2020

HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs

1 reference

12 December 2020

MicroRNA-125b is a novel negative regulator of p53.

1 reference

12 December 2020

1 reference

12 December 2020

Surfing the p53 network

1 reference

12 December 2020

Biased alternative polyadenylation in human tissues

1 reference

12 December 2020

MicroRNA 125a and its regulation of the p53 tumor suppressor gene

1 reference

12 December 2020

Impaired microRNA processing enhances cellular transformation and tumorigenesis

1 reference

12 December 2020

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

1 reference

12 December 2020

Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein.

1 reference

12 December 2020

10.1007/S00109-010-0609-2

Identifiers

DOI

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22 August 2017

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PubMed ID

20306257