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Drugging Wnt signalling in cancer
scientific article published on 22 May 2012
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
title
Drugging Wnt signalling in cancer
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
author name string
Paul Polakis
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
language of work or name
English
0 references
publication date
22 May 2012
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
volume
31
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
page(s)
2737-2746
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
issue
12
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
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Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin
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Identification and characterization of the familial adenomatous polyposis coli gene
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6 September 2017
FZD7 has a critical role in cell proliferation in triple negative breast cancer
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PubMed Central
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6 September 2017
Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth.
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14 September 2017
β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells
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14 September 2017
Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.
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14 September 2017
Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo
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14 September 2017
beta-catenin small interfering RNA successfully suppressed progression of multiple myeloma in a mouse model
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14 September 2017
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling
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14 September 2017
The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
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14 September 2017
An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth.
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14 September 2017
Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954.
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14 September 2017
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
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14 September 2017
Regulation of Lef-mediated transcription and p53-dependent pathway by associating beta-catenin with CBP/p300.
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28 September 2017
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
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23 June 2018
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
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23 June 2018
Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells.
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31 August 2018
beta-Catenin and p53 analyses of a breast carcinoma tissue microarray.
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31 August 2018
Suppression of beta-catenin inhibits the neoplastic growth of APC-mutant colon cancer cells.
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31 August 2018
Colorectal Tumors Are Effectively Eradicated by Combined Inhibition of -Catenin, KRAS, and the Oncogenic Transcription Factor ITF2
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21 January 2018
Proof-of-principle: oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
AXIN2-associated autosomal dominant ectodermal dysplasia and neoplastic syndrome
1 reference
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Beta-catenin antisense treatment decreases beta-catenin expression and tumor growth rate in colon carcinoma xenografts
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/22617421
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/EMBOJ.2012.126
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
PMCID
3380214
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
PubMed ID
22617421
1 reference
stated in
Europe PubMed Central
PMCID
3380214
retrieved
27 August 2017
ResearchGate publication ID
225056155
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