(Q38015229)

27 August 2017

Strategies for the discovery and development of therapies for metastatic breast cancer (English)

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27 August 2017

metastatic breast cancer

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2

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27 August 2017

Bedrich L Eckhardt

1

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27 August 2017

Belinda S Parker

series ordinal

3

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27 August 2017

Robin L Anderson

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4

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27 August 2017

1 June 2012

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Nature Reviews Drug Discovery

27 August 2017

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27 August 2017

11

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27 August 2017

6

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27 August 2017

479-497

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https://scigraph.springernature.com/pub.10.1038/nrd2372

27 August 2017

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Genetic determinants of cancer metastasis

31 March 2020

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A multigenic program mediating breast cancer metastasis to bone

31 March 2020

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Learning therapeutic lessons from metastasis suppressor proteins

31 March 2020

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Three-dimensional context regulation of metastasis

31 March 2020

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The role of the organ microenvironment in the biology and therapy of cancer metastasis

31 March 2020

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Invasiveness of transformed human breast epithelial cell lines is related to cathepsin B and inhibited by cysteine proteinase inhibitors

31 March 2020

1 reference

The microenvironment of the tumour-host interface

31 March 2020

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Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

31 March 2020

1 reference

ECM and cell surface proteolysis: regulating cellular ecology

31 March 2020

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Integrin activation controls metastasis in human breast cancer

31 March 2020

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Involvement of chemokine receptors in breast cancer metastasis

31 March 2020

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In vivo magnetic resonance imaging of single cells in mouse brain with optical validation

31 March 2020

1 reference

Cancer spread and micrometastasis development: quantitative approaches for in vivo models.

31 March 2020

1 reference

Circulating tumor cells in patients with breast cancer dormancy

31 March 2020

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Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.

31 March 2020

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Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype

31 March 2020

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Adaptive immunity maintains occult cancer in an equilibrium state

31 March 2020

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Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma.

31 March 2020

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Role of angiogenesis in tumor growth and metastasis

31 March 2020

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Molecular mechanisms and clinical applications of angiogenesis

31 March 2020

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Angiogenesis: an organizing principle for drug discovery?

31 March 2020

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Clinical translation of angiogenesis inhibitors

31 March 2020

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Bevacizumab added to neoadjuvant chemotherapy for breast cancer

31 March 2020

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Drug insight: VEGF as a therapeutic target for breast cancer

31 March 2020

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Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis

31 March 2020

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Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization

31 March 2020

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Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors

31 March 2020

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Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells.

31 March 2020

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LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan

31 March 2020

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Podoplanin: a novel diagnostic immunohistochemical marker

31 March 2020

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Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation.

31 March 2020

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Insights into the mechanisms of lymph node metastasis

31 March 2020

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Role of lymphangiogenesis in cancer

31 March 2020

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Targeting lymphangiogenesis to prevent tumour metastasis

31 March 2020

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Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

31 March 2020

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

31 March 2020

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Stromal fibroblasts in cancer initiation and progression

31 March 2020

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TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

31 March 2020

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Identification of fibroblast heterogeneity in the tumor microenvironment

31 March 2020

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Suppression of tumor development and metastasis formation in mice lacking the S100A4(mts1) gene

31 March 2020

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Distinct epigenetic changes in the stromal cells of breast cancers

31 March 2020

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Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

31 March 2020

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Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts.

31 March 2020

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Putting tumours in context

31 March 2020

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Myoepithelial cells: good fences make good neighbors

31 March 2020

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31 March 2020

Inflammation and cancer

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Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization

31 March 2020

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Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

31 March 2020

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A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.

31 March 2020

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Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells

31 March 2020

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Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

31 March 2020

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Murine mammary carcinoma 4T1 induces a leukemoid reaction with splenomegaly: association with tumor-derived growth factors.

31 March 2020

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Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

31 March 2020

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Myeloid-derived suppressor cells are implicated in regulating permissiveness for tumor metastasis during mouse gestation.

31 March 2020

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

31 March 2020

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Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.

31 March 2020

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The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages

31 March 2020

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Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes

31 March 2020

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Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

31 March 2020

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c-FMS inhibitors: a patent review

31 March 2020

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Inflammatory cells during wound repair: the good, the bad and the ugly

31 March 2020

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Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

31 March 2020

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The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase

31 March 2020

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

31 March 2020

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Breast cancer lung metastasis requires expression of chemokine receptor CCR4 and regulatory T cells.

31 March 2020

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Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

31 March 2020

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Synthetic lethality--a new direction in cancer-drug development

31 March 2020

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Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study

31 March 2020

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Novel agents on the horizon for cancer therapy

31 March 2020

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Translating cancer research into targeted therapeutics

31 March 2020

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Breast cancer in 2010: Novel targets and therapies for a personalized approach

31 March 2020

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Molecular therapy of breast cancer: progress and future directions

31 March 2020

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Combining emerging agents in advanced breast cancer

31 March 2020

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Microarrays bring new insights into understanding of breast cancer metastasis to bone

31 March 2020

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Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer

31 March 2020

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Frequent genetic differences between matched primary and metastatic breast cancer provide an approach to identification of biomarkers for disease progression

31 March 2020

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Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction

31 March 2020

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Gene expression predictors in breast cancer: current status, limitations and perspectives

31 March 2020

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Trial assessing individualized options for treatment for breast cancer: the TAILORx trial

31 March 2020

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Clinical application of the 70-gene profile: the MINDACT trial

31 March 2020

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The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer.

31 March 2020

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Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial

31 March 2020

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HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: a pooled analysis of randomized trials

31 March 2020

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HER2 and responsiveness of breast cancer to adjuvant chemotherapy.

31 March 2020

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Circulating tumor cells as prognostic and predictive markers in metastatic breast cancer patients receiving first-line systemic treatment

31 March 2020

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Circulating tumor cells at each follow-up time point during therapy of metastatic breast cancer patients predict progression-free and overall survival

31 March 2020

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Circulating tumor cells and [18F]fluorodeoxyglucose positron emission tomography/computed tomography for outcome prediction in metastatic breast cancer.

31 March 2020

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Circulating tumor cells in metastatic breast cancer: from prognostic stratification to modification of the staging system?

31 March 2020

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Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer

31 March 2020

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Circulating tumor cells, disease progression, and survival in metastatic breast cancer

31 March 2020

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Monitoring the response of circulating epithelial tumor cells to adjuvant chemotherapy in breast cancer allows detection of patients at risk of early relapse

31 March 2020

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Quantification of the response of circulating epithelial cells to neodadjuvant treatment for breast cancer: a new tool for therapy monitoring

31 March 2020

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Circulating tumor cell detection predicts early metastatic relapse after neoadjuvant chemotherapy in large operable and locally advanced breast cancer in a phase II randomized trial.

31 March 2020

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Comparison of bone marrow, disseminated tumour cells and blood-circulating tumour cells in breast cancer patients after primary treatment

31 March 2020

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HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial.

31 March 2020

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HER2-positive circulating tumor cells indicate poor clinical outcome in stage I to III breast cancer patients

31 March 2020

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Molecular profiling and predictive value of circulating tumor cells in patients with metastatic breast cancer: an option for monitoring response to breast cancer related therapies

31 March 2020

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HER-2 gene amplification can be acquired as breast cancer progresses

31 March 2020

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Chemokine receptors in advanced breast cancer: differential expression in metastatic disease sites with diagnostic and therapeutic implications

31 March 2020

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Comparison of HER-2 overexpression in primary breast cancer and metastatic sites and its effect on biological targeting therapy of metastatic disease

31 March 2020

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Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients

31 March 2020

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Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells

31 March 2020

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Insights into minimal residual disease in cancer patients: implications for anti-cancer therapies

31 March 2020

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Micrometastatic spread in breast cancer: detection, molecular characterization and clinical relevance

31 March 2020

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Comparison of estrogen and progesterone receptor status of circulating tumor cells and the primary tumor in metastatic breast cancer patients

31 March 2020

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Isolation of a tumor factor responsible for angiogenesis

31 March 2020

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Modes of resistance to anti-angiogenic therapy

31 March 2020

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Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

31 March 2020

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Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

31 March 2020

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Anti-VEGF therapy as adjuvant therapy: clouds on the horizon?

31 March 2020

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Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited

31 March 2020

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31 March 2020

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Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.

31 March 2020

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Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells

31 March 2020

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Playing only one instrument may be not enough: limitations and future of the antiangiogenic treatment of cancer.

31 March 2020

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Metastasis: from dissemination to organ-specific colonization

31 March 2020

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Parathyroid hormone-related protein localization in breast cancers predict improved prognosis.

31 March 2020

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Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ.

31 March 2020

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Review: Biological relevance of disseminated tumor cells in cancer patients

31 March 2020

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Detection, clinical relevance and specific biological properties of disseminating tumour cells

31 March 2020

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Micrometastatic disease in breast cancer: clinical implications

31 March 2020

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Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients

31 March 2020

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Comparison of in vitro and in vivo approaches to studying brain colonization by breast cancer cells.

31 March 2020

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Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases.

31 March 2020

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An experimental model for the treatment of pulmonary metastases

31 March 2020

1 reference

The mighty mouse: genetically engineered mouse models in cancer drug development

31 March 2020

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Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

31 March 2020

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The mutationally activated Met receptor mediates motility and metastasis

31 March 2020

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Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

31 March 2020

1 reference

PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors

31 March 2020

1 reference

Hunk is required for HER2/neu-induced mammary tumorigenesis

31 March 2020

1 reference

Methodological approaches in application of synthetic lethality screening towards anticancer therapy

31 March 2020

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Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models.

31 March 2020

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The clinical course of bone metastases from breast cancer

31 March 2020

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Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer

31 March 2020

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A novel orthotopic model of breast cancer metastasis to bone.

31 March 2020

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Osteoactivin promotes breast cancer metastasis to bone

31 March 2020

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Utilization of guanine by the C57 black mouse bearing adenocarcinoma Eo771.

31 March 2020

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An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells

31 March 2020

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Selection of more aggressive variants of the gI101A human breast cancer cell line: a model for analyzing the metastatic phenotype of breast cancer

31 March 2020

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IL-12 gene-modified bone marrow cell therapy suppresses the development of experimental metastatic prostate cancer

31 March 2020

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A mouse model of human breast cancer metastasis to human bone

31 March 2020

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Genes that mediate breast cancer metastasis to lung

31 March 2020

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A human bone NOD/SCID mouse model to distinguish metastatic potential in primary breast cancers.

31 March 2020

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Efficient engraftment of human primary breast cancer transplants in nonconditioned NOD/Scid mice

31 March 2020

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Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

31 March 2020

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The multiple uses of fluorescent proteins to visualize cancer in vivo

31 March 2020

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Bright and stable near-infrared fluorescent protein for in vivo imaging

31 March 2020

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Applications of positron emission tomography in the development of molecular targeted cancer therapeutics

31 March 2020

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Imaging of integrin alphavbeta3 expression

31 March 2020

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Brain metastases of breast cancer.

31 March 2020

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Imaging and quantifying the dynamics of tumor-associated proteolysis

31 March 2020

1 reference

Cathepsin B inhibition limits bone metastasis in breast cancer

31 March 2020

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Quantitative monitoring of gene expression patterns with a complementary DNA microarray

31 March 2020

1 reference

Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis

31 March 2020

1 reference

Gene expression profiling predicts clinical outcome of breast cancer

31 March 2020

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microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer

31 March 2020

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Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

31 March 2020

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Identification of high risk breast-cancer patients by gene expression profiling

31 March 2020

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Gene-Expression Profiles in Hereditary Breast Cancer

31 March 2020

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Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases

31 March 2020

1 reference

Metastasis Suppressor Genes: Basic Biology and Potential Clinical Use

31 March 2020

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Metastamir: the field of metastasis-regulatory microRNA is spreading

31 March 2020

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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

31 March 2020

1 reference

Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number

31 March 2020

1 reference

MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer

31 March 2020

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Breast cancer methylomes establish an epigenomic foundation for metastasis

31 March 2020

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MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

31 March 2020

1 reference

Metadherin, a cell surface protein in breast tumors that mediates lung metastasis

31 March 2020

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Metastasis suppressors and the tumor microenvironment

31 March 2020

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Metastasis suppression: the evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site

31 March 2020

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The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

31 March 2020

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Autocrine PDGFR signaling promotes mammary cancer metastasis

31 March 2020

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ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells

31 March 2020

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Breast cancer progression: controversies and consensus in the molecular mechanisms of metastasis and EMT

31 March 2020

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The basics of epithelial-mesenchymal transition

31 March 2020

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Molecular requirements for epithelial-mesenchymal transition during tumor progression

31 March 2020

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Epithelial-mesenchymal transitions in tumour progression

31 March 2020

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Epithelial-mesenchymal transitions in development and pathologies

31 March 2020

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Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

31 March 2020

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The epithelial-mesenchymal transition: new insights in signaling, development, and disease

31 March 2020

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Genes that mediate breast cancer metastasis to the brain

31 March 2020

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A molecular signature of metastasis in primary solid tumors

31 March 2020

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Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures

31 March 2020

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Microproteomic analysis of 10,000 laser captured microdissected breast tumor cells using short-range sodium dodecyl sulfate-polyacrylamide gel electrophoresis and porous layer open tubular liquid chromatography tandem mass spectrometry.

31 March 2020

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Organ targeting in vivo using phage display peptide libraries

31 March 2020

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Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries

31 March 2020

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

31 March 2020

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KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer

31 March 2020

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In vivo selection for metastasis promoting genes in the mouse

31 March 2020

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Metastasizing mammary carcinomas in H19 enhancers-Igf2 transgenic mice

31 March 2020

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Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia

31 March 2020

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

31 March 2020

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Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

31 March 2020

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Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice

31 March 2020

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c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

31 March 2020

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Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

31 March 2020

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Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation

31 March 2020

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Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant

31 March 2020

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Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways.

31 March 2020

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Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone.

31 March 2020

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Suppression of human melanoma metastasis by the metastasis suppressor gene, BRMS1.

31 March 2020

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Analysis of mechanisms underlying BRMS1 suppression of metastasis

31 March 2020

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CD44 attenuates metastatic invasion during breast cancer progression

31 March 2020

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KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

31 March 2020

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Reduced invasive and metastatic potentials of KAI1-transfected melanoma cells.

31 March 2020

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KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha

31 March 2020

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KiSS-1, a novel human malignant melanoma metastasis-suppressor gene

31 March 2020

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Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells.

31 March 2020

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Effects of raf kinase inhibitor protein expression on metastasis and progression of human breast cancer

31 March 2020

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Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis

31 March 2020

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Primary tumour expression of the cysteine cathepsin inhibitor Stefin A inhibits distant metastasis in breast cancer.

31 March 2020

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Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice

31 March 2020

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Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancer

31 March 2020

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Connective tissue growth factor inhibits metastasis and acts as an independent prognostic marker in colorectal cancer.

31 March 2020

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Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer

31 March 2020

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Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis

31 March 2020

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The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells

31 March 2020

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The desmoplastic response to infiltrating breast carcinoma: gene expression at the site of primary invasion and implications for comparisons between tumor types

31 March 2020

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12 December 2020

Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

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12 December 2020

Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.

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12 December 2020

Has desmoplastic response extent protective action against tumor aggressiveness in gastric carcinoma?

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12 December 2020

Reduced metastatic potential and c-myc overexpression of colon adenocarcinoma cells (Colon 26 line) transfected with nm23-R2/rat nucleoside diphosphate kinase alpha isoform

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12 December 2020

Overexpression of nm23-H2/NDP kinase B in a human oral squamous cell carcinoma cell line results in reduced metastasis, differentiated phenotype in the metastatic site, and growth factor-independent proliferative activity in culture

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12 December 2020

Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13.

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12 December 2020

Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns

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12 December 2020

Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis

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12 December 2020

Immobilized platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions.

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12 December 2020

Distant metastasis from subcutaneously grown E0771 medullary breast adenocarcinoma.

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12 December 2020

Bioluminescent imaging: a critical tool in pre-clinical oncology research.

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12 December 2020

Prognostic value of desmoplastic reaction and lymphocytic infiltration in the management of breast cancer

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12 December 2020

Heterogeneity of tumor cells from a single mouse mammary tumor

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12 December 2020

Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1

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12 December 2020

A murine model of experimental metastasis to bone and bone marrow.

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12 December 2020

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

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12 December 2020

Changing levels of circulating tumor cells in monitoring chemotherapy response in patients with metastatic breast cancer

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12 December 2020

Histopathology of salivary and mammary gland tumors in transgenic mice expressing a human Ha-ras oncogene

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12 December 2020

Overexpression of KAI1 suppresses in vitro invasiveness and in vivo metastasis in breast cancer cells

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12 December 2020

The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis

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12 December 2020

Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis

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12 December 2020

Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity

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12 December 2020

A soluble transforming growth factor beta type III receptor suppresses tumorigenicity and metastasis of human breast cancer MDA-MB-231 cells

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12 December 2020

Keratinocyte growth factor induces mammary and prostatic hyperplasia and mammary adenocarcinoma in transgenic mice.

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12 December 2020

Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424).

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12 December 2020

Identifiers

DOI

10.1038/NRD2372

1 reference

Dimensions Publication ID

27 August 2017

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