(Q38014989)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22651914%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22651914%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22651914%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Andrew P Hinck

series ordinal

1

1 reference

27 August 2017

language of work or name

English

0 references

publication date

28 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22651914%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22651914%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

586

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22651914%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22651914%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

1860-1870

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22651914%20AND%20SRC:MED&resulttype=core&format=json

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

2 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Transforming growth factor-beta 3 is required for secondary palate fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Regulation of immune responses by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Transforming growth factor beta s and wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Tumor suppressor activity of the TGF-beta pathway in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The two faces of transforming growth factor beta in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The role of BMPs and GDFs in development of region-specific skeletal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Inhibin, activin and the female reproductive axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Cytokines and invertebrates: TGF-beta and PDGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The Drosophila Activin-like ligand Dawdle signals preferentially through one isoform of the Type-I receptor Baboon

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

TGF beta signals through a heteromeric protein kinase receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Mechanism of activation of the TGF-beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Transcriptional control by the TGF-beta/Smad signaling system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Metastasis is driven by sequential elevation of H-ras and Smad2 levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Determinants of specificity in TGF-beta signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Cloning and characterization of a human type II receptor for bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Crystal structure of the BMP-2-BRIA ectodomain complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Structure of the ternary signaling complex of a TGF-beta superfamily member

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Ternary Complex of Transforming Growth Factor- 1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Assembly of TbetaRI:TbetaRII:TGFbeta ternary complex in vitro with receptor extracellular domains is cooperative and isoform-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Molecular recognition of BMP-2 and BMP receptor IA

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The T?R-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Solution structure and backbone dynamics of the TGFbeta type II receptor extracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

A single residue of GDF-5 defines binding specificity to BMP receptor IB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Intricacies of BMP receptor assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

A flexible activin explains the membrane-dependent cooperative assembly of TGF-beta family receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Identification of a functional binding site for activin on the type I receptor ALK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The interaction of BMP-7 and ActRII implicates a new mode of receptor assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Crystal structure of BMP-9 and functional interactions with pro-region and receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Crystal structure of recombinant human growth and differentiation factor 5: evidence for interaction of the type I and type II receptor-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

Structural basis for the inhibition of activin signalling by follistatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

COBALT: constraint-based alignment tool for multiple protein sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028

The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.05.028