(Q38017702)

22686334

27 August 2017

title

Tight junction in blood-brain barrier: an overview of structure, regulation, and regulator substances (English)

1 reference

27 August 2017

1 reference

Wei-Ye Liu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

Zhi-Bin Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

Li-Chao Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

Xin Wei

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

Ling Li

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

publication date

12 June 2012

1 reference

22686334

CNS Neuroscience & Therapeutics

27 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

page(s)

609-615

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches

14 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Connecting vascular and nervous system development: angiogenesis and the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The blood-brain barrier/neurovascular unit in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Blood-brain barrier delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Mechanisms of disease: the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Modelling of the blood-brain barrier in drug discovery and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Challenges for blood-brain barrier (BBB) screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The blood-brain barrier--lessons from moody flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Tight junction pore and leak pathways: a dynamic duo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Occludin: structure, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

21 January 2018

Tight junction proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Tight junctions of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Complex phenotype of mice lacking occludin, a component of tight junction strands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The blood-brain barrier in health and chronic neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Blood-brain barrier tight junction permeability and ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Molecular anatomy of the brain endothelial barrier: an overview of the distributional features

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Tight junction proteins as channel formers and barrier builders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Adrenomedullin improves the blood-brain barrier function through the expression of claudin-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The blood-brain barrier: an overview: structure, regulation, and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The role of junctional adhesion molecules in vascular inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

JAM family and related proteins in leukocyte migration (Vestweber series).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The JAM family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

ZOning out tight junctions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The dual role of zonula occludens (ZO) proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Early embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Expression and distribution of ZO‐3, a tight junction MAGUK protein, in mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Cingulin interacts with F-actin in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Molecular complexity of vertebrate tight junctions (Review).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Localization of 7H6 tight junction-associated antigen along the cell border of vascular endothelial cells correlates with paracellular barrier function against ions, large molecules, and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The role of tau in Alzheimer's disease and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

TGF-β1 pathway as a new target for neuroprotection in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Blood-brain barrier pathology in Alzheimer's and Parkinson's disease: implications for drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Blood-brain barrier permeability in Alzheimer's disease: a case-control MRI study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The integrity of the blood-brain barrier in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

From hypertension to stroke: mechanisms and potential prevention strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Imaging the future of stroke: I. Ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Protein kinase C activation modulates reversible increase in cortical blood-brain barrier permeability and tight junction protein expression during hypoxia and posthypoxic reoxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Effects of acute hypoxia and hyperthermia on the permeability of the blood-brain barrier in adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

MMP-mediated disruption of claudin-5 in the blood-brain barrier of rat brain after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Disruption of the blood-brain barrier in collagen-induced arthritic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Mortality and cause of death in Japanese patients with rheumatoid arthritis based on a large observational cohort, IORRA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The combination of interferon-beta and HMG-CoA reductase inhibition in multiple sclerosis: enthusiasm lost too soon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Central nervous system penetration for small molecule therapeutic agents does not increase in multiple sclerosis- and Alzheimer's disease-related animal models despite reported blood-brain barrier disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Effect of diabetes on the blood brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Neurodegenerative disorders associated with diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Diabetes, cognitive function, and the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Streptozotocin-induced diabetes progressively increases blood-brain barrier permeability in specific brain regions in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Increased blood-brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Diabetes aggravates nanoparticles induced breakdown of the blood-brain barrier permeability, brain edema formation, alterations in cerebral blood flow and neuronal injury. An experimental study using physiological and morphological investigations in

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The effects of a high-energy diet on hippocampal function and blood-brain barrier integrity in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Mechanisms of the blood-brain barrier disruption in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

HIV-1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

HIV-1-induced alterations of claudin-5 expression at the blood-brain barrier level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

PPARalpha and PPARgamma attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Signaling mechanisms of HIV-1 Tat-induced alterations of claudin-5 expression in brain endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Limited role of COX-2 in HIV Tat-induced alterations of tight junction protein expression and disruption of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Rapid morphological brain abnormalities during acute methamphetamine intoxication in the rat: an experimental study using light and electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Methamphetamine transiently increases the blood-brain barrier permeability in the hippocampus: role of tight junction proteins and matrix metalloproteinase-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Cocaine-mediated induction of platelet-derived growth factor: implication for increased vascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Methamphetamine alters blood brain barrier permeability via the modulation of tight junction expression: Implication for HIV-1 neuropathogenesis in the context of drug abuse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Tight junction regulation by morphine and HIV-1 tat modulates blood-brain barrier permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Cocaine-mediated alteration in tight junction protein expression and modulation of CCL2/CCR2 axis across the blood-brain barrier: implications for HIV-dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Regulation of bovine brain microvascular endothelial tight junction assembly and barrier function by laminar shear stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Paracellular tightness and claudin-5 expression is increased in the BCEC/astrocyte blood-brain barrier model by increasing media buffer capacity during growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Manufactured aluminum oxide nanoparticles decrease expression of tight junction proteins in brain vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Brief heat shock affects the permeability and thermotolerance of an in vitro blood-brain barrier model of porcine brain microvascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Increasing of blood-tumor barrier permeability through paracellular pathway by low-frequency ultrasound irradiation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

EMP-induced alterations of tight junction protein expression and disruption of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

17beta-estradiol differentially regulates blood-brain barrier permeability in young and aging female rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Reproductive age-related changes in the blood brain barrier: expression of IgG and tight junction proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Age and 17β-estradiol effects on blood-brain barrier tight junction and estrogen receptor proteins in ovariectomized rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Occludin as direct target for glucocorticoid-induced improvement of blood-brain barrier properties in a murine in vitro system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Maternal glucocorticoid exposure alters tight junction protein expression in the brain of fetal sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

The impact of DeltaG on the oral bioavailability of low bioavailable therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Tight junction modulation and its relationship to drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Enhancement of brain distribution of anticancer agents using DeltaG, the 12 kDa active fragment of ZOT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Potential use of tight junction modulators to reversibly open membranous barriers and improve drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2012.00340.X

Affinity purification and partial characterization of the zonulin/zonula occludens toxin (Zot) receptor from human brain

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22686334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Altered expression of claudin family proteins in Alzheimer's disease and vascular dementia brains

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22686334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Brain injury associated with widely abused amphetamines: neuroinflammation, neurogenesis and blood-brain barrier.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22686334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1755-5949.2012.00340.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json

14 May 2020

22686334

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493516&resulttype=core&format=json